Naphthalenes

Medchemexpress LLC BI-3231 | 2894848-07-6 | 99.8% | 380.37 | 500 MG

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BI-3231 is a chemical probe that functions as a potent and selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13). It exhibits IC50 values of 1 nM for human HSD17B13 and 13 nM for mouse HSD17B13. This compound holds potential for research into nonalcoholic steatohepatitis (NASH) and various other liver diseases. The BI-3231 probe was developed by Boehringer Ingelheim and is available for free through their open innovation portal, opnMe.com, alongside its negative control.

• Potent and selective HSD17B13 inhibitor.
• IC50 values: 1 nM (hHSD17B13) and 13 nM (mHSD17B13).
• Potential for research in nonalcoholic steatohepatitis (NASH) and liver diseases.
• High metabolic stability in liver microsomes.
• Moderate metabolic stability in hepatocytes.
• Rapidly cleared from plasma, with considerable hepatic exposure maintained over 48 hours in vivo.

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eMolecules​ 111298-88-5 | [5-[tert-butyl(dimethyl)silyl]oxypentyl]magnesium bromide, 0.50 M in THF | Synthonix305.614 | C11H25BrMgOSi | 0.000 | [Br-].CC(C)(C)[Si](C)(C)OCCCCC[Mg+] | 100ml | 844919954

[5-[tert-butyl(dimethyl)silyl]oxypentyl]magnesium bromide, 0.50 M in THF | Synthonix | 111298-88-5305.614 | C11H25BrMgOSi | 0.000 | [Br-].CC(C)(C)[Si](C)(C)OCCCCC[Mg+] | 100ml | 844919954

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Medchemexpress LLC BI-4464 2 | 1227948-02-8 | 98.6% | 555.55 Da | C28H28F3N5O4 | 25MG

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BI-4464 is a selective ATP-competitive inhibitor of PTK2/FAK used as a research reagent for biochemical and cellular studies. It is provided with a reported purity of 98.64%, molecular formula C28H28F3N5O4, and a molecular weight of 555.55 Da. Intended for assay development, kinase profiling, and use as a ligand in targeted degradation studies; not for human or clinical use.

• High reported purity suitable for research applications.
• Selective ATP-competitive PTK2/FAK inhibition profile.
• Applicable to assay development and kinase profiling.
• Useful as a ligand in PROTAC and targeted degradation research.
• Available in multiple mg-scale quantities for laboratory use.
• Research use only; not intended for human or clinical use.

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eMolecules​ 312624-26-3 | 2-Cyanoethylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671974 | 199.360 | C3H4BrNZn | 0.000 | [Br-].[Zn+]CCC#N | 50ml | 532652678

2-Cyanoethylzinc bromide, 0.50 M in THF | Synthonix | 312624-26-3 | MFCD00671974 | 199.360 | C3H4BrNZn | 0.000 | [Br-].[Zn+]CCC#N | 50ml | 532652678

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eMolecules​ (Tetrahydrofuran-3-ylmethyl)magnesium bromide, 0.50 M in THF | Synthonix |189.335 | C5H9BrMgO | 0.000 | [Br-].[Mg+]CC1CCOC1 | 25ml | 794559330

(Tetrahydrofuran-3-ylmethyl)magnesium bromide, 0.50 M in THF | Synthonix |189.335 | C5H9BrMgO | 0.000 | [Br-].[Mg+]CC1CCOC1 | 25ml | 794559330

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eMolecules​ 9001-62-1 | Sustine? 131 | Strem Chemicals238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 100g | 576207973

Sustine? 131 | Strem Chemicals | 9001-62-1238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 100g | 576207973

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eMolecules​ 9001-62-1 | Sustine? 131 | Strem Chemicals238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 25g | 576207974

Sustine? 131 | Strem Chemicals | 9001-62-1238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 25g | 576207974

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eMolecules​ 51285-26-8 | Picolinimidamide hydrochloride | Ambeed | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 500g | 592282302

Picolinimidamide hydrochloride | Ambeed | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 500g | 592282302

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eMolecules​ 29671-92-9 | Chloroformamidine hydrochloride | Chem-Impex | MFCD00035527 | 114.960 | CH4Cl2N2 | 99.000 | Cl.NC(Cl)=N | 25g | 386903867

Chloroformamidine hydrochloride | Chem-Impex | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 99.000 | Cl.NC(Cl)=N | 25g | 386903867

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eMolecules​ 29671-92-9 | Chloroformamidine hydrochloride | Oakwood Chemicals | MFCD00035527 | 114.960 | CH4Cl2N2 | 97.000 | Cl.NC(Cl)=N | 25g | 480138805

Chloroformamidine hydrochloride | Oakwood Chemicals | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 97.000 | Cl.NC(Cl)=N | 25g | 480138805

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