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Filtered Search Results
Medchemexpress LLC Potassium 1,2-naphthoquinone-4-sulphonate | 5908-27-0 | 99.8% | 276.31 | C10H5KO5S | 100mg
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Potassium 1 2-naphthoquinone-4-sulphonate (Compound 16) is a 6-phosphogluconate dehydrogenase (6PGDH) inhibitor with an IC50 of 53 M Potassium 1 2-naphthoquinone-4-sulphonate can be used in the study of human African trypanosomiasis[1]
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eMolecules 189195-41-3 | 5-Methyl-2-(tributylstannyl)pyridine | Synthonix - Stock | MFCD07787402 | 382.179 | C18H33NSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1 | 500mg | 525920408
5-Methyl-2-(tributylstannyl)pyridine | Synthonix - Stock | 189195-41-3 | MFCD07787402 | 382.179 | C18H33NSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1 | 500mg | 525920408
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Apexbio Technology LLC BI-847325 1207293-36-4 100mg
BI-847325 (CAS 1207293-36-4) is a dual inhibitor targeting MEK1/2 and Aurora kinases with reported IC50 values of 25 nM and 4 nM against MEK1 and MEK2 and 3 nM 25 nM and 15 nM against Aurora A B and C respectively By inhibiting these kinases BI-847325 disrupts the MAPK/ERK and cell cycle signaling pathways that regulate cell proliferation and survival In cellular assays it demonstrates nanomolar EC50 values for inhibition of pERK and pHH3 in KRAS- and BRAF-mutant cancer cell lines and potently suppresses proliferation across a wide range of tumor cell models In xenograft studies it fully blocks tumor growth in BRAF- and KRAS-mutant cancer models This compound is utilized in research on kinase-targeted cancer therapies
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eMolecules Synthonix - Stock / 2-[(Tributylstannyl)methyl]-1H-isoindole-13(2H)-dione / 250mg / 525905195 / A1306 / / 144157-84-6 / [null] / 450.210 / C21H33NO2Sn
Synthonix - Stock / 2-[(Tributylstannyl)methyl]-1H-isoindole-13(2H)-dione / 250mg / 525905195 / A1306 / / 144157-84-6 / [null] / 450.210 / C21H33NO2Sn
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eMolecules 497923-83-8 | 2-Chloro-4-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260160 | 321.820 | C6H3ClFIZn | 0.000 | [I-].Fc1ccc([Zn+])c(Cl)c1 | 25ml | 627353544
2-Chloro-4-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 497923-83-8 | MFCD02260160 | 321.820 | C6H3ClFIZn | 0.000 | [I-].Fc1ccc([Zn+])c(Cl)c1 | 25ml | 627353544
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Medchemexpress LLC 4-Chloro-1-naphthol | 604-44-4 | 178.62 | 1 ML
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4-Chloro-1-naphthol is a substrate of horseradish peroxidase. It can be used to visualize protein bands in western blotting and immunohistochemical staining, and also as a substrate to stain cryosections black by indirect immunoperoxidase staining.
- Functions as a substrate for horseradish peroxidase
- Useful for visualizing protein bands in western blotting
- Applicable in immunohistochemical staining
- Can be used to stain cryosections black via indirect immunoperoxidase staining
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eMolecules 2987-06-6 | 4-(Benzyloxy)cyclohexanone | ChemScene | MFCD10697867 | 204.269 | C13H16O2 | 96.000 | O=C1CCC(CC1)OCc1ccccc1 | 25g | 582638620
4-(Benzyloxy)cyclohexanone | ChemScene | 2987-06-6 | MFCD10697867 | 204.269 | C13H16O2 | 96.000 | O=C1CCC(CC1)OCc1ccccc1 | 25g | 582638620
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AdipoGen 5-Hydroxynicotinic acid
Chemical. CAS 27828-71-3. Formula C6H5NO3. MW 139.11. Synthetic A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase MHPCO. Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
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eMolecules Synthonix 2-(Tributylstannyl)oxazole 250mg 659071661 T5598 145214-05-7 MFCD06798076 358.113 C15H29NOSn
Synthonix 2-(Tributylstannyl)oxazole 250mg 659071661 T5598 145214-05-7 MFCD06798076 358.113 C15H29NOSn
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eMolecules 170682-50-5 | 1-Methyl-5-(tributylstannyl)-1H-pyrazole | Synthonix - Stock | MFCD19686983 | 371.156 | C16H32N2Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccnn1C | 10g | 525921666
1-Methyl-5-(tributylstannyl)-1H-pyrazole | Synthonix - Stock | 170682-50-5 | MFCD19686983 | 371.156 | C16H32N2Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccnn1C | 10g | 525921666
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eMolecules 1213256-49-5 | 4-Chloro-2-methoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD11553187 | 245.780 | C7H6BrClMgO | 0.000 | [Br-].COc1cc(Cl)ccc1[Mg+] | 25ml | 437237052
4-Chloro-2-methoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 1213256-49-5 | MFCD11553187 | 245.780 | C7H6BrClMgO | 0.000 | [Br-].COc1cc(Cl)ccc1[Mg+] | 25ml | 437237052
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Medchemexpress LLC Ganfeborole hydrochl 100mg | 2131798-13-3 | 100MG
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Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) with an IC50 of 0 2 M
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Medchemexpress LLC Anagrelide hydrochloride | 58579-51-4 | MFCD01720337 | 99.4% | 1 ML
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Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) that inhibits platelet aggregation and bone marrow megakaryocytopoiesis. It has been shown to decrease gastrointestinal stromal tumor (GIST) cell proliferation and promote apoptosis in vitro. This imidazoquinazoline derivative acts as a platelet-lowering agent and exhibits antithrombopoietic action.
- Potent inhibitor of phosphodiesterase type III (PDE3) with an IC50 of 36 nM.
- Inhibits platelet aggregation.
- Inhibits bone marrow megakaryocytopoiesis.
- Decreases gastrointestinal stromal tumor (GIST) cell proliferation.
- Promotes apoptosis in vitro.
- Potently inhibits the development of marrow megakaryocytes (IC50=26 nM).
- Induces a cytotoxic effect in the GIST882 cell line (IC50=16 nM).
- Inhibits or reduces tumor growth in GIST2B, GIST9, and GIST882 models in vivo.
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eMolecules 71112-66-8 | (3-Phenanthryl)magnesium bromide, 0.25 M in THF | Synthonix281.435 | C14H9BrMg | 0.000 | [Br-].[Mg+]c1ccc2ccc3ccccc3c2c1 | 50ml | 818572036
(3-Phenanthryl)magnesium bromide, 0.25 M in THF | Synthonix | 71112-66-8281.435 | C14H9BrMg | 0.000 | [Br-].[Mg+]c1ccc2ccc3ccccc3c2c1 | 50ml | 818572036
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AdipoGen 1 4-Cubanebisdimethylamide
Chemical. CAS 133180-93-5. Formula C14H18N2O2. MW 246.3. Synthetic. Building block for synthesis.
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