Naphthalenes

Medchemexpress LLC Lofexidine hydrochloride | 21498-08-8 | 99.7% | 1 ML

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Lofexidine hydrochloride is a selective α2-receptor agonist, commonly used in research to alleviate the physical symptoms of opioid withdrawal. It is intended for research use only.

• Selective α2-receptor agonist
• Alleviates physical symptoms of opioid withdrawal
• For research use only
• Stable under recommended storage conditions
• Solid appearance

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Medchemexpress LLC NNC-711 hydrochloride | 145645-62-1 | MFCD00153853 | 99.8% | 386.87 g/mol | C21H23ClN2O3 | 1 ML

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NNC-711 (NO-711 hydrochloride) is a potent, selective inhibitor of the GABA transporter GAT-1 used in neuroscience research to modulate GABA uptake. It is supplied as a high-purity solid and as a 10 mM solution for laboratory use.

• Potent and selective GAT-1 inhibitor.
• High purity (≈99.8%).
• Available as solid powder and 10 mM solution.
• Molecular weight 386.87 g/mol; formula C21H23ClN2O3.
• Suitable for electrophysiology, GABA uptake assays, and in vivo pharmacology.
• Provided in research-scale quantities (mg ranges and 1 mL solution).

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Medchemexpress LLC 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide | 127625-29-0 | 100.0% | 425.52 g/mol | C23H24FN3O2S | 50 MG

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Fananserin is a selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist with activity at dopamine D4 receptors, supplied as a 50 mg powder for research use. It is used in pharmacological and neurological studies to probe 5-HT2A and D4 receptor function.

• High reported purity (≈99.97%).
• Molecular formula C23H24FN3O2S; molecular weight 425.52 g/mol.
• Soluble in DMSO: 100 mg/mL (ultrasonic).
• Powder form with recommended storage -20°C (3 years) or 4°C (2 years).
• Intended for research use only (RUO); not for human use.

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Medchemexpress LLC NNC 05-2090 hydrochloride | 184845-18-9 | MFCD00952020 | 99.1% | 451.00 g/mol | C27H31ClN2O2 | 100 MG

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NNC 05-2090 hydrochloride is a research compound that inhibits GABA uptake and selectively inhibits the mGAT2 (BGT-1) transporter. It exhibits anticonvulsant activity and is used in preclinical studies of epilepsy and other neurological disorders.

• GABA uptake inhibitor and selective mGAT2 (BGT-1) inhibitor (Ki ≈ 1.4 μM).
• Demonstrated anticonvulsant activity; used in preclinical epilepsy research.
• Supplied as the hydrochloride salt with molecular formula C27H31ClN2O2.
• High purity (99.1% by HPLC) suitable for biochemical and pharmacological studies.
• Available in multiple pack sizes and as a 10 mM solution in DMSO for in vitro use.

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Medchemexpress LLC BI-671800 | 1093108-50-9 | 99.4% | 501.50 | 1 ML

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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma.

• Hcrth2: 4.5 nM (IC50)
• Mcrth2: 3.7 μM (IC50)
• Exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
• Shows significant inhibition of AHR in mice at 0.1-10 mg/kg, i.g.
• Effectively blocks edema formation and greatly reduces inflammatory infiltrate and skin pathology observed in drug vehicle-treated animals.

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Medchemexpress LLC 2-METHYL-1-NAPHTHOL 500 mg

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2-METHYL-1-NAPHTHOL 500MG

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Medchemexpress LLC CEVIMELINE HYDROCHL 100 mg

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CEVIMELINE HYDROCHL 100MG

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Medchemexpress LLC 2,3-dimethoxy-1,4-naphthoquinone | 6956-96-3 | 99.8% | 10 MG

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DMNQ is a redox-cycling small molecule that produces hydrogen peroxide and increases intracellular reactive oxygen species (ROS). It is supplied as a solid powder for research use and is commonly used to model oxidative stress in cell-based assays.

• Redox-cycling agent that induces ROS production.
• Solid powder with formula C12H10O4 and molecular weight 218.21 g/mol.
• High purity suitable for research applications.
• Available in small milligram package sizes for laboratory use.
• Store powder at -20°C; store solutions at -80°C for long-term storage.

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