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Filtered Search Results
Medchemexpress LLC Glesatinib hydrochloride | 2319837-80-2 | 98.0% | 656.17 | 1 ML
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Glesatinib hydrochloride is an orally active, potent dual inhibitor of MET and SMO. This tyrosine kinase inhibitor also antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).
- Orally active and potent MET/SMO dual inhibitor.
- Tyrosine kinase inhibitor.
- Antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Prmt5-in-1 hydrochloride | 99.51% | 455.29 | 1 ML
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PRMT5 IN-1 hydrochloride, a hemiaminal, is a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 11 nM for the PRMT5/MEP50 complex. This compound can be converted to aldehydes and reacts with C449 to form covalent adducts under physiological conditions. As a hydrochloride salt, it typically offers enhanced water solubility and stability.
- Potent and selective inhibitor of PRMT5.
- Exhibits an IC50 of 11 nM for the PRMT5/MEP50 complex.
- Inhibits cellular sDMA in Granta-519 cells with an IC50 of 0.012 μM.
- Demonstrates antiproliferative activity in Granta-519 cells with an IC50 of 0.06 μM.
- Hydrochloride form provides enhanced water solubility and stability.
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Alkali Scientific 4 Chloro 1 Naphthol, 500 G
Chloro-naphthol is a versatile chromogenic reagent used in enzyme detection and blotting applications. This 500g bulk format is ideal for large-scale laboratory work, allowing researchers to prepare ample quantities of reagent for multiple assays. It is particularly useful in immunoassays, enzyme-linked immunosorbent assays (ELISA), and Western blotting, where it produces a visible color change in the presence of alkaline phosphatase activity. Chloro-naphthol is also commonly used in microbiological research to detect specific bacterial enzymes, aiding in microbial identification and enzymatic studies. This reagent is essential for accurate and sensitive enzyme detection in a wide range of laboratory protocols.
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eMolecules 27374-25-0 | (1-Ethoxycyclopropoxy)trimethylsilane | Aladdin Scientific Corporation | MFCD00074986 | 174.315 | C8H18O2Si | 98.000 | CCOC1(CC1)O[Si](C)(C)C | 25g | 845136997
(1-Ethoxycyclopropoxy)trimethylsilane | Aladdin Scientific Corporation | 27374-25-0 | MFCD00074986 | 174.315 | C8H18O2Si | 98.000 | CCOC1(CC1)O[Si](C)(C)C | 25g | 845136997
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Selleck Chemical LLC BI-D1870 S2843-1g
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays respectively 10- to 100-fold selectivity for RSK than MST2 GSK-3 MARK3 CK1 and Aurora B BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy
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eMolecules 932-31-0 | 2-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00010350 | 195.342 | C7H7BrMg | 0.000 | [Br-].Cc1ccccc1[Mg+] | 50ml | 437237316
2-Methylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 932-31-0 | MFCD00010350 | 195.342 | C7H7BrMg | 0.000 | [Br-].Cc1ccccc1[Mg+] | 50ml | 437237316
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1135389-59-1 | (1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.50 M in THF | Synthonix | MFCD07698709 | 232.380 | C4H7BrO2Zn | 0.000 | [Br-].[Zn+]CC1OCCO1 | 100ml | 532652737
(1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.50 M in THF | Synthonix | 1135389-59-1 | MFCD07698709 | 232.380 | C4H7BrO2Zn | 0.000 | [Br-].[Zn+]CC1OCCO1 | 100ml | 532652737
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Paroxetine (hydrochloride) | 78246-49-8 | 99.98% | 365.83 | 500 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor (SSRI), also known as a GRK2 inhibitor with an IC50 of 14 μM. It is commonly used for the research of depressive disorder.
- Potent selective serotonin-reuptake inhibitor
- GRK2 inhibitor with IC50 of 14 μM
- Used for research of depressive disorder
- Available in solid and solution forms
- High purity of 99.98%
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eMolecules 282727-20-2 | 2-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311442 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccccc1[Zn+] | 100ml | 532652889
2-Methoxyphenylzinc iodide, 0.50 M in THF | Synthonix | 282727-20-2 | MFCD01311442 | 299.420 | C7H7IOZn | 0.000 | [I-].COc1ccccc1[Zn+] | 100ml | 532652889
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 38858-90-1 | 4-Methyl-3-nitro-1H-pyrazole | Ambeed | MFCD09701703 | 127.103 | C4H5N3O2 | 97.000 | Cc1c[nH]nc1[N+]([O-])=O | 250mg | 490529939
4-Methyl-3-nitro-1H-pyrazole | Ambeed | 38858-90-1 | MFCD09701703 | 127.103 | C4H5N3O2 | 97.000 | Cc1c[nH]nc1[N+]([O-])=O | 250mg | 490529939
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 72136-49-3 | (9H-Fluoren-2-yl)magnesium bromide, 0.25 M in THF | Synthonix269.424 | C13H9BrMg | 95.000 | [Br-].[Mg+]c1ccc-2c(Cc3ccccc-23)c1 | 100ml | 818572020
(9H-Fluoren-2-yl)magnesium bromide, 0.25 M in THF | Synthonix | 72136-49-3269.424 | C13H9BrMg | 95.000 | [Br-].[Mg+]c1ccc-2c(Cc3ccccc-23)c1 | 100ml | 818572020
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eMolecules 322640-05-1 | 3,5-Dimethoxyphenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD08064086 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1cc([Mg+])cc(OC)c1 | 100ml | 437237136
3,5-Dimethoxyphenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 322640-05-1 | MFCD08064086 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1cc([Mg+])cc(OC)c1 | 100ml | 437237136
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eMolecules 15791-59-0 | 11,5-DIOXASPIRO[2.3]HEXANE(CONTAINS 16% BENZENE AND 42% DCM) | AstaTech | MFCD27940091 | 86.090 | C4H6O2 | 95.000 | C1OC11COC1 | 1g | 533506112
11,5-DIOXASPIRO[2.3]HEXANE(CONTAINS 16% BENZENE AND 42% DCM) | AstaTech | 15791-59-0 | MFCD27940091 | 86.090 | C4H6O2 | 95.000 | C1OC11COC1 | 1g | 533506112
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 37610-80-3 | 2-(1,3-Dioxolan-2-yl)ethylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD00061514 | 205.334 | C5H9BrMgO2 | 0.000 | [Br-].[Mg+]CCC1OCCO1 | 25ml | 702445879
2-(1,3-Dioxolan-2-yl)ethylmagnesium bromide, 0.50 M in THF | Synthonix | 37610-80-3 | MFCD00061514 | 205.334 | C5H9BrMgO2 | 0.000 | [Br-].[Mg+]CCC1OCCO1 | 25ml | 702445879
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eMolecules 46046-59-7 | Quinolin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix232.363 | C9H6BrMgN | 95.000 | [Br-].[Mg+]c1ccc2ccccc2n1 | 25ml | 702445981
Quinolin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix | 46046-59-7232.363 | C9H6BrMgN | 95.000 | [Br-].[Mg+]c1ccc2ccccc2n1 | 25ml | 702445981
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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