Naphthalenes
eMolecules Ambeed Silver(I) 222-trifluoroacetate 10g 490510326 A142227 2966-50-9 MFCD00013199 220.883 C2AgF3O2
Ambeed Silver(I) 222-trifluoroacetate 10g 490510326 A142227 2966-50-9 MFCD00013199 220.883 C2AgF3O2
Medchemexpress LLC Revaprazan (hydrochloride) | 178307-42-1 | 25 MG
Revaprazan hydrochloride is a reversible proton pump inhibitor that can inhibit gastric acid secretion and protect gastric mucosa. It can also inhibit IkappaB-alpha degradation and Akt inactivation, which attenuates H. pylori-induced COX-2 expression. This product can be used for research in infection and inflammation, including H. pylori-infected gastric inflammation and gastric ulcer.
- Reduces H. pylori-stimulated COX-2 expression and activity in AGS cells (5-20 μM, 24 h).
- Inhibits transcription activity of NF-κB in H. pylori-stimulated AGS cells (5-20 μM, 24 h).
- Improves the retarded cell growth in H. pylori-stimulated AGS cells (5-20 μM, 24 h).
Medchemexpress LLC Revaprazan (hydrochloride) | 178307-42-1 | 1 ML
Revaprazan hydrochloride is a reversible proton pump inhibitor. It inhibits gastric acid secretion and protects gastric mucosa. It can also inhibit IkappaB-alpha degradation and Akt inactivation, leading to the attenuation of H. pylori-induced COX-2 expression. This product is used for research on infections and inflammation, such as H. pylori-infected gastric inflammation and gastric ulcers.
- Reversible proton pump inhibitor
- Inhibits gastric acid secretion
- Protects gastric mucosa
- Attenuates H. pylori-induced COX-2 expression
- Reduces H. pylori-stimulated COX-2 expression and activity in AGS cells
- Inhibits transcription activity of NF-κB in H. pylori-stimulated AGS cells
- Improves retarded cell growth in H. pylori-stimulated AGS cells
- Used for research on infection and inflammation
AdipoGen Loxistatin acid
Chemical. CAS 76684-89-4. Formula C15H26N2O5. Molecular Weight 314.4. E-64c is a potent cell-impermeable epoxysuccinyl peptide inhibitor of calpain and other cysteine proteases, such as papain, cathepsin B, H and L. Does not inhibit the serine proteases trypsin, chymotrypsin or elastase. E-64c is an active metabolite of the protease inhibitor E-64d Prod. No. AG-CR1-3737, and a synthetic analog of E-64 Prod. No. AG-CP3-7006. Studies indicate that E-64c is a more potent inhibitor of cathepsins B and L compared to E-64. E-64c has in vitro antiviral, antiparasitic and immunomodulatory properties. It reduces the autocatalytic activity of the foot-and-mouth-disease virus FMDV leader protease, reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with SARS-CoV spike glycoprotein in a concentration-dependent manner, inhibits human rotavirus replication, and exhibits entry-blocking effects against MERS-CoV.
AdipoGen Loxistatin acid
Chemical. CAS 76684-89-4. Formula C15H26N2O5. Molecular Weight 314.4. E-64c is a potent cell-impermeable epoxysuccinyl peptide inhibitor of calpain and other cysteine proteases, such as papain, cathepsin B, H and L. Does not inhibit the serine proteases trypsin, chymotrypsin or elastase. E-64c is an active metabolite of the protease inhibitor E-64d Prod. No. AG-CR1-3737, and a synthetic analog of E-64 Prod. No. AG-CP3-7006. Studies indicate that E-64c is a more potent inhibitor of cathepsins B and L compared to E-64. E-64c has in vitro antiviral, antiparasitic and immunomodulatory properties. It reduces the autocatalytic activity of the foot-and-mouth-disease virus FMDV leader protease, reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with SARS-CoV spike glycoprotein in a concentration-dependent manner, inhibits human rotavirus replication, and exhibits entry-blocking effects against MERS-CoV.
Medchemexpress LLC Guanfacine (hydrochloride) | 29110-48-3 | 99.98% | 282.55 | 25 MG
Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist, highly selective for the α2A receptor subtype. It has effects in producing hypotension and sedation, and can be used for research on various prefrontal cortex (PFC) cognitive disorders, including Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).
- Orally active and blood-brain barrier permeable noradrenergic α2A agonist.
- High selectivity for the α2A receptor subtype.
- Increases delay-related neuronal firing needed for working memory on dIPFC neurons.
- Improves PFC cognitive function by inhibiting CAMP production, closing HCN channels, and strengthening PFC networks.
- Enhances PFC working memory function and improves impulse control in aged monkeys.
- Improves cognitive performance when infused directly into the rat or monkey PFC.
Medchemexpress LLC Guanfacine (hydrochloride) | 29110-48-3 | 100.0% | 282.55 | 100 MG
Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist, highly selective for the α2A receptor subtype. It has effects in producing hypotension and sedation, and can be used for research of various prefrontal cortex (PFC) cognitive disorders, including Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).
- Orally active and blood-brain barrier permeable
- Highly selective α2A receptor subtype agonist
- Produces hypotension and sedation
- Used for research on prefrontal cortex cognitive disorders
- Increases delay-related neuronal firing for working memory
- Improves PFC cognitive function
- Enhances PFC working memory in aged monkeys
- Improves impulse control in delayed discounting tasks
- Improves cognitive performance when infused into rat or monkey PFC