Unsubstituted Phenols
Sigma Aldrich Fine Chemicals Biosciences PhenolChloroformIso-amyl
PhenolChloroformIso-amyl alcohol (125241) is used for the purification of total RNA from mixtures of crude cell extracts and can eliminate the need for a time consuming ultracentrifugation step.
Apexbio Technology LLC Phenol Red sodium salt 34487-61-1 5g
Phenol Red sodium salt (34487-61-1) is a small molecule compound binding to estrogen receptors It can interact with estrogen receptors thereby modulating downstream signaling pathways and associated cellular processes Phenol Red sodium salt functions primarily via estrogen receptor affinity In cell-based studies it binds to estrogen receptors in human breast cancer cell lines such as MCF-7 cells Based on these properties Phenol Red sodium salt holds research potential in oncology studies particularly those investigating hormone-mediated signaling pathways and receptor-mediated cellular responses
Sigma Aldrich Fine Chemicals Biosciences TritonTM X 100 BioXtra
Triton(TM) X-100 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent non-denaturing and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection.
Apexbio Technology LLC Ko 143 461054-93-3 25mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Enzo Life Sciences Tyrphostin 25 (RG-50875) (5mg). CAS: 118409-58-8
A potent inhibitor of EGF receptor kinase activity (IC50=3 µM). Purity: ≥99%. Solubility: Soluble in 100% ethanol or DMSO. Long Term Storage: Ambient.
Enzo Life Sciences Tyrphostin 47 (RG-50864) (AG-213) (5mg). CAS: 122520-86-9
A potent inhibitor of EGF receptor kinase activity (IC50‘s:EGFR = 2.4 µM, PDGFR = 3.5 µM, p210bcr-abl=5.9 µM, insulin receptor = 640 µM). Purity: ≥99% (TLC). Solubility: Soluble at 20 mg/ml in 100% ethanol or DMSO. Long Term Storage: -20°C.
Medchemexpress LLC HY-N0619 5mg Medchemexpress, Mulberroside A CAS:102841-42-9 Purity:>98%
Medchemexpress, HY-N0619 5mg Mulberroside A CAS:102841-42-9 Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.) [1] . Mulberroside A decreases the expressions of TNF-α , IL-1β , and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects [2] . Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC 50 of 53.6 μM [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N1444 5mg Medchemexpress, Complanatuside CAS:116183-66-5 Purity:>98%
Medchemexpress, HY-N1444 5mg Complanatuside CAS:116183-66-5 Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-16950 50mg , 4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen;trans-4-Hydroxytamoxifen CAS:68047-06-3 Purity:98%
Medchemexpress, HY-16950 50mg 4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen;trans-4-Hydroxytamoxifen CAS:68047-06-3 Formula:C26H29NO2 IC50: 3.3 nM (Oestrogen receptor) CRISPR/Cas9 Purity:98% 4-Hydroxytamoxifen, an active metabolite of tamoxifen, is a selective estrogen receptor antagonist, with an IC 50 of 3.3 nM for the [ 3 H]oestradiol binding to oestrogen receptor, widely used to treat breast cancer; 4-Hydroxytamoxifen also increases CRISPR/Cas9 -mediated editing frequency. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N6628 50mg Medchemexpress, 6,2'-Dihydroxyflavone CAS:92439-20-8 Purity:>98%
Medchemexpress, HY-N6628 50mg 6,2'-Dihydroxyflavone CAS:92439-20-8 6,2'-Dihydroxyflavone is a novel antagonist of GABA A receptor . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.