Unsubstituted Phenols
Selleck Chemical LLC Cinitapride Hydrogen Tartrate
Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
Selleck Chemical LLC 2-Methoxybenzoic acid
2-Methoxybenzoic acid (o-Anisic acid) is a flavouring agent
eMolecules 1384268-04-5 | Medchem Express | SYP-5 | 5mg | 446255902 | HY-100693 | MFCD30534394 | 312.38 | C18H16O3S
ChemScene | Methyl 5-bromo-6-oxo-16-dihydropyridine-2-carboxylate | 250mg | 572233306 | CS-W006157 | 178876-86-3 | MFCD14698125 | 232.033 | C7H6BrNO3
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eMolecules 328565-16-8 | Medchem Express | Col003 | 5mg | 455326227 | HY-124817 | MFCD00852947 | 257.245 | C14H11NO4
AstaTech | TERT-BUTYL (1-METHYL-1H-PYRAZOL-4-YL)CARBAMATE | 0.25g | 386075499 | W18675 | 95.000 | 796845-64-2 | MFCD12031289 | 197.238 | C9H15N3O2
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Enzo Life Sciences Tyrphostin 1 (20mg). CAS: 2826-26-8
An inactive tyrphostin, which may be used as a negative control. Purity: ≥99%. Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml). Long Term Storage: Ambient.
Apexbio Technology LLC Ko 143 461054-93-3 10mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Apexbio Technology LLC Ko 143 461054-93-3 25mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Enzo Life Sciences Tyrphostin 25 (RG-50875) (5mg). CAS: 118409-58-8
A potent inhibitor of EGF receptor kinase activity (IC50=3 µM). Purity: ≥99%. Solubility: Soluble in 100% ethanol or DMSO. Long Term Storage: Ambient.
Medchemexpress LLC Nα,Nα-bis(carboxymethyl)-L-lysine | 113231-05-3 | MFCD00237437 | 98.8% | 262.26 | C10H18N2O6 | 10 G
Nα,Nα-Bis(carboxymethyl)-L-lysine is a research-grade small molecule that competitively inhibits the bitter taste receptor T2R4, with a reported IC50 of approximately 59 nM. It is used in receptor pharmacology and cell-based assays to probe T2R4-mediated signaling; in vitro studies show reduction of basal receptor activity, while limited in vivo effects on bitter taste behavior have been reported.
- Competitive inhibitor of bitter taste receptor 4 (IC50 ≈59 nM).
- Suitable for receptor pharmacology and cell-based assays.
- Shown in vitro to reduce basal activity of constitutively active T2R4 mutants.
- Reported minimal in vivo effect on bitter taste licking behavior at 10 μM.
- High purity material (98.8%) for research use.
- Molecular weight 262.26; formula C10H18N2O6.
Enzo Life Sciences Tyrphostin AG 1295 (5mg). CAS: 71897-07-9
PDGF inhibitor. Selective inhibitor of tyrosine kinase in platelet-derived growth factor (PDGF) receptor. Alternative name: 6,7-Dimethyl-2-phenylquinoxaline. Formula: C16H14N2. MW: 234.3. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C. Handling: Store tightly sealed in the dark. Protect from light.