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Filtered Search Results
Medchemexpress LLC Tyrphostin AG1296 | 146535-11-7 | 99.7% | 266.29 | 50 MG
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Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR) with an IC50 of 0.8 μM. It inhibits the signaling of human PDGF α- and β-receptors, as well as the related stem cell factor receptor (c-Kit). This compound also acts as a potent inhibitor of FLT3.
- Potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR)
- Inhibits human PDGF α- and β-receptors
- Targets stem cell factor receptor (c-Kit)
- Potent inhibitor of FLT3
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Medchemexpress LLC Isosilybin | 72581-71-6 | 482.44 | 50 MG
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Isosilybin is a flavonoid derived from Silybum marianum that functions as an inhibitor of CYP3A4 induction. It is intended for research use only.
- Inhibits PXR-mediated CYP3A4 induction with an IC50 of 74 μM.
- Acts as a stronger inhibitor of PXR-mediated CYP3A4 induction compared to silybin.
- Exhibits anti-prostate cancer activity through cell cycle arrest and apoptosis induction.
- Increases phosphorylation of Akt and Mdm2, associated with androgen receptor degradation.
- Enhances the formation of a complex between Akt, Mdm2, and AR.
- Can significantly activate PPARγ and causes transactivation of a PPARγ-dependent luciferase reporter.
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STA Pharmaceutical Fmoc-(S)-3-Amino-3-(2,4-dichlorophenyl)-propionic acid | 1 g | CAS 501015-34-5 | MDL MFCD03427980
Fmoc-(S)-3-Amino-3-(2,4-dichlorophenyl)-propionic acid is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 501015-34-5
- MDL: MFCD03427980
- InChIKey: GQCANHDOGYQXNY-QFIPXVFZSA-N
- Molecular Weight: 456.319
- Molecular Formula: C24H19Cl2NO4
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid
- SMILES: O=C(C[C@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C4=C(C=C(C=C4)Cl)Cl)O
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Medchemexpress LLC HY-N1939 5mg Medchemexpress, Icariside I CAS:56725-99-6 Purity:>98%
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Medchemexpress, HY-N1939 5mg Icariside I CAS:56725-99-6 Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Branaplam hydrochloride | 1562338-39-9 | 99.4% | 429.94 | 100 MG
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Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective, and orally active survival motor neuron-2 (SMN2) splicing modulator. It has an EC50 of 20 nM for SMN and inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. This compound is capable of elevating full-length SMN protein and has been shown to extend survival in a severe spinal muscular atrophy (SMA) mouse model.
- Highly potent, selective, and orally active
- SMN2 splicing modulator
- Elevates full-length SMN protein
- Extends survival in a severe spinal muscular atrophy (SMA) mouse model
- Inhibits hERG with an IC50 of 6.3 μM
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Medchemexpress LLC HY-10303 5mg Medchemexpress, PIK-294 CAS:900185-02-6 Purity:>98%
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Medchemexpress, HY-10303 5mg PIK-294 CAS:900185-02-6 PIK-294 is a potent p110δ-selective inhibitor with an IC50 of 10 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 102212-26-0 | Medchem Express | ARN2966 | 5mg | 446268991 | HY-18292 | MFCD24550644 | 200.241 | C12H12N2O
Medchem Express | Maprotiline (hydrochloride) | 100mg | 446272751 | HY-B0444 | 10347-81-6 | 313.870 | C20H24ClN
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Medchemexpress LLC (+)-Secoisolariciresinol | 145265-02-7 | 5 MG
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(+)-Secoisolariciresinol is a lignan compound and a (+)-enantiomer of Secoisolariciresinol. It is intended for research use only.
- Purity of 99.66%
- Molecular weight: 362.42
- Chemical formula: C20H26O6
- Appearance: solid
- Color: white to off-white
- Soluble in DMSO (requires sonication)
- Compatible with various in vivo dissolution protocols
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eMolecules 588-05-6 | 3-(2-Amino-ethyl)-phenol | J & W PharmLab LLC | MFCD06654561 | 137.182 | C8H11NO | 96.000 | NCCc1cccc(O)c1 | 5g | 289350884
3-(2-Amino-ethyl)-phenol | J & W PharmLab LLC | 588-05-6 | MFCD06654561 | 137.182 | C8H11NO | 96.000 | NCCc1cccc(O)c1 | 5g | 289350884
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Medchemexpress LLC Miquelianin (Quercetin 3-O-glucuronide) | 22688-79-5 | 99.9% | 478.36 | 100 MG
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Miquelianin (Quercetin 3-O-glucuronide) is a natural flavonoid and a metabolite of quercetin. It acts as a CBR1 inhibitor and is capable of crossing the blood-brain barrier.
- Metabolite of quercetin and natural flavonoid
- Functions as a CBR1 inhibitor
- Permeable to the blood-brain barrier
- Exhibits antioxidant effects in human plasma
- Reduces β-amyloid (Aβ) peptides generation
- Interferes with initial protein-protein interaction of Aβ1-40 and Aβ1-42
- Suppresses ROS generation and signaling pathways
- Inhibits invasion of breast cancer cells
- May act as a dietary chemopreventive factor
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Medchemexpress LLC Terbutaline (sulfate) | 23031-32-5 | 100.0% | 500 MG
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Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol. It is primarily used in asthma symptom research.
- Acts as an orally active β2-adrenergic receptor agonist.
- Functions as an active metabolite of bambuterol.
- Enhances MKP-1 expression in activated mouse macrophages.
- Reduces the phosphorylation of p38 MAPK in J774 macrophages.
- Improves allodynia in ob/ob mice.
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Medchemexpress LLC 7,4'-dihydroxyflavone | 2196-14-7 | MFCD00017694 | 99.6% | 254.24 g/mol | C15H10O4 | 10 MG
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7,4'-Dihydroxyflavone is a flavone-class small molecule used in biochemical and pharmacological research. It is supplied as a solid powder and as a DMSO solution for in vitro studies, and is commonly used to probe signaling pathways and enzyme activity. The compound has defined chemical identity (CAS 2196-14-7) and high reported purity, making it suitable for screening and mechanistic experiments.
- Small-molecule flavone for in vitro research.
- Available as solid powder and as a DMSO solution for convenient dosing.
- High reported purity suitable for biochemical assays.
- Used to modulate signaling pathways and enzyme activity in mechanistic studies.
- Defined chemical identifiers provided for traceability and documentation.
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Medchemexpress LLC HY-103638 250mg Medchemexpress, 3-Methoxytyramine (hydrochloride) CAS:1477-68-5 Purity:>98%
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Medchemexpress, HY-103638 250mg 3-Methoxytyramine (HCl) CAS:1477-68-5 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem 2 4-Bis(trifluoromethyl)phenol | ≥97% | CAS 908848-70-4 | C8H4F6O | 250mg
2 4-Bis(trifluoromethyl)phenol | ≥97% | CAS 908848-70-4 | C8H4F6O | 250mg
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Aobchem 2-Bromo-6-(tert-butyl)phenol | ≥95% | CAS 23159-87-7 | C10H13BrO | 500mg
2-Bromo-6-(tert-butyl)phenol | ≥95% | CAS 23159-87-7 | C10H13BrO | 500mg
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