Organic phosphoric acids and derivatives
Medchemexpress LLC Trisodium phosphate dodecahydrate | 10101-89-0 | MFCD00149198 | 98.1% | 380.12 g/mol | Na3PO4 · 12H2O | 1 KG
Trisodium phosphate dodecahydrate is an inorganic, research-grade salt used as a corrosion inhibitor, pH regulator, buffer component, and pharmaceutical excipient. It is provided as a crystalline hydrate with a listed assay of 98.1% and is offered in multiple pack sizes including 1 kg.
- Corrosion inhibitor for iron in aqueous systems.
- Functions as a pH regulator and buffer component.
- Available in multiple pack sizes for laboratory use.
- Supplied as a crystalline dodecahydrate (hydrated form).
Cayman Chemical DIhexadecyl Phosphate 10g
A synthetic phospholipid; has been used to impart a negative charge to neutral liposomes; has been used in the generation of micelles, liposomes, and other types of artificial membranes, including niosomes for drug delivery
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 200mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 99.5% | 611.51 g/mol | C26H29F3N5O7P | 25 MG
Uzansertib phosphate is the phosphate salt of Uzansertib (INCB053914), an orally active, ATP-competitive pan-PIM kinase inhibitor used in preclinical research to probe PIM kinase signaling, inhibit proliferation in hematologic cancer cell lines, and reduce tumor growth in animal models.
- Orally active, ATP-competitive pan-PIM kinase inhibitor.
- Low-nanomolar activity against PIM1, PIM2, and PIM3 (PIM1 0.24 nM; PIM2 30 nM; PIM3 0.12 nM).
- High purity solid, about 99.5% by LCMS.
- Suitable for in vitro and in vivo studies of PIM signaling and downstream phosphorylation (p70S6K/S6, 4E-BP1, BAD).
- White to off-white solid; molecular weight 611.51 g/mol; formula C26H29F3N5O7P.
Aobchem N N-diethyl-3 5-dimethylbenzamide | 95% | CAS 15930-57-1 | C13H19NO | 1g
N N-diethyl-3 5-dimethylbenzamide | 95% | CAS 15930-57-1 | C13H19NO | 1g
Medchemexpress LLC Vidarabine phosphate | 29984-33-6 | 99.4% | 50 MG
Vidarabine phosphate (Ara-AMP) is an antiviral agent that inhibits chronic HBV infection. It is also effective against herpes simplex and varicella zoster viruses.
- Antiviral agent
- Inhibits chronic HBV infection
- Active against herpes simplex and varicella zoster viruses
- For research use only
Apexbio Technology LLC Diethyl phosphate 598-02-7 100mg
Diethyl phosphate (CAS 598-02-7) is an organophosphorus compound commonly detected as a metabolic or degradation product of various organophosphate insecticides such as chlorpyrifos While diethyl phosphate itself exhibits low acute toxicity it serves as an important biomarker for organophosphate exposure in environmental and biological monitoring studies The compound does not act via acetylcholinesterase inhibition unlike its parent compounds instead its presence reflects the extent of exposure and metabolic processing of organophosphate pesticides Diethyl phosphate is widely utilized in toxicological environmental and epidemiological research to assess pesticide exposure levels
Medchemexpress LLC Histamine phosphate | 51-74-1 | 99.3% | C5H15N3O8P2 | 5 G
Histamine phosphate, also known as Histamine diphosphate, is a potent agonist for the histamine receptor and functions as a vasodilator. This organic nitrogen compound plays a crucial role in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. It affects the p38 MAPK/Akt signaling pathway and exhibits various biological activities including antitumor, antioxidant, and anti-inflammatory properties, making it valuable in research for conditions like acute myeloid leukemia, malignant melanoma, and renal cell carcinoma.
- Regulates MDA-MB-231 cell proliferation, inducing cell cycle arrest, lipid droplet formation, differentiation, and apoptosis.
- Increases reactive oxygen species (ROS) generation and enhances radiosensitivity in MDA-MB-231 cells.
- Inhibits microglia migration and IL-1β release in LPS-stimulated N9 cells, demonstrating anti-inflammatory effects.
Apexbio Technology LLC Naphthoquine phosphate 173531-58-3 5mg
Naphthoquine phosphate (CAS 173531-58-3) is an antimalarial agent targeting multiple isolates of Plasmodium falciparum In in vitro studies naphthoquine phosphate demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 to 5 2 nM Enhanced efficacy was observed in animal models infected with Plasmodium knowlesi when naphthoquine phosphate was administered in combination with artemisinin In clinical trials involving adult patients with uncomplicated P falciparum malaria an oral single-dose regimen of naphthoquine phosphate and artemisinin led to parasite clearance within an average of 34 6 14 3 hours Based on these pharmacological properties naphthoquine phosphate holds research potential in antimalarial drug resistance and combination therapy strategies
Apexbio Technology LLC KN-92 phosphate 1135280-28-2 10mg
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions