Organic sulfonic acids and derivatives
1-Hexanesulfonic acid, sodium salt hydrate, 98%, HPLC grade
CAS: 2832-45-3 Molecular Formula: C6H13NaO3S Molecular Weight (g/mol): 188.22 MDL Number: MFCD00007542 InChI Key: QWSZRRAAFHGKCH-UHFFFAOYSA-M Synonym: sodium 1-hexanesulfonate,sodium hexane-1-sulfonate,sodium hexanesulfonate,1-hexanesulfonic acid sodium salt,1-hexanesulfonic acid, sodium salt,1-hexanesulfonic acid, sodium salt 1:1,1-hexane sulfonic acid sodium salt,hexyl sodium sulfonate,1-hexanesulfonate, sodium,hexanesulfonic acid na-salt PubChem CID: 23677630 IUPAC Name: sodium;hexane-1-sulfonate SMILES: [Na+].CCCCCCS([O-])(=O)=O
1,3-Propane sultone, MP Biomedicals™
CAS: 1120-71-4 Molecular Formula: C3H6O3S Molecular Weight (g/mol): 122.14 MDL Number: MFCD00005355 InChI Key: FSSPGSAQUIYDCN-UHFFFAOYSA-N Synonym: 1,3-propanesultone,propane sultone,1,2-oxathiolane 2,2-dioxide,1,3-propane sultone,1,2-oxathiolane, 2,2-dioxide,propanesultone,rcra waste number u193,.gamma.-propane sultone,3-hydroxy-1-propanesulfonic acid gamma-sultone,unii-l6ntk7vjx9 PubChem CID: 14264 ChEBI: CHEBI:82370 IUPAC Name: 1,2λ⁶-oxathiolane-2,2-dione SMILES: O=S1(=O)CCCO1
1-Butanesulfonic acid, sodium salt, 99+%, HPLC grade
CAS: 2386-54-1 Molecular Formula: C4H9NaO3S Molecular Weight (g/mol): 160.16 MDL Number: MFCD00007540 InChI Key: XQCHMGAOAWZUPI-UHFFFAOYSA-M Synonym: sodium 1-butanesulfonate,sodium butane-1-sulfonate,1-butanesulfonic acid sodium salt,sodium butylsulfonate,1-butanesulfonic acid, sodium salt,sodium butane-1-sulphonate,sodium butanesulfonate,ipc-alks-4,1-butanesulfonic acid, sodium salt 1:1,acmc-1cdot PubChem CID: 4096517 IUPAC Name: sodium;butane-1-sulfonate SMILES: [Na+].CCCCS([O-])(=O)=O
1-Pentanesulfonic acid, sodium salt monohydrate, 98+%, HPLC grade
CAS: 207605-40-1 Molecular Formula: C5H11NaO3S·H2O Molecular Weight (g/mol): 192.22 MDL Number: MFCD00149548 InChI Key: FPQYXAFKHLSWTI-UHFFFAOYSA-M Synonym: sodium pentane-1-sulfonate hydrate,1-pentanesulfonic acid sodium salt monohydrate,sodium 1-pentanesulfonate monohydrate,potassium hydrate pentane-1-sulfonate,sodium 1-pentanesulfonate hydrate,sodium hydrate pentane-1-sulfonate,sodium pentane-1-sulfonate-water 1/1/1,1-pentane sulphonic acid sodium salt monohydrate,1-pentanesulfonic acid sodium salt monohydydrate,sodium 1-pentanesulfonate monohydrate, hplc grade PubChem CID: 23693099 IUPAC Name: sodium;pentane-1-sulfonate;hydrate SMILES: CCCCCS(=O)(=O)[O-].O.[Na+]
Sigma Aldrich Fine Chemicals Biosciences Taurine suitable for cell culture|107-35-7 | MFCD00008197 | 100g
Taurine suitable for cell culturePurity: | MW: 125.15 | 107-35-7 | MFCD00008197 | 100g
Sigma Aldrich Fine Chemicals Biosciences Taurine | 107-35-7 | MFCD17169940 | 25g
TaurinePurity: | MW: 125.15 | 107-35-7 | MFCD00008197 | 25g
Medchemexpress LLC Pulrodemstat benzenesulfonate | 2097523-60-7 | 99.6% | 50 MG
Pulrodemstat benzenesulfonate is a potent, selective, reversible, and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. It induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells, demonstrating potent anticancer activity.
- Potent, selective, reversible, and orally active LSD1 inhibitor
- Less enzymatic inhibition against LSD2, MAO-A, and MAO-B
- Induces differentiation in AML and SCLC cells
- Demonstrates potent anticancer activity
- Shows potent induction of CD11b in THP-1 cell line
- Exhibits antiproliferative activity in AML kasumi-1 cells
- Suppression of GRP observed in a dose-dependent manner
- Potent antiproliferative activity in SCLC cells
Medchemexpress LLC ASN007 benzenesulfonate (ERK-IN-3 benzenesulfonate) | 2055597-39-0 | 99.7% | 632.11 | 100 MG
ASN007 (ERK-IN-3) benzenesulfonate is a potent and orally active inhibitor of ERK. It demonstrates potent inhibition of ERK1/2 with low single-digit nanomolar IC50 values. This compound exhibits significant antiproliferative activity against various tumor cells and is suitable for research into cancers driven by RAS mutations.
- Potent and orally active ERK inhibitor
- Inhibits ERK1/2 with low single-digit nM IC50 values
- Exhibits significant antiproliferative activity against various tumor cells
- Useful for research of cancers driven by RAS mutations
- Inhibits the phosphorylation of ERK1/2 substrates (e.g., RSK1, FRA1, Elk1) in various cell lines
- Induces G0/G1 phase cell cycle arrest in various cells
- Significantly inhibits tumor growth and shows good tolerance in nude mice bearing BRAF and KRAS mutant xenograft tumors
Medchemexpress LLC Pulrodemstat benzenesulfonate | 2097523-60-7 | 99.6% | 10 MG
Pulrodemstat benzenesulfonate (CC-90011) is a potent, selective, reversible, and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. It exhibits less enzymatic inhibition against LSD2, MAO-A, and MAO-B. This compound induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells and demonstrates potent anticancer activity.
- Potent, selective, reversible, and orally active LSD1 inhibitor
- IC50 of 0.25 nM for LSD1
- Induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell differentiation
- Potent anticancer activity
- Less enzymatic inhibition against LSD2, MAO-A, and MAO-B
Apexbio Technology LLC PF-06424439-methanesulfonate
PF-06424439 methanesulfonate (CAS No 1469284-79-4) is a compound under investigation in biomedical research primarily within the category of oncology It originates from medicinal chemistry efforts to develop novel therapeutics targeting specific cellular pathways involved in cancer progression Its mechanism of action involves inhibition of key kinases disrupting signaling pathways crucial for tumor cell proliferation and survival This compound demonstrates in vitro activity typically in the nanomolar to low micromolar range indicating potent efficacy against targeted cancer cells Common applications include studies in cancerous cell models and preclinical animal studies to evaluate therapeutic potential Additionally it plays a role in drug screening processes to identify promising candidates for further development Experimental concentrations typically depend on the specific research design employed in these studies
Apexbio Technology LLC PF-06424439-methanesulfonate
PF-06424439 methanesulfonate (CAS No 1469284-79-4) is a compound under investigation in biomedical research primarily within the category of oncology It originates from medicinal chemistry efforts to develop novel therapeutics targeting specific cellular pathways involved in cancer progression Its mechanism of action involves inhibition of key kinases disrupting signaling pathways crucial for tumor cell proliferation and survival This compound demonstrates in vitro activity typically in the nanomolar to low micromolar range indicating potent efficacy against targeted cancer cells Common applications include studies in cancerous cell models and preclinical animal studies to evaluate therapeutic potential Additionally it plays a role in drug screening processes to identify promising candidates for further development Experimental concentrations typically depend on the specific research design employed in these studies
Apexbio Technology LLC PF-06424439-methanesulfonate
PF-06424439 methanesulfonate (CAS No 1469284-79-4) is a compound under investigation in biomedical research primarily within the category of oncology It originates from medicinal chemistry efforts to develop novel therapeutics targeting specific cellular pathways involved in cancer progression Its mechanism of action involves inhibition of key kinases disrupting signaling pathways crucial for tumor cell proliferation and survival This compound demonstrates in vitro activity typically in the nanomolar to low micromolar range indicating potent efficacy against targeted cancer cells Common applications include studies in cancerous cell models and preclinical animal studies to evaluate therapeutic potential Additionally it plays a role in drug screening processes to identify promising candidates for further development Experimental concentrations typically depend on the specific research design employed in these studies
Medchemexpress LLC Diphenylamine hydrochloride | 537-67-7 | 1 G
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and shares a common structure with non-steroidal anti-inflammatory drugs (NSAIDs). It functions by uncoupling oxidative phosphorylation in mitochondria, which can lead to a decrease in hepatic cell ATP levels and potential liver cell damage. Additionally, it serves as an industrial antioxidant, a dyeing mordant, and finds use in agriculture as both an antifungal and antibacterial agent.
- Antihyperglycemic agent with oral activity
- Functions as an industrial antioxidant
- Acts as a dyeing mordant
- Used as an antifungal agent in agriculture
- Used as an antibacterial agent in agriculture
- Uncouples oxidative phosphorylation in mitochondria
- Leads to decreased hepatic cell ATP levels
Medchemexpress LLC Flavanomarein | 577-38-8 | 5 MG
Flavanomarein is a substance with cytoprotective, anti-inflammatory, and antioxidant activities. It enhances the phosphorylation level of AKT, regulates various protein expressions, and inhibits nuclear translocation of NF-κB p65. It also protects neuronal cells from damage and is applicable for studies related to Parkinson's disease and diabetic nephropathy.
- Exhibits cytoprotective, anti-inflammatory, and antioxidant activities
- Enhances the phosphorylation level of AKT
- Regulates expression of PKC-δ, P85α, PKC-β1, Sirt1, Bcl-2, and ICAD
- Inhibits the nuclear translocation of NF-κB p65
- Regulates EMT marker proteins
- Promotes the proliferation of HK-2 cells
- Protects neuronal cells from 6-OHDA-induced neurotoxic damage
- Applicable for studies related to Parkinson's disease and diabetic nephropathy
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