Vinylogous acids
Sigma Aldrich 4-Hydroxy-2,5-dimethyl-3(2H)-furanone
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-(3-methylphenyl)-2-morpholin-4-ylethanamine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Guanine hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Fine Chemicals Biosciences 4-Hydroxy-6-methyl-2-pyrone 98% | 675-10-5 | MFCD00006641 | 5G
4-Hydroxy-6-methyl-2-pyrone 98% | Purity: 98% | Mol Wt: 126.11 | 675-10-5 | MFCD00006641 | 5G
Medchemexpress LLC 2R 3R-E1R 10mg | 1400888-63-2 | 232.28 | C13H16N2O2 | 10 MG
(2R,3R)-E1R is the (2R,3R) enantiomer of E1R and a sigma-1 receptor positive allosteric modulator (Sig1R PAM) supplied for research use. It is intended for in vitro and preclinical studies investigating cognition and memory disorders and is not for human or clinical use.
- Sigma-1 receptor positive allosteric modulator for cognition and memory research.
- High chemical purity: 98.8% and enantiomeric excess 99.6%.
- Chemical formula C13H16N2O2, molecular weight 232.28.
- Available in small milligram packages (for example, 10 MG).
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
Medchemexpress LLC Boc-val-cit-pab-pnp | 870487-10-8 | 99.6% | 644.67 | C30H40N6O10 | 50 MG
Boc-Val-Cit-PAB-PNP is a protease-cleavable linker used to construct antibody-drug conjugates (ADCs). It releases payloads after intracellular proteolytic cleavage and is supplied as a solid with high purity.
- Cleavable val-cit peptide linker releasing payload upon proteolysis
- Para-aminobenzyl spacer with p-nitrophenyl leaving group
- High purity suitable for research applications
- Soluble in DMSO at 100 mg/mL with ultrasonic assistance
- Recommended storage: -20°C under nitrogen; in solvent store at -80°C for long-term
- Available in small research scales, e.g. 50 mg
Medchemexpress LLC Dehydroepiandrosterone sulfate | 651-48-9 | 99.9% | 368.49 | 10 MG
Dehydroepiandrosterone sulfate | 651-48-9 | 99.9% | 368.49 | 10 MG
Medchemexpress LLC FTISADTSK acetate | 99.7% | 1029.10 | 5 MG
FTISADTSK acetate is an endogenous stable signature peptide derived from Trastuzumab. It is specifically monitored by selected reaction monitoring (SRM) and is intended solely for research applications.
- Endogenous stable signature peptide
- Monitored by selected reaction monitoring (SRM)
- Suitable for research use only
- Solid appearance, ranging from white to light brown
- Molecular weight: 1029.10
- Chemical formula: C44H72N10O18
- Soluble in water at 50 mg/mL (48.59 mM), may require sonication
- Powder storage: -80°C for 2 years or -20°C for 1 year
- Solution storage: -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Ships at room temperature within the continental US
eMolecules 87-13-8 | Ethyl ethoxymethylene malonate | Oakwood Chemical | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906
Ethyl ethoxymethylene malonate | Oakwood Chemical | 87-13-8 | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | 4077-47-8 | MFCD00209504 | 100G
2,5-Dimethyl-4-methoxy-3(2H)-furanone natural, >=98%, FG | Purity: >=98% | Mol Wt: 142.15 | 4077-47-8 | MFCD00209504 | 100G
Medchemexpress LLC Adenylosuccinic acid tetraammonium | >98% | 10 MG
Adenylosuccinic acid tetraammonium is an orally active purine ribonucleoside monophosphate involved in nucleotide cycle metabolism. This compound can be converted into fumaric acid via adenylosuccinate lyase and holds potential for the study of Duchenne muscular dystrophy (DMD).
- Orally active purine ribonucleoside monophosphate
- Plays a role in nucleotide cycle metabolism
- Converts into fumaric acid via adenylosuccinate lyase
- Potential for Duchenne muscular dystrophy (DMD) research
- Ameliorates murine Duchenne muscular dystrophy symptoms in vivo
eMolecules 571-55-1 | Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate | Oakwood Chemical | MFCD00052716 | 240.178 | C9H11F3O4 | 96.000 | CCO\C=C(/C(=O)OCC)C(=O)C(F)(F)F | 1g | 537669984
Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate | Oakwood Chemical | 571-55-1 | MFCD00052716 | 240.178 | C9H11F3O4 | 96.000 | CCO\C=C(/C(=O)OCC)C(=O)C(F)(F)F | 1g | 537669984
Medchemexpress LLC VU0810464 | 2126040-21-7 | 99.3% | 50 MG
VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.
- Potent and selective activator of GIRK (Kir3) channels
- Displays nanomolar potency for neuronal and GIRK1/4 channels
- Exhibits improved brain penetration
- Reduces stress-induced hyperthermia (SIH) in mice
![Medchemexpress LLC 6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline | 927691-21-2 | MFCD12828216 | >98.0% | 403.43 | C22H21N5O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298370.png-250.jpg)
Medchemexpress LLC 6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline | 927691-21-2 | MFCD12828216 | >98.0% | 403.43 | C22H21N5O3 | 10 MG
PQ-10 (6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline) is a selective phosphodiesterase 10A (PDE10A) inhibitor provided as a research reagent. It demonstrates low-nanomolar in vitro potency and has been used in preclinical studies to probe PDE10A-related signaling and brain glucose metabolism. For research use only; not for human or clinical use.
- Selective PDE10A inhibitor with low-nanomolar potency.
- Reported in vivo activity supporting preclinical studies.
- Chemical identity: C22H21N5O3, molecular weight 403.43.
- Supplied in small research quantities (example: 10 mg).
- For research use only; not intended for human use.