Azepines
Aobchem 4-(3-(Tert-butyl)phenyl)tetrahydro-2H-pyran-4-ol | 97% | CAS 1353499-65-6 | C15H22O2 | 500mg
4-(3-(Tert-butyl)phenyl)tetrahydro-2H-pyran-4-ol | 97% | CAS 1353499-65-6 | C15H22O2 | 500mg
Apexbio Technology LLC CARBAMAZEPINE-D10-5MG
Carbamazepine-d10 (CAS No 132183-78-9) is a deuterated form of carbamazepine primarily used in biomedical research as a stable isotope-labeled internal standard It originates from the anticonvulsant drug carbamazepine which targets voltage-gated sodium channels inhibiting repetitive neuronal firing In vitro activities are generally observed in the nanomolar to low micromolar range making it useful for precise pharmacokinetic and bioavailability studies Typical applications include studying metabolic pathways in cell models and examining drug interactions in animal studies Additionally it assists in drug screening assays ensuring accurate quantification Experimental concentrations typically depend on the specific research design
Cayman Chemical CarbamazepIn 10g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Medchemexpress LLC N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester | 286961-15-7 | 98.59% | 343.23 | 5 G
N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent. It is intended solely for research purposes and not for sale to patients. This compound is a solid with a white to off-white appearance.
- High purity (98.59%)
- Suitable for biochemical research
- Long-term storage stability as powder and in solvent
- Consistent with structure by 1H NMR and LCMS
TARGETMOL CHEMICALS INC Eslicarbazepine 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures. Purity 99.23%
Medchemexpress LLC Carbamazepine (standard) | 298-46-4 | 99.97% | 50 MG
Carbamazepine (Standard) is an orally active, pressure-sensitive sodium ion channel blocker, demonstrating an IC50 of 131 μM. This compound also blocks voltage-gated Na+, Ca2+, and K+ channels, and acts as a histone deacetylase (HDAC) inhibitor with an IC50 of 2 μM. It is primarily used as an anticonvulsant in research settings. This analytical standard is suitable for qualitative, quantitative, and methodological research experiments, including applications in HPLC, GC, and MS.
- Functions as an anticonvulsant for epilepsy and neuropathic pain research.
- Blocks voltage-gated sodium, calcium, and potassium channels.
- Inhibits histone deacetylase (HDAC).
- Supplied as an analytical standard for various research applications.
Cayman Chemical CarbamazepIn 25g
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Medchemexpress LLC Carbamazepine | 298-46-4 | MFCD00005073 | 99.95% | 1 ML
Carbamazepine is an orally active sodium ion channel blocker and HDAC inhibitor. It is used for research related to epilepsy and neuropathic pain, blocking voltage-gated Na+, Ca2+, and K+ channels. Its anticonvulsant properties make it suitable for various neurological studies.
- Orally active sodium ion channel blocker
- HDAC inhibitor with IC50 of 2 μM
- Blocks voltage-gated Na+, Ca2+, and K+ channels
- Used in epilepsy and neuropathic pain research
- Anticonvulsant properties
Aobchem 4-(2-(Methylthio)phenyl)tetrahydro-2H-pyran-4-ol | 95% | CAS 2918907-75-0 | C12H16O2S | 250mg
4-(2-(Methylthio)phenyl)tetrahydro-2H-pyran-4-ol | 95% | CAS 2918907-75-0 | C12H16O2S | 250mg
Aobchem 3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 1g
3-(2-(Methylthio)phenyl)tetrahydrofuran-3-ol | 95% | CAS 2969358-14-1 | C11H14O2S | 1g
Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 1 ML
Oxcarbazepine (GP 47680) is an anti-epileptic agent that functions as a sodium channel blocker. It significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It exhibits both anti-cancer and anticonvulsant effects.
- Inhibits glioblastoma cell growth with IC50 values of 12.35 μg/mL for U87 cell lines and 9.45 μg/mL for T98 cell lines.
- Protects mice and rats against generalized tonic-clonic seizures induced by electroshock.
- No tolerance to anticonvulsant effect observed in rats treated daily for 4 weeks.
- Functions as a sodium channel blocker.
- Induces apoptosis or G2/M arrest in glioblastoma cell lines.