Azetidines
Medchemexpress LLC Azetidine-3-carboxylic acid | 36476-78-5 | MFCD00191763 | 101.10 | C4H7NO2 | 10 G
Azetidine-3-carboxylic acid is a small heterocyclic carboxylic acid used as a building block in medicinal and linker chemistry, including applications in ADC and PROTAC synthesis.
- Small four-membered heterocyclic carboxylic acid building block.
- Used in linker and medicinal chemistry, including ADC and PROTAC synthesis.
- Physical form: powder suitable for storage under recommended conditions.
- Molecular formula C4H7NO2 and molecular weight 101.10.
- Storage stability: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 25 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline, found in common beets. It can be misincorporated into proteins in place of proline in many species, including humans, and is considered a toxic and teratogenic agent. This compound is intended for research use only.
- Non-proteinogenic amino acid homologue of proline
- Found in common beets
- White to off-white solid appearance
- For research use only
- Store solid at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in water (50 mg/mL)
Medchemexpress LLC Methyl 1-Cbz-azetidine-3-carboxylate | 757239-60-4 | MFCD11110708 | 99.6% | 249.26 g/mol | C13H15NO4 | 10 G
Methyl 1-Cbz-azetidine-3-carboxylate is a protected azetidine-derived building block used as a non-cleavable antibody-drug conjugate (ADC) linker and as an alkyl-chain PROTAC linker in medicinal chemistry and bioconjugation. The compound is supplied for research use only.
- High purity 99.6% (GC).
- Molecular weight 249.26 g/mol; chemical formula C13H15NO4.
- Suitable for ADC and PROTAC linker synthesis.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Provided for research use only; not for human use.
Medchemexpress LLC Methyl azetidine-3-carboxylate hydrochloride | 100202-39-9 | MFCD01861758 | 99.7% | 151.59 | C5H10ClNO2 | 1 G
Methyl azetidine-3-carboxylate hydrochloride is a methyl-substituted azetidine carboxylate hydrochloride salt supplied as a white to off-white solid for research use. It is used as a non-cleavable ADC linker and as an alkyl chain-based PROTAC linker in medicinal chemistry and conjugation applications.
- High purity (99.7%) suitable for synthesis and conjugation.
- Solid form, white to off-white, easy to handle and weigh.
- Storage: sealed at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Supplied in small research pack sizes (example: 1 G).
- Chemical identifiers: CAS 100202-39-9; formula C5H10ClNO2; molecular weight 151.59.
Medchemexpress LLC (R)-Azetidine-2-carboxylic acid | 7729-30-8 | MFCD00800731 | 99.6% | 101.10 g/mol | C4H7NO2 | 1 G
(R)-Azetidine-2-carboxylic acid is the R-enantiomer of azetidine-2-carboxylic acid, a nonproteinogenic amino acid used as an ADC linker and in biochemical research. The material is supplied as a solid for laboratory use.
- R-enantiomer of azetidine-2-carboxylic acid.
- Nonproteinogenic amino acid and ADC linker.
- Molecular formula C4H7NO2; molecular weight 101.10 g/mol.
- Purity reported as 99.6% (data sheet) and 99.9% (alternate listing).
- Appearance solid; store protected from light at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
- Available in small laboratory pack sizes for research use.
Medchemexpress LLC Azetidine-2-carboxylic acid | 2517-04-6 | 98.0% | C4H7NO2 | 1 G
Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline, found in common beets. It can be misincorporated into proteins in place of proline in many species, including humans, acting as a toxic and teratogenic agent. Studies show it incorporates into collagen synthesized by chick embryo cartilage in vitro.
- Appearance: Solid
- Color: White to off-white
- Structure classification: Amino acids
- Initial source: Plants (Beta vulgaris Linn.)
- Solubility: 50 mg/mL in water (requires ultrasonic)
- Solid storage: 4°C, sealed, away from moisture
- Solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC L-azetidine-2-carboxylic acid | 2133-34-8 | MFCD00005166 | 99.9% | 101.10 g/mol | C4H7NO2 | 1 G
L-azetidine-2-carboxylic acid is a non-proteinogenic amino acid and a proline analog used in biochemical and cell biology research to induce endoplasmic reticulum (ER) stress, protein misfolding, and related cellular pathways. It is provided as a solid for laboratory use and includes documentation such as COA and SDS.
- Non-proteinogenic amino acid proline analog.
- CAS number 2133-34-8.
- Molecular formula C4H7NO2.
- Molecular weight 101.10 g/mol.
- Purity 99.9%.
- Appearance solid, white to off-white.
- Soluble in water (100 mg/mL with ultrasonic assistance); sparingly soluble in DMSO.
- Storage 4°C, protect from light; in solution -80°C (6 months) or -20°C (1 month).
- Available pack sizes include 1 G.