Azobenzenes

Medchemexpress LLC Cadrofloxacin 25mg | 153808-85-6 | 25 MG

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Cadrofloxacin is an orally active fluoroquinolone antibiotic supplied for research use only. It exhibits activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria and is provided as a solid powder for laboratory research and assay development.

• Orally active fluoroquinolone antibacterial agent.
• Active against aerobic and anaerobic Gram-positive and Gram-negative bacteria.
• Supplied as a solid powder suitable for research use.
• Molecular formula C19H20F3N3O4; molecular weight 411.38 g·mol⁻¹.
• Typical purity approximately 98.2% as reported by the manufacturer.

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Medchemexpress LLC Valategrast | 220847-86-9 | MFCD18782681 | 98.6% | C30H32Cl3N3O4 | 10MG

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Valategrast (R-411 free base) is a potent, orally active dual antagonist of integrins α4β1 (VLA-4) and α4β7 provided for research use in inflammation and respiratory disease studies. It is supplied as a solid, characterized material for preclinical and in vitro investigations; not for human therapeutic use.

• Potent orally active dual integrin antagonist useful for mechanistic studies.
• Applicable to COPD and asthma research models.
• High purity solid suitable for analytical and biological assays.
• Available in multiple small pack sizes for research flexibility.
• Characterized with molecular weight, formula, and purity data for reproducibility.
• For research use only; not for human therapeutic use.

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Medchemexpress LLC N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 50 MG

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C-021 is a small-molecule antagonist of CC chemokine receptor 4 (CCR4) developed for research applications; it blocks CCR4-mediated signaling and functional chemotaxis, with low-nanomolar activity in binding and cell-based assays.

• Potent CCR4 antagonist with low-nanomolar binding activity.
• Prevents CCL22-derived [35S]GTPγS binding to CCR4 (IC50 18 nM) and inhibits functional chemotaxis (human 140 nM, mouse 39 nM).
• Molecular formula C27H41N5O2; molecular weight 467.65 g/mol.
• High purity (~99.95%).
• Solid form with recommended storage: powder -20°C (long term) or 4°C (short term); in solvent store at -80°C.
• Intended for research use only; not for human use.

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eMolecules​ Ambeed / 361114-Tetrabromodibenzo[ac]triphenylene / 100mg / 570572494 / A1363255 / / 2135768-85-1 / [null] / 643.998 / C26H12Br4

Ambeed / 361114-Tetrabromodibenzo[ac]triphenylene / 100mg / 570572494 / A1363255 / / 2135768-85-1 / [null] / 643.998 / C26H12Br4

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Medchemexpress LLC 4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1lambda6,2-benzothiazine-3-carboxamide | 34042-85-8 | MFCD00866053 | 95.0% | 337.37 g/mol | C13H11N3O4S2 | 5 MG

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Sudoxicam is a reversible, orally active cyclooxygenase (COX) antagonist from the enol-carboxamide class of non-steroidal anti-inflammatory drugs (NSAIDs). Provided for laboratory research use only, it exhibits anti-inflammatory, anti-edema, and antipyretic activities and is supplied as a characterized solid for use in in vitro and in vivo pharmacology studies.

• Reversible COX antagonist with anti-inflammatory, anti-edema, and antipyretic activity.
• Enol-carboxamide class NSAID commonly used in pharmacology research.
• Supplied as a solid suitable for dissolution in common laboratory solvents, such as DMSO.
• Characterized molecular weight and formula support reproducible experimental design.
• Available in small research quantities appropriate for dose-response and in vivo studies.
• Intended for research use only; not for human or clinical use.

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eMolecules​ 4'-Aminoazobenzene-4-sulphonic acid | 104-23-4 | MFCD00035778 | 1g

Combi-Blocks | 4'-Aminoazobenzene-4-sulphonic acid | 1g | 205402053 | QA-5157 | 97.000 | 104-23-4 | MFCD00035778 | 277.300 | C12H11N3O3S

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Medchemexpress LLC 2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amin | 877874-85-6 | MFCD22124522 | 99.8% | 459.45 | C20H16F3N7OS | 10 MG

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KG5 is an orally active small-molecule allosteric inhibitor that targets PDGFRβ and B-Raf, with additional inhibitory activity against Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic effects in cellular and animal models, including inhibition of MEK/ERK signaling and suppression of tumor growth and angiogenesis in vivo.

• Orally active allosteric inhibitor of PDGFRβ and B-Raf.
• Also inhibits Flt3, KIT, and c-Raf, broadening kinase coverage.
• Demonstrated anticancer and antiangiogenic activity in vitro and in vivo.
• Disrupts MEK/ERK phosphorylation and blocks S338 phosphorylation in endothelial cells.
• Potent cellular activity with EC50 values near 0.5-0.6 μM in vascular and endothelial cells.
• High purity suitable for research applications.
• Soluble in DMSO at high concentration and formulatable for in vivo dosing.
• Stable under recommended storage conditions to preserve activity.

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Medchemexpress LLC 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinol | 2248154-85-8 | MFCD32859311 | 99.4% | C26H30FN7O | 10MG

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KER047 (ALK2-IN-4) is a potent small-molecule inhibitor of activin receptor-like kinase-2 (ALK2) intended for research use in the study of ALK2-mediated signaling and metabolic disorders such as fibrodysplasia ossificans progressiva (FOP). The compound is provided in solid and solution formats for in vitro and preclinical investigations.

• Potent ALK2 inhibitor with demonstrated activity in research assays.
• Suitable for research into metabolic disease models, including FOP.
• High purity (99.4%) for reproducible experimental results.
• Available as solid powder and 10 mM solutions in DMSO for flexible dosing.
• Chemical formula C26H30FN7O and molecular weight 475.56 g/mol.
• Stable storage recommendations: powder at -20°C or 4°C; in solvent at -80°C or -20°C.

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eMolecules​ Medchem Express / Adezmapimod (hydrochloride) / 10mg / 446257795 / HY-10256A / / 869185-85-3 / MFCD01862622 / 413.900 / C21H17ClFN3OS

Medchem Express / Adezmapimod (hydrochloride) / 10mg / 446257795 / HY-10256A / / 869185-85-3 / MFCD01862622 / 413.900 / C21H17ClFN3OS

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eMolecules​ AstaTech / 44-BIS(BROMOMETHYL)BIPHENYL / 1g / 448278113 / T70531 / 95.000 / 20248-86-6 / MFCD00094419 / 340.058 / C14H12Br2

AstaTech / 44-BIS(BROMOMETHYL)BIPHENYL / 1g / 448278113 / T70531 / 95.000 / 20248-86-6 / MFCD00094419 / 340.058 / C14H12Br2

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eMolecules​ Ambeed / Nitromethylphenylsulfone / 250mg / 686660269 / A592579 / / 21272-85-5 / MFCD00015928 / 201.200 / C7H7NO4S

Ambeed / Nitromethylphenylsulfone / 250mg / 686660269 / A592579 / / 21272-85-5 / MFCD00015928 / 201.200 / C7H7NO4S

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eMolecules​ Medchem Express / FzM1.8 / 10mg / 533802341 / HY-117163 / / 2204290-85-5 / [null] / 322.320 / C18H14N2O4

Medchem Express / FzM1.8 / 10mg / 533802341 / HY-117163 / / 2204290-85-5 / [null] / 322.320 / C18H14N2O4

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Cayman Chemical Sulfasalazine 5g

A prodrug form of 5-aminosalicylic acid; inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells at 0.1-5 mM; inhibits cystine uptake through the system xc- cysteine-glutamate transporter at 0.25 mM and inhibits the growth of U-87MG glioma cells in an NF-κB independent manner at 0.25-1 mM; decreases diarrhea, increases food intake, and reverses body weight decreases in a mouse model of colitis at 100 mg/kg; suppresses antigen-induced arthritis in mice

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eMolecules​ Medchem Express / PS210 / 5mg / 600899855 / HY-121629 / / 1221962-86-2 / [null] / 380.319 / C19H15F3O5

Medchem Express / PS210 / 5mg / 600899855 / HY-121629 / / 1221962-86-2 / [null] / 380.319 / C19H15F3O5

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Medchemexpress LLC DB04760 | 544678-85-5 | 99.2% | 410.42 g·mol⁻¹ | C22H20F2N4O2 | 50MG

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DB04760 is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor (IC50 = 8 nM) used as a research reagent in preclinical studies. It has been reported to reduce paclitaxel-induced neurotoxicity and to exhibit anticancer activity. The compound has formula C22H20F2N4O2, molecular weight 410.42 g·mol⁻¹, and is supplied in solid and solution forms with high purity suitable for biological assays.

• Potent MMP-13 inhibition with IC50 = 8 nM.
• Non-zinc-chelating mechanism for selective target studies.
• Shown to reduce paclitaxel-induced neurotoxicity in models.
• Reported anticancer activity in preclinical research.
• Available as solid and as 10 mM solution in DMSO for assay flexibility.
• High purity (~99%) appropriate for biological testing.

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