Azolines
Medchemexpress LLC DSPE-thiol | 144735-82-0 | 90.0% | 836.19 g/mol | C44H86NO9PS | 10 MG
DSPE-thiol is a distearoylphosphatidylethanolamine lipid functionalized with a terminal thiol (-SH) group. It introduces reactive thiol chemistry to lipid assemblies, enabling covalent linkage to maleimide-containing molecules and the creation of phospholipid dimers for nanocarrier and membrane research.
- Provides reactive thiol functionality for selective conjugation with maleimide reagents.
- Facilitates liposome surface functionalization and targeted delivery studies.
- Enables synthesis of phospholipid dimers and cross-linked lipid structures.
- Integrates into lipid bilayers to impart stable, hydrophobic anchoring.
- Supplied in small research-scale quantities for laboratory use.
Medchemexpress LLC Thiol-PEG8-acid | 866889-02-3 | 97.0% | 250 MG
Thiol-PEG8-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC VH 101, thiol | 2358775-81-0 | 98.7% | C25H31FN4O4S2 | 100 MG
VH 101, thiol (compound 20) is a VHL ligand used for the synthesis of PROTACs.
- Acts as a VHL ligand for the synthesis of PROTACs.
- Appears as a solid.
- Soluble in DMSO (100 mg/mL).
- Applicable in cancer and cancer targeted therapy research.
- Part of the PROTAC ligands for E3 ligase category.
- Can be found in the ubiquitination compound library.
- Inhibits E3 ligase-recruiting moiety.
- Target for biological activity is VHL.
- Molecular weight is 534.67.
Medchemexpress LLC Hexa(ethylene glycol) dithiol | 89141-22-0 | 500 MG
Hexa(ethylene glycol) dithiol, also known as Thiol-PEG5-thiol (Bis-PEG5-thiol), is a bifunctional thiol cross-linker agent. It is intended for research and development applications, specifically targeting biochemical assay reagents. The chemical has a formula of C12H26O5S2 and a molecular weight of 314.46.
- Bifunctional thiol cross-linker agent
- Targets biochemical assay reagents
- Chemical formula: C12H26O5S2
- Molecular weight: 314.46
- Relative density: 1.113 g/cm³ at 25 °C
- Flash point: >110 °C
- Recommended storage at 2-8 °C
- Handle under nitrogen, protected from moisture
Medchemexpress LLC m-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | 250 MG
m-PEG-thiol (MW 2000) is a PEG-based PROTAC linker for the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrade target proteins