Azolines

Organic heterocyclic compounds that consist of a five-membered ring made up of four carbon atoms and one nitrogen atom, and only one carbon - carbon double bond.

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436

Medchemexpress LLC Thiol-PEG2-t-butyl ester | 1398044-50-2 | MFCD22574781 | 96.0% | C11H22O4S | 10MG

Thiol-PEG2-t-butyl ester is a short PEG-based linker bearing a tert-butyl-protected carboxylate and a thiol group (revealed after deprotection). It is intended for use in PROTAC synthesis and bioconjugation, providing a compact, flexible spacer with thiol reactivity for coupling to electrophiles or maleimides.

Short PEG spacer for flexible linker design.
Tert-butyl protection enables orthogonal deprotection strategies.
Terminal thiol functionality for efficient conjugation chemistry.
Suitable for PROTAC synthesis and general bioconjugation workflows.
Supplied in small research sizes for medicinal chemistry applications.

Pricing & Availability

437

Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 50 MG

M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein. PROTACs harness the intracellular ubiquitin-proteasome system for selective degradation of target proteins.