Benzimidazoles
Albendazole 98.0+%, TCI America™
CAS: 54965-21-8 Molecular Formula: C12H15N3O2S Molecular Weight (g/mol): 265.33 MDL Number: MFCD00083232 InChI Key: HXHWSAZORRCQMX-UHFFFAOYSA-N Synonym: albendazole,albenza,eskazole,valbazen,zentel,albendazol,proftril,albendazolum,bilutac,zental PubChem CID: 2082 ChEBI: CHEBI:16664 IUPAC Name: methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate SMILES: CCCSC1=CC=C2N=C(NC(=O)OC)NC2=C1
Oxibendazole 98.0+%, TCI America™
CAS: 20559-55-1 Molecular Formula: C12H15N3O3 Molecular Weight (g/mol): 249.27 MDL Number: MFCD00133728 InChI Key: RAOCRURYZCVHMG-UHFFFAOYSA-N Synonym: Methyl (5-Propoxy-1H-benzo[d]imidazol-2-yl)carbamate, (5-Propoxy-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester PubChem CID: 4622 IUPAC Name: methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate SMILES: CCCOC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
Cayman Chemical Omeprazole sulfon-d3 500ug
An internal standard for the quantification of omeprazole sulfone by GC- or LC-MS
Apexbio Technology LLC Fenbendazole 43210-67-9 500mg
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Medchemexpress LLC Omeprazole | 73590-58-6 | 100.0% | C17H19N3O3S | 500 MG
Omeprazole is a proton pump inhibitor (PPI) used to treat acid-related gastrointestinal disorders. It works by competitively inhibiting CYP2C19 activity. Additionally, Omeprazole inhibits the growth of Gram-positive and Gram-negative bacteria and is identified as a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor. This acid-labile compound is used in the treatment of various conditions including dyspepsia, peptic ulcer disease, and gastroesophageal reflux disease.
- Proton pump inhibitor
- Competitively inhibits CYP2C19 activity (Ki of 2 to 6 μM)
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Inhibits gastric acid secretion
- Used for treating acid-related gastrointestinal disorders
Selleck Chemical LLC Omeprazole Sodium
Omeprazole Sodium is the sodium salt form of omeprazole which is a proton pump inhibitor and suppresses gastric acid secretion Omeprazole Sodium is a metabolism-dependent inhibitor (MDI) of CYP2C19
Medchemexpress LLC Omeprazole sodium | 95510-70-6 | 99.1% | 100 MG
Omeprazole sodium is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM. It also inhibits the growth of Gram-positive and Gram-negative bacteria and acts as a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
- Used for acid-related gastrointestinal disorders
- Competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM
- Inhibits the growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)
- Used in the study of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome.
Cayman Chemical Omeprazole sulfon-d3 1mg
An internal standard for the quantification of omeprazole sulfone by GC- or LC-MS
Medchemexpress LLC Omeprazole | 73590-58-6 | 100.0% | 1 G
Omeprazole (H 16868) is a proton pump inhibitor (PPI) used in the treatment of acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole demonstrates inhibition of growth in both Gram-positive and Gram-negative bacteria and acts as a potent brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor and exosome inhibitor.
- Proton pump inhibitor (PPI)
- Used for treating acid-related gastrointestinal disorders
- Competitively inhibits CYP2C19 activity (Ki of 2 to 6 μM)
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Potent brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Acts as an exosome inhibitor
Apexbio Technology LLC Omeprazole 73590-58-6 10mM (in 1mL DMSO)
Omeprazole (73590-58-6) is a small-molecule inhibitor targeting H K -ATPase an enzyme essential for gastric acid secretion It is designed to inhibit the proton pump thereby reducing active transport of H ions into the gastric lumen Omeprazole exerts its biological activity primarily through irreversible binding to the H K -ATPase enzyme In in vitro studies Omeprazole demonstrates inhibitory activity with an IC value of approximately 5 8 M against purified H K -ATPase and an IC of 0 16 M in assays evaluating histamine-induced gastric acid production Based on these pharmacological properties Omeprazole holds research potential in the investigation of acid-mediated gastrointestinal conditions and related pathways
Apexbio Technology LLC Albendazole Oxide 54029-12-8 50mg
Albendazole Oxide (CAS 54029-12-8) is a small-molecule inhibitor targeting beta-tubulin It is designed to inhibit beta-tubulin polymerization in parasites thereby disrupting cytoplasmic microtubule structure and interfering with glucose metabolic pathways Albendazole Oxide exerts its biological activity primarily through inhibition of beta-tubulin polymerization In both in vitro and in vivo studies Albendazole Oxide demonstrates anti-parasitic activity with reported IC50 values typically ranging from nanomolar to micromolar concentrations depending on the parasite species and assay system Based on these pharmacological properties Albendazole Oxide holds research potential in the exploration of anti-parasitic pharmacodynamics notably for studies involving Echinococcus spp and other parasitic infections
Apexbio Technology LLC Omeprazole 73590-58-6 100mg
Omeprazole (73590-58-6) is a small-molecule inhibitor targeting H K -ATPase an enzyme essential for gastric acid secretion It is designed to inhibit the proton pump thereby reducing active transport of H ions into the gastric lumen Omeprazole exerts its biological activity primarily through irreversible binding to the H K -ATPase enzyme In in vitro studies Omeprazole demonstrates inhibitory activity with an IC value of approximately 5 8 M against purified H K -ATPase and an IC of 0 16 M in assays evaluating histamine-induced gastric acid production Based on these pharmacological properties Omeprazole holds research potential in the investigation of acid-mediated gastrointestinal conditions and related pathways
Cayman Chemical 4-hydroxy Omeprazole sulfide
A metabolite of omeprazole; has been found in wastewater effluent