Benzimidazoles
Albendazole 98.0+%, TCI America™
CAS: 54965-21-8 Molecular Formula: C12H15N3O2S Molecular Weight (g/mol): 265.33 MDL Number: MFCD00083232 InChI Key: HXHWSAZORRCQMX-UHFFFAOYSA-N Synonym: albendazole,albenza,eskazole,valbazen,zentel,albendazol,proftril,albendazolum,bilutac,zental PubChem CID: 2082 ChEBI: CHEBI:16664 IUPAC Name: methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate SMILES: CCCSC1=CC=C2N=C(NC(=O)OC)NC2=C1
Fenbendazole 98.0+%, TCI America™
CAS: 43210-67-9 Molecular Formula: C15H13N3O2S Molecular Weight (g/mol): 299.348 MDL Number: MFCD00144301 InChI Key: HDDSHPAODJUKPD-UHFFFAOYSA-N Synonym: Methyl [5-(Phenylthio)benzimidazol-2-yl]carbamate, [5-(Phenylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester PubChem CID: 3334 ChEBI: CHEBI:77092 IUPAC Name: methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)SC3=CC=CC=C3
Cayman Chemical Albendazole 25g
A benzimidazole anthelmintic; active against a variety of helminths, including liver flukes, tapeworms, and roundworms; eliminates Trichostrongylus in the fourth stomach of cattle and sheep (2.5-10 mg/kg) as well as other species; protects mice against lethal infection with A. suum larvae (0.05% in the diet); inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 µM), halts the cell cycle at the G2/M phase, and induces apoptosis; inhibits peritoneal tumor growth in an HT-29 mouse xenograft model (150 mg/kg, i.p.); inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50s = 6.9 and 0.21 µM, respectively)
Medchemexpress LLC Fenbendazole (Standard) | 43210-67-9 | 99.9% | 100 MG
Fenbendazole (Standard) is an analytical standard intended for research and analytical applications. It is an orally active benzimidazole anthelmintic agent with a broad antiparasitic range, primarily acting as a microtubule destabilizing agent.
- Binds to tubulin and disrupts microtubule equilibrium
- Stabilizes transcriptional activator HIF-1α
- Exhibits anti-proliferative activity, induces apoptosis, causes cell-cycle arrest, mitotic cell death, and has antitumor activity
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Apexbio Technology LLC Albendazole 54965-21-8 100mg
Albendazole (CAS 54965-21-8) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly thereby impairing cellular cytoskeletal function and parasite viability Albendazole exerts its biological activity primarily through binding to tubulin and inhibiting microtubule polymerization In tumor cell-based assays Albendazole demonstrates antiproliferative activity and induces cell cycle arrest autophagy and apoptosis with reported IC50 values typically ranging from 0 1 to 1 M depending on cell line and experimental conditions Based on these pharmacological properties Albendazole holds research potential in studies of parasitic infections microtubule dynamics tumor cell proliferation angiogenesis and programmed cell death
Medchemexpress LLC Albendazole sulfoxide-d3 | 1448346-38-0 | MFCD26142908 | 99.8% | 284.35 | C12H12D3N3O3S | 5 MG
Albendazole sulfoxide-d3 is a deuterium-labeled analogue of albendazole sulfoxide supplied for research use. It is intended as an isotope-labeled tracer or internal standard for quantitative analyses by NMR, GC-MS, and LC-MS.
- Deuterium-labeled internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, and LC-MS methods.
- High purity (99.79%).
- Molecular weight 284.35 and formula C12H12D3N3O3S.
- Available in small mg-scale packages, including 5 mg.
- Storage conditions for powder and solution provided for long-term stability.
Apexbio Technology LLC Fenbendazole 43210-67-9 10mM (in 1mL DMSO)
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Cayman Chemical Omeprazole sulfon-d3 1mg
An internal standard for the quantification of omeprazole sulfone by GC- or LC-MS
eMolecules 922730-98-1 | Medchem Express | Omeprazole sulfide-d3 | 1mg | 713706661 | HY-141776S | 332.44 | C17H19N3O2S
Medchem Express | Omeprazole sulfide-d3 | 1mg | 713706661 | HY-141776S | 922730-98-1 | 332.440 | C17H19N3O2S
Apexbio Technology LLC Fenbendazole 43210-67-9 500mg
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Apexbio Technology LLC Albendazole Oxide 54029-12-8 50mg
Albendazole Oxide (CAS 54029-12-8) is a small-molecule inhibitor targeting beta-tubulin It is designed to inhibit beta-tubulin polymerization in parasites thereby disrupting cytoplasmic microtubule structure and interfering with glucose metabolic pathways Albendazole Oxide exerts its biological activity primarily through inhibition of beta-tubulin polymerization In both in vitro and in vivo studies Albendazole Oxide demonstrates anti-parasitic activity with reported IC50 values typically ranging from nanomolar to micromolar concentrations depending on the parasite species and assay system Based on these pharmacological properties Albendazole Oxide holds research potential in the exploration of anti-parasitic pharmacodynamics notably for studies involving Echinococcus spp and other parasitic infections
Medchemexpress LLC Albendazole (Standard) (SKF-62979 (Standard)) | 54965-21-8 | 98.3% | 25 MG
Albendazole (Standard) is an analytical standard for research and analytical applications. This orally active, broad-spectrum parasiticide shows high effectiveness and low host toxicity, used for studying gastrointestinal parasites. It induces apoptosis and autophagy in cancer cells, inhibits tubulin polymerization, HIF-1α, and VEGF expression, and demonstrates antioxidant activity, inhibiting the glycolytic process in cancer cells.
- Analytical standard for research and analysis
- Orally active, broad-spectrum parasiticide
- High effectiveness and low host toxicity
- Used for research of gastrointestinal parasites
- Induces apoptosis and autophagy in cancer cells
- Inhibits tubulin polymerization, HIF-1α, and VEGF expression
- Exhibits antioxidant activity
- Inhibits glycolytic process in cancer cells
- Applied in HPLC, GC, and MS research experiments