Benzimidazoles
Albendazole 98.0+%, TCI America™
CAS: 54965-21-8 Molecular Formula: C12H15N3O2S Molecular Weight (g/mol): 265.33 MDL Number: MFCD00083232 InChI Key: HXHWSAZORRCQMX-UHFFFAOYSA-N Synonym: albendazole,albenza,eskazole,valbazen,zentel,albendazol,proftril,albendazolum,bilutac,zental PubChem CID: 2082 ChEBI: CHEBI:16664 IUPAC Name: methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate SMILES: CCCSC1=CC=C2N=C(NC(=O)OC)NC2=C1
Lansoprazole 98.0+%, TCI America™
CAS: 103577-45-3 Molecular Formula: C16H14F3N3O2S Molecular Weight (g/mol): 369.362 MDL Number: MFCD00866873 InChI Key: MJIHNNLFOKEZEW-UHFFFAOYSA-N Synonym: lansoprazole,prevacid,bamalite,monolitum,lansoprazol,agopton,limpidex,ogastro,lanzor,opiren PubChem CID: 3883 ChEBI: CHEBI:6375 IUPAC Name: 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
Cayman Chemical Omeprazole sulfIde 1g
An active metabolite of omeprazole; has been used as a precursor in the synthesis of esomeprazole; a potential impurity in commercial preparations of omeprazole
Sigma Aldrich Fine Chemicals Biosciences Omeprazole solid500MG
Omeprazole is a benzimidazole derivative a weak base and is lipophilic in nature. This compound is pH sensitive and does not exists in its original form at low pH.
Medchemexpress LLC (R)-omeprazole sodium | 161796-77-6 | 98.1% | C17H18N3NaO3S | 10MG
(R)-omeprazole sodium is the R-enantiomer of omeprazole supplied as the sodium salt. It is a gastric acid-resistant proton pump inhibitor used as a research reference standard to study gastric acid secretion and CYP2C19-mediated metabolism. The compound is provided with high chemical and enantiomeric purity for analytical and pharmacology studies.
- Molecular formula: C17H18N3NaO3S.
- Molecular weight: 367.4 g/mol.
- Purity: 98.1% (reported 98.07%).
- Enantiomeric excess: 99.84%.
- Function: reversible and metabolism-dependent inhibitor of CYP2C19.
- Intended use: reference standard and research compound for pharmacology and metabolism studies.
- Availability: includes small-scale 10 mg quantities suitable for analytical work.
Cayman Chemical 4-hydroxy Omeprazole sulfide
A metabolite of omeprazole; has been found in wastewater effluent
Apexbio Technology LLC Albendazole Oxide 54029-12-8 50mg
Albendazole Oxide (CAS 54029-12-8) is a small-molecule inhibitor targeting beta-tubulin It is designed to inhibit beta-tubulin polymerization in parasites thereby disrupting cytoplasmic microtubule structure and interfering with glucose metabolic pathways Albendazole Oxide exerts its biological activity primarily through inhibition of beta-tubulin polymerization In both in vitro and in vivo studies Albendazole Oxide demonstrates anti-parasitic activity with reported IC50 values typically ranging from nanomolar to micromolar concentrations depending on the parasite species and assay system Based on these pharmacological properties Albendazole Oxide holds research potential in the exploration of anti-parasitic pharmacodynamics notably for studies involving Echinococcus spp and other parasitic infections
Medchemexpress LLC Albendazole (Standard) | 54965-21-8 | 98.3% | 50 MG
Albendazole (Standard) is the analytical standard of Albendazole, intended for research and analytical applications. This orally active, broad-spectrum parasiticide is known for its high effectiveness and low host toxicity, and is utilized in the research of gastrointestinal parasites in both humans and animals.
- Induces apoptosis and autophagy in cancer cells.
- Inhibits tubulin polymerization.
- Inhibits HIF-1α and VEGF expression.
- Possesses antioxidant activity.
- Hinders the glycolytic process in cancer cells.
- Commonly used in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Serves as a reference standard for assays.
Medchemexpress LLC Fenbendazole (Standard) | 43210-67-9 | 99.9% | 100 MG
Fenbendazole (Standard) is an analytical standard intended for research and analytical applications. It is an orally active benzimidazole anthelmintic agent with a broad antiparasitic range, primarily acting as a microtubule destabilizing agent.
- Binds to tubulin and disrupts microtubule equilibrium
- Stabilizes transcriptional activator HIF-1α
- Exhibits anti-proliferative activity, induces apoptosis, causes cell-cycle arrest, mitotic cell death, and has antitumor activity
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Apexbio Technology LLC Albendazole 54965-21-8 10mM (in 1mL DMSO)
Albendazole (CAS 54965-21-8) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly thereby impairing cellular cytoskeletal function and parasite viability Albendazole exerts its biological activity primarily through binding to tubulin and inhibiting microtubule polymerization In tumor cell-based assays Albendazole demonstrates antiproliferative activity and induces cell cycle arrest autophagy and apoptosis with reported IC50 values typically ranging from 0 1 to 1 M depending on cell line and experimental conditions Based on these pharmacological properties Albendazole holds research potential in studies of parasitic infections microtubule dynamics tumor cell proliferation angiogenesis and programmed cell death