Benzimidazoles
Apexbio Technology LLC Fenbendazole 43210-67-9 10mM (in 1mL DMSO)
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Medchemexpress LLC Omeprazole sodium | 95510-70-6 | 99.1% | 100 MG
Omeprazole sodium is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM. It also inhibits the growth of Gram-positive and Gram-negative bacteria and acts as a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
- Used for acid-related gastrointestinal disorders
- Competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM
- Inhibits the growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)
- Used in the study of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome.
Cayman Chemical Omeprazole sulfon-d3 1mg
An internal standard for the quantification of omeprazole sulfone by GC- or LC-MS
Medchemexpress LLC Omeprazole | 73590-58-6 | 99.9% | 345.42 g/mol | C17H19N3O3S | 10 MG
Omeprazole (Standard) is an analytical reference standard of omeprazole supplied as a purified solid for research and analytical applications. It is intended for use in assay calibration, method development, and quality control, and is documented with a certificate of analysis.
- High reported purity (99.9%).
- Chemical formula C17H19N3O3S and molecular weight 345.42 g/mol.
- Provided as a 10 MG pack for analytical use.
- Suitable for assay calibration and method development.
- Characterized by a downloadable datasheet and COA.
Medchemexpress LLC N-(4-methoxy-2-nitrophenyl)acetamide | 119-81-3 | MFCD00017018 | 10g
Omeprazole impurity 1 is an impurity ofOmeprazole (HY-B0113)
![Medchemexpress LLC 2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-6-methoxy-1H-benzimidazole | 220757-74-4 | MFCD09840353 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000267119.png-250.jpg)
Medchemexpress LLC 2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-6-methoxy-1H-benzimidazole | 220757-74-4 | MFCD09840353 | 100mg
Omeprazole impurity 13 is an impurity ofOmeprazole (HY-B0113)
Apexbio Technology LLC Omeprazole 73590-58-6 10mM (in 1mL DMSO)
Omeprazole (73590-58-6) is a small-molecule inhibitor targeting H K -ATPase an enzyme essential for gastric acid secretion It is designed to inhibit the proton pump thereby reducing active transport of H ions into the gastric lumen Omeprazole exerts its biological activity primarily through irreversible binding to the H K -ATPase enzyme In in vitro studies Omeprazole demonstrates inhibitory activity with an IC value of approximately 5 8 M against purified H K -ATPase and an IC of 0 16 M in assays evaluating histamine-induced gastric acid production Based on these pharmacological properties Omeprazole holds research potential in the investigation of acid-mediated gastrointestinal conditions and related pathways
Medchemexpress LLC 5-Hydroxy Omeprazole-d3 | 2748479-83-4 | 98.3% | 1 MG
5-Hydroxy Omeprazole-d3 is a deuterium labeled version of 5-Hydroxyomeprazole. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs
Cayman Chemical Albendazole sulfon-d3 25mg
An internal standard for the quantification of albendazole sulfone by GC- or LC-MS
Cayman Chemical Albendazole sulfon 10mg
An active metabolite of albendazole; inhibits spore formation of E. hellem, E. cuniculi, and E. intestinalis in vitro (IC90s = <0.0001, <0.001, and <0.1 UG/ml, respectively)
Selleck Chemical LLC Albendazole S1640-1g
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations
Cayman Chemical Albendazole 50g
A benzimidazole anthelmintic; active against a variety of helminths, including liver flukes, tapeworms, and roundworms; eliminates Trichostrongylus in the fourth stomach of cattle and sheep (2.5-10 mg/kg) as well as other species; protects mice against lethal infection with A. suum larvae (0.05% in the diet); inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 µM), halts the cell cycle at the G2/M phase, and induces apoptosis; inhibits peritoneal tumor growth in an HT-29 mouse xenograft model (150 mg/kg, i.p.); inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50s = 6.9 and 0.21 µM, respectively)
Apexbio Technology LLC Fenbendazole 43210-67-9 500mg
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Medchemexpress LLC Albendazole sulfoxide-d3 | 1448346-38-0 | MFCD26142908 | 99.8% | 284.35 | C12H12D3N3O3S | 5 MG
Albendazole sulfoxide-d3 is a deuterium-labeled analogue of albendazole sulfoxide supplied for research use. It is intended as an isotope-labeled tracer or internal standard for quantitative analyses by NMR, GC-MS, and LC-MS.
- Deuterium-labeled internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, and LC-MS methods.
- High purity (99.79%).
- Molecular weight 284.35 and formula C12H12D3N3O3S.
- Available in small mg-scale packages, including 5 mg.
- Storage conditions for powder and solution provided for long-term stability.