Benzimidazoles
Cayman Chemical Albendazole 10g
An inactive metabolite of TXA2 serum levels positively correlate with platelet COX-1 activation urinary levels reflect intrarenal TXA2 synthesis
Cayman Chemical Omeprazole sulfIde 1g
A colorimetric substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4
Cayman Chemical Omeprazole sulfIde 500mg
A c-Met inhibitor (Ki 4 8 nM) 1000-fold selective for c-Met over a panel of 150 kinases inhibits the proliferation of and induces apoptosis in GTL-16 cells (IC50s 12 and 31 nM respectively) inhibits HGF-induced migration of H441 cells (IC50 11 nM) reduces tumor growth in a GTL-16 mouse xenograft model at 1-30 mg/kg
Cayman Chemical Albendazole sulfon-d3 25mg
An antiviral nucleoside analog inhibits HIV replication in infected human PBMCs (EC50 0 17 UM) reduces viral plaque formation in HSV-1-infected CV-1 cells at 1 3 10 or 30 UM
Cayman Chemical 4-hydroxy Omeprazole sulfide
An alkaloid and a toxin reduces sciatic nerve stimulation-induced CMAPS in isolated lizard extensor digitorum longus muscle (IC50 156 UM) induces neuromuscular impairment in mice at 85 mg/kg induces lethality in mice (LD50 113 mg/kg)
Cayman Chemical Omeprazole sulfon-d3 500ug
An antiviral guanosine analog has activity against multiple laboratory and clinical isolate strains of HSV-1 HSV-2 and VZV in a plaque reduction assay (IC50s 0.4-3.1 g/ml) inhibits HSV-1 and HSV-2 replication (IC99s 0.4 and 0.7 g/ml respectively) and DNA synthesis (IC50 0.04 g/ml) in MRC-5 cells reduces the severity of skin lesions caused by HSV-1 in guinea pigs and mice prevents development of HSV-2-induced genital lesions in guinea pigs infected intravaginally
Selleck Chemical LLC Albendazole S1640-1g
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations
Selleck Chemical LLC Omeprazole S1389-1g
Omeprazole is a proton pump inhibitor that blocks H( )-K( )-ATPase used to treat dyspepsia peptic ulcer disease gastroesophageal reflux disease laryngopharyngeal reflux and Zollinger Ellison syndrome
Selleck Chemical LLC Omeprazole Sodium
Omeprazole Sodium is the sodium salt form of omeprazole which is a proton pump inhibitor and suppresses gastric acid secretion Omeprazole Sodium is a metabolism-dependent inhibitor (MDI) of CYP2C19
Cayman Chemical Albendazole sulfon 25mg
A GPR52 antagonist (IC50 0 63 UM) reduces mHTT protein levels in STHdhQ7/Q111 cells in a concentration-dependent manner reduces apoptosis induced by growth factor deprivation in primary striatal neurons isolated from HdhQ7/Q140 mice decreases striatal levels of soluble and insoluble mHTT as well as increases the latency to fall in the rotarod test in the HdhQ140 mouse model of Huntingtons disease at 5 mg/kg
Cayman Chemical Albendazole sulfon-d3 5mg
A carbenapenem antibiotic active against a panel of clinical isolates from a variety of bacterial species (MIC50s 0 0039-8 Ug/ml) inhibitsBlactamase decreases the number of CFUs in the lungs in a mouse model of penicillin-resistant S pneumoniae infection at doses ranging from 0 32 to 3 2 mg/kg
Cayman Chemical Albendazole sulfon 10mg
A GPR52 antagonist (IC50 0 63 UM) reduces mHTT protein levels in STHdhQ7/Q111 cells in a concentration-dependent manner reduces apoptosis induced by growth factor deprivation in primary striatal neurons isolated from HdhQ7/Q140 mice decreases striatal levels of soluble and insoluble mHTT as well as increases the latency to fall in the rotarod test in the HdhQ140 mouse model of Huntingtons disease at 5 mg/kg
Cayman Chemical Omeprazole N-oxIde 10mg
A deoxyribonucleotide oral administration in combination with dTMP increases lifespan in a Tk2 H126N knock-in mouse model of TK2 deficiency