Benzimidazoles
Selleck Chemical LLC Albendazole S1640-1g
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations
Apexbio Technology LLC Albendazole 54965-21-8 10mM (in 1mL DMSO)
Albendazole (CAS 54965-21-8) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly thereby impairing cellular cytoskeletal function and parasite viability Albendazole exerts its biological activity primarily through binding to tubulin and inhibiting microtubule polymerization In tumor cell-based assays Albendazole demonstrates antiproliferative activity and induces cell cycle arrest autophagy and apoptosis with reported IC50 values typically ranging from 0 1 to 1 M depending on cell line and experimental conditions Based on these pharmacological properties Albendazole holds research potential in studies of parasitic infections microtubule dynamics tumor cell proliferation angiogenesis and programmed cell death
Medchemexpress LLC Albendazole (Standard) | 54965-21-8 | 98.3% | 50 MG
Albendazole (Standard) is the analytical standard of Albendazole, intended for research and analytical applications. This orally active, broad-spectrum parasiticide is known for its high effectiveness and low host toxicity, and is utilized in the research of gastrointestinal parasites in both humans and animals.
- Induces apoptosis and autophagy in cancer cells.
- Inhibits tubulin polymerization.
- Inhibits HIF-1α and VEGF expression.
- Possesses antioxidant activity.
- Hinders the glycolytic process in cancer cells.
- Commonly used in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Serves as a reference standard for assays.
Medchemexpress LLC Fenbendazole (Standard) | 43210-67-9 | 99.9% | 100 MG
Fenbendazole (Standard) is an analytical standard intended for research and analytical applications. It is an orally active benzimidazole anthelmintic agent with a broad antiparasitic range, primarily acting as a microtubule destabilizing agent.
- Binds to tubulin and disrupts microtubule equilibrium
- Stabilizes transcriptional activator HIF-1α
- Exhibits anti-proliferative activity, induces apoptosis, causes cell-cycle arrest, mitotic cell death, and has antitumor activity
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Apexbio Technology LLC Fenbendazole 43210-67-9 10mM (in 1mL DMSO)
Fenbendazole (CAS 43210-67-9) is a small-molecule inhibitor targeting microtubule polymerization It is designed to bind tubulin and disrupt microtubule dynamics thereby impairing cytoskeletal integrity and protein homeostasis Fenbendazole exerts its biological activity primarily through microtubule destabilization and disruption of proteasomal function triggering the unfolded protein response (UPR) pathway In various cancer cell lines fenbendazole demonstrates cytotoxic and anti-proliferative activity with reported IC50 values generally ranging from approximately 0 5 to 5 M Based on these pharmacological properties fenbendazole holds research potential in antiparasitic therapy and cancer drug repurposing studies
Medchemexpress LLC Omeprazole | 73590-58-6 | 99.9% | 345.42 | 100 MG
Omeprazole is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity and inhibits the growth of both Gram-positive and Gram-negative bacteria. Additionally, it is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor and an exosome inhibitor.
- Proton pump inhibitor (PPI)
- Competitively inhibits CYP2C19 activity
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Exosome inhibitor
- Inhibits gastric acid secretion
- Acid-labile compound
Medchemexpress LLC Omeprazole-d3 | 922731-01-9 | 98.99% | C17H16D3N3O3S | 10 MM/1 ML
Omeprazole-d3 is a deuterium labeled form of Omeprazole, a proton pump inhibitor (PPI) used for acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity (Ki of 2 to 6 μM) and also inhibits the growth of Gram-positive and Gram-negative bacteria. This compound can be used as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled compound
- Acts as a proton pump inhibitor
- Inhibits CYP2C19 activity
- Inhibits growth of Gram-positive and Gram-negative bacteria
- Suitable as a tracer for quantitative analysis
- Functions as an internal standard for quantitative analysis
Medchemexpress LLC Omeprazole | 73590-58-6 | 100.0% | C17H19N3O3S | 1 ML
Omeprazole is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity and inhibits the growth of Gram-positive and Gram-negative bacteria. Additionally, it is a potent brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor, functioning as an exosome inhibitor.
- Proton pump inhibitor (PPI)
- Used for treating acid-related gastrointestinal disorders
- Competitively inhibits CYP2C19 activity
- Inhibits the growth of Gram-positive and Gram-negative bacteria
- Potent brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor
- Functions as an exosome inhibitor
- Intended for research use only
Medchemexpress LLC Omeprazole sodium | 95510-70-6 | 99.1% | 100 MG
Omeprazole sodium is a proton pump inhibitor (PPI) used for treating acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM. It also inhibits the growth of Gram-positive and Gram-negative bacteria and acts as a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
- Used for acid-related gastrointestinal disorders
- Competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM
- Inhibits the growth of Gram-positive and Gram-negative bacteria
- Potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)
- Used in the study of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome.
Sigma Aldrich Fine Chemicals Biosciences Omeprazole solid500MG
Omeprazole is a benzimidazole derivative a weak base and is lipophilic in nature. This compound is pH sensitive and does not exists in its original form at low pH.
Cayman Chemical Omeprazole sulfon-d3 1mg
An internal standard for the quantification of omeprazole sulfone by GC- or LC-MS
Medchemexpress LLC Omeprazole-d3 | 922731-01-9 | 99.0% | C17H16D3N3O3S | 1 MG
Omeprazole-d3 (H 16868-d3) is a deuterium-labeled version of Omeprazole. Omeprazole is a proton pump inhibitor (PPI) used in the treatment of acid-related gastrointestinal disorders, competitively inhibiting CYP2C19 activity and the growth of both Gram-positive and Gram-negative bacteria. The incorporation of stable heavy isotopes into drug molecules, such as deuterium, can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Suitable for treatment of acid-related gastrointestinal disorders
- Inhibits growth of Gram-positive and Gram-negative bacteria
Sigma Aldrich Fine Chemicals Biosciences Pantoprazole sodium hydrate >=98% (HPLC) | 718635-09-7 | 50MG
Pantoprazole sodium hydrate >=98% (HPLC) | Purity: >=98% (HPLC) | 718635-09-7 | 50MG