Benzodiazepines
Medchemexpress LLC FAUC 365 10mg | 474432-66-1 | 462.44 g/mol | C23H25Cl2N3OS | 10 MG
FAUC 365 is a small-molecule dopamine D3 receptor-selective antagonist used in neuropharmacology research. It shows high affinity for the D3 receptor (Ki ≈ 0.5 nM) and is supplied as a high-purity powder for in vitro and in vivo studies.
- High affinity for dopamine D3 receptor (Ki ≈ 0.5 nM).
- Demonstrates selectivity over D2 and D4 receptor subtypes.
- High purity suitable for research applications (purity reported ~98.75%).
- Available in small pack sizes, including 10 mg.
- Soluble in DMSO; in vivo formulation protocols provided.
- Store powder at recommended temperatures to maintain stability.
eMolecules Pharmablock / 7-chloro-2345-tetrahydro-1H-1-benzazepin-5-one / 25mg / 784549693 / SYN0084 / 0.000 / 160129-45-3 / MFCD06738694 / 195.650 / C10H10ClNO
Pharmablock / 7-chloro-2345-tetrahydro-1H-1-benzazepin-5-one / 25mg / 784549693 / SYN0084 / 0.000 / 160129-45-3 / MFCD06738694 / 195.650 / C10H10ClNO
![eMolecules AstaTech / ETHYL 1-OXO-2345-TETRAHYDRO-1H-PYRROLO[12-A][14]DIAZEPINE-8-CARBOXYLATE / 0.25g / 296372201 / 50461 / 95.000 / 1338563-17-9 / MFCD22543877 / 222.244 / C11H14N2O3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477545.JPG-250.jpg)
eMolecules AstaTech / ETHYL 1-OXO-2345-TETRAHYDRO-1H-PYRROLO[12-A][14]DIAZEPINE-8-CARBOXYLATE / 0.25g / 296372201 / 50461 / 95.000 / 1338563-17-9 / MFCD22543877 / 222.244 / C11H14N2O3
AstaTech / ETHYL 1-OXO-2345-TETRAHYDRO-1H-PYRROLO[12-A][14]DIAZEPINE-8-CARBOXYLATE / 0.25g / 296372201 / 50461 / 95.000 / 1338563-17-9 / MFCD22543877 / 222.244 / C11H14N2O3
Medchemexpress LLC Clozapine | 5786-21-0 | MFCD00153785 | C18H19ClN4 | 10MG
Clozapine reference standard (CAS 5786-21-0) provided as a certified solid for laboratory research and analytical use. Intended for method development, calibration, and quality control, this material is formulated to support accurate identity confirmation and quantitative assays in HPLC, LC-MS, and related analytical workflows.
- Intended for research and analytical applications.
- Suitable as a reference standard for method development and calibration.
- Supplied as a solid powder in small, certified pack sizes.
- Compatible with HPLC and LC-MS workflows.
- Provides traceable identity linked to CAS 5786-21-0.
Selleck Chemical LLC Clozapine S2459-50mg
Clozapine (HF 1854 LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist used in the treatment of schizophrenia
Apexbio Technology LLC Coelenterazine 55779-48-1 5mg
Coelenterazine (CAS 55779-48-1) is a small molecule substrate for bioluminescent enzymes that generates a chemiluminescent signal upon oxidation by reactive oxygen species (ROS) particularly superoxide anions and peroxynitrite In rat hepatocytes it exhibits an IC50 of approximately 69 M toward superoxide anions Coelenterazine demonstrates concentration-dependent antioxidant activity enhancing cell viability and decreasing lipid peroxidation under oxidative stress induced by tert-butyl hydroperoxide It is widely applied in biomedical research including ELISA bioluminescence resonance energy transfer (BRET) high-throughput screening (HTS) and in vivo imaging studies of ROS in cancer models
Medchemexpress LLC FAUC 365 25mg | 474432-66-1 | 25 MG
FAUC 365 is a selective dopamine D3 receptor antagonist used as a research reagent to probe D3-mediated signaling in neuropharmacology and CNS disease models.
- Highly selective dopamine D3 receptor antagonist (Ki = 0.5 nM).
- Lower potency at related receptors (D4.4 Ki ≈ 340 nM; D2short Ki ≈ 2,600 nM; D2Long Ki ≈ 3,600 nM).
- Chemical formula C23H25Cl2N3OS; molecular weight 462.44 g/mol.
- Purity ~98.8% as supplied.
- Appearance: off-white to light yellow solid.
- Storage: powder -20°C for long-term storage; 4°C for shorter term.
- Supplied as 25 mg research quantity.
Selleck Chemical LLC Coelenterazine
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
Selleck Chemical LLC Coelenterazine
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
Apexbio Technology LLC Clozapine 5786-21-0 10mM (in 1mL DMSO)
Clozapine (CAS 5786-21-0) is an atypical antipsychotic agent extensively studied for treating schizophrenia refractory to standard antipsychotics Clozapine exhibits high affinity binding to serotonin receptors 5-HT1c and 5-HT2 with reported pKi values of 8 07 and 7 63 respectively Additionally clozapine interacts with multiple dopamine receptor subtypes (D1-D5) displaying Ki values of 141 nM (D1) 80 nM (D2) 230 nM (D3) 89 nM (D4) and 250 nM (D5) Due to its distinctive receptor affinity profile clozapine serves as an important pharmacological tool in research on serotonin- and dopamine-mediated signaling mechanisms in psychiatric disorders