Benzodiazepines
Clozapine N-oxide, 99%, Thermo Scientific Chemicals
CAS: 34233-69-7 Molecular Formula: C18H19ClN4O Molecular Weight (g/mol): 342.827 MDL Number: MFCD00210190 InChI Key: WYRDWWAASBTJLM-UHFFFAOYSA-N Synonym: clozapine n-oxide,clozapine-n-oxide,unii-mza8bk588j,chembl1688,mza8bk588j,n-oxyclozapine,clozapine n-oxide cno,oguczbiqsyywef-uhfffaoysa-n PubChem CID: 2819 IUPAC Name: 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine SMILES: C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]
Clozapine, 97%
CAS: 5786-21-0 Molecular Formula: C18H19ClN4 Molecular Weight (g/mol): 326.828 MDL Number: MFCD00153785 InChI Key: ZUXABONWMNSFBN-UHFFFAOYSA-N Synonym: clozapine,leponex,clozapin,clozaril,fazaclo,clorazil,iprox,clozapinum,asaleptin,clozapina PubChem CID: 2818 IUPAC Name: 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine SMILES: CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
Pirenzepine dihydrochloride, 99%
CAS: 29868-97-1 Molecular Formula: C19H23Cl2N5O2 Molecular Weight (g/mol): 424.326 MDL Number: MFCD00055214 InChI Key: FFNMBRCFFADNAO-UHFFFAOYSA-N Synonym: pirenzepine dihydrochloride,pirenzepine hydrochloride,tabe,bisvanil,leblon,maghen,pirenzepine hcl,pirenzepine 2hcl,ls 519 dihydrochloride,unii-10ym403fls PubChem CID: 71405 ChEBI: CHEBI:32014 IUPAC Name: 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;dihydrochloride SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl
2,3,4,5-Tetrahydro-1H-1,4-benzodiazepine, 95%
CAS: 5946-39-4 Molecular Formula: C9H12N2 Molecular Weight (g/mol): 148.209 MDL Number: MFCD03789577 InChI Key: MLXBHOCKBUILHN-UHFFFAOYSA-N Synonym: 2,3,4,5-tetrahydro-1h-benzo e 1,4 diazepine,1h-1,4-benzodiazepine, 2,3,4,5-tetrahydro,2,3,4,5-tetrahydro-1h benzo e 1,4 diazepine,pubchem14772,acmc-1anok,d0v0nj,tetrahydrobenzo 1,4 diazepine,2,3,4,5-tetrahydro-1h-1,4-benzodiazepine,2,3,4,5-tetrahydro-1h-benzo 1,4 diazepine PubChem CID: 2771762 IUPAC Name: 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine SMILES: C1CNC2=CC=CC=C2CN1
Clozapine
CAS: 5786-21-0 Molecular Formula: C18H19ClN4 Molecular Weight (g/mol): 326.83 InChI Key: ZUXABONWMNSFBN-UHFFFAOYSA-N IUPAC Name: 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0³,⁸]pentadeca-1,3,5,7,10,12,14-heptaene SMILES: CN1CCN(CC1)C1=C2C=CC=CC2=NC2=CC=C(Cl)C=C2N1
Sigma Aldrich Fine Chemicals Biosciences Clozapine | 5786-21-0 | MFCD00153785 | 25MG
Clozapine | Mol Wt: 326.82 | 5786-21-0 | MFCD00153785 | 25MG
Cayman Chemical Coelenterazine 400a hydrochl
A bisdeoxy derivative of coelenterazine that produces an emission maximum of 395 nm following conversion by Renilla luciferase; commonly used in BRET2 protocols to evaluate protein-protein interactions
Medchemexpress LLC FAUC 365 100mg | 474432-66-1 | 462.44 g·mol⁻¹ | C23H25Cl2N3OS | 100 MG
FAUC 365 is a research chemical described as a dopamine D3 receptor-selective antagonist used for in vitro pharmacology and receptor-binding studies. It is supplied in solid form and as a DMSO solution for biochemical assays.
- Dopamine D3 receptor-selective antagonist.
- High potency with reported Ki ≈ 0.5 nM at D3.
- Purity 98.8%.
- Chemical formula C23H25Cl2N3OS; molecular weight 462.44 g·mol⁻¹.
- Available in small pack sizes, including 100 mg, and solution formats.
- For research use only; not for human or clinical use.
TARGETMOL CHEMICALS INC Clozapine N-oxide dihydrochlor
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Clozapine N-oxide dihydrochloride, a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs), crosses the blood-brain barrier and activates DREADD receptors hM3Dq and hM4Di. Purity 98.11%
Selleck Chemical LLC Clozapine S2459-1g
Clozapine (HF 1854 LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist used in the treatment of schizophrenia
TARGETMOL CHEMICALS INC Coelenteramine 400a 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Coelenteramine 400a (Coelenterazine 400a), a Coelenterazine derivative, serves as a substrate for Renilla luciferase (RLuc), facilitating the emission of blue light at 395 nm [1] [2]. This compound alters the bioluminescence color of RLuc by substituting the sulfur and oxygen heteroatoms in the methylene bridge. Coelenteramine 400a enhances signal resolution, proving useful in bioluminescence resonance energy transfer (BRET) research [3]. Purity 98.15%
Selleck Chemical LLC Coelenterazine
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
TARGETMOL CHEMICALS INC Clozapine 200MG
Also available in 1 g, 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Purity 99.93%
TARGETMOL CHEMICALS INC CLOZAPINE N-OXIDE 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4 whose activities in turn can be affected by drugs and disease [2]. Clozapine N-oxide is normally biologically inactive. However it can be used in designer receptor exclusively activated by designer drugs also known as DREADDs technology to modulate synthetic receptors in vivo [3]. purity: 99%
- 1
- 2