Benzoxadiazoles
Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2508.5 g/mol | C106H178N6O55Na4 | 1mg
Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]
Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2,528.55 g/mol | C106H182N6O56·4Na | 100ug
Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]
Medchemexpress LLC 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG
Medchemexpress LLC NBD-556 | 333353-44-9 | 99.6% | 337.84 g·mol-1 | C17H24ClN3O2 | 10 MG
NBD-556 is a small-molecule CD4 mimetic that inhibits HIV-1 entry by blocking the gp120-CD4 interaction. It is supplied as a solid research compound for use in biochemical and cell-based assays investigating viral entry and fusion.
- CD4 mimetic that blocks the gp120-CD4 interaction.
- Inhibits HIV-1 entry and fusion in cell-based assays.
- High purity (99.6%).
- Molecular weight 337.84 g·mol-1.
- CAS number 333353-44-9.
- Soluble in DMSO (≈33.33 mg/mL); ultrasonic treatment may be required.
- Supplied as a 10 mg solid; store powder at -20°C for long-term storage.
Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | 100 MG
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist. It binds to HIV-1 gp120 and shows potent antiviral activity.
- Potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses.
- Binds to HIV-1 gp120.
- Low cytotoxicity (CC50>100 μM).
- Anti-HIV-1 activity (IC50=0.16 μM) and Cytotoxicity (CC50=109.3 μM) in single-cycle (TZM-bl Cells) assay.
- Does not induce toxicity in the U87-CD4-CXCR4 cell line at doses used for assay.
Medchemexpress LLC NBD-F (4-Fluoro-7-nitrobenzofurazan) | 29270-56-2 | 98.87% | 1 ML
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent developed for amino acid analysis. It reacts with primary or secondary amines to create a fluorescent product, which is used for the analysis of amino acids and low molecular weight amines. NBD-F is also applied in the analysis of other amino acid derivatives like N-methyl-D-aspartic acid and glutathione. This reagent offers a simple derivatization procedure and its derivatives are highly stable.
- Pro-fluorescent reagent developed for amino acid analysis.
- Reacts with primary or secondary amines to produce a fluorescent product.
- Used for analysis of amino acids and low molecular weight amines, and other amino acid derivatives.
- Simple derivatization procedure, and derivatives are highly stable.
- Appearance: solid.
- Color: light yellow to yellow.
- Emission (Em): 515.
- Excitation (Ex): 445.
Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid ammonium | 84806-27-9 | 98.96% | 50 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label that can be utilized for detecting dissolved thiol-disulfide, such as Cys and GSH. It is intended for research use only and not for patient use.
- Fluorescent label: can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH).
- Purity: 98.96%.
- Appearance: solid.
- Color: light yellow to yellow.
- Emission (Em): 495.
- Excitation (Ex): 478.
- Solubility: soluble in DMSO (250 mg/mL) and H2O (≥ 50 mg/mL).
- Storage: 4°C, sealed storage, away from moisture and light. In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light).
Medchemexpress LLC 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.75% | 50 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.75% | 50 MG
Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid (ammonium) | 84806-27-9 | 99.0% | 25 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label primarily used for detecting dissolved thiol-disulfide compounds such as Cys and GSH. It is suitable for various laboratory applications requiring fluorescence-based detection.
- Fluorescent label for thiol-disulfide detection
- Used with Cys and GSH
- Research use only
- Excitation wavelength range: 451-495 nm Blue
- Emission wavelength range: 451-495 nm Blue
Medchemexpress LLC 7-fluorobenzofurazan-4-sulfonic acid ammonium | 84806-27-9 | 99.0% | 235.19 | C6H6FN3O4S | 10 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent labeling reagent (ammonium salt) used for derivatization and sensitive detection of thiol-containing compounds in analytical assays.
- Fluorescent reagent for detecting thiol-disulfide species such as cysteine and glutathione.
- High reported purity (~98.9%), suitable for analytical use.
- Available in small research-scale quantities for laboratory experiments.
- Compatible with pre-column derivatization and HPLC fluorescence detection methods.
- For research use only; not intended for human use.
Medchemexpress LLC C6 NBD glucosylceramide | 94885-03-7 | MFCD00870345 | 98.0% | 737.88 g/mol | C36H59N5O11 | 500 UG
C6 NBD glucosylceramide is a fluorescently labeled short-chain glucosylceramide used as a probe to study sphingolipid metabolism, intracellular trafficking, and glucosylceramide synthase activity. It is provided as a yellow-orange solid for research use and exhibits strong NBD fluorescence for sensitive detection in biochemical and cell-based assays.
- Fluorescent probe with excitation 466 nm and emission 535 nm.
- High purity suitable for biochemical assays.
- Short-chain analog for efficient cellular uptake.
- Stable solid; store protected from moisture and light.
- Compact 500 μg format for small-scale experiments.
Medchemexpress LLC NBD-X acid | 88235-25-0 | 99.2% | 25 MG
NBD-X acid is a fluorescent probe that contains a nitrobenzoxadiazole group and can be utilized to investigate the structure and function of biomolecules.
- Fluorescent probe.
- Contains a nitrobenzoxadiazole group.
- Can be used to study the structure and function of biomolecules.
Medchemexpress LLC NBD-14270 | 2411819-82-2 | 99.53% | 425.43 | 1 ML
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. It binds to HIV-1 gp120 and demonstrates potent antiviral activity, with low cytotoxicity (CC50>100 μM).
- Potent HIV-1 entry antagonist
- IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses
- Binds to HIV-1 gp120
- Demonstrates potent antiviral activity
- Low cytotoxicity (CC50>100 μM)
Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | 428.40 | 50 MG
NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. It binds to HIV-1 gp120 and demonstrates potent antiviral activity (EC50 < 200 nM). It is active against HIV-1 in single-cycle (TZM-bl cells) and multi-cycle (MT-2 cells) assays.
- Potent HIV-1 entry antagonist with an IC50 of 89 nM
- Binds to HIV-1 gp120
- Demonstrates potent antiviral activity (EC50 < 200 nM)
- Prevents HIV-1 mediated cell-cell fusion