Benzoxadiazoles
OCC2c3ccccc3-c3ccccc23)C(O)=O)CC1 | 100mg | 632809718](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000127212.jpg-250.jpg)
eMolecules 204058-25-3 | Fmoc-Ala(1-Boc-piperidin-4-yl)-OH | Ambeed | MFCD01321423 | 494.588 | C28H34N2O6 | 98.000 | CC(C)(C)OC(=O)N1CCC(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)CC1 | 100mg | 632809718
Fmoc-Ala(1-Boc-piperidin-4-yl)-OH | Ambeed | 204058-25-3 | MFCD01321423 | 494.588 | C28H34N2O6 | 98.000 | CC(C)(C)OC(=O)N1CCC(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)CC1 | 100mg | 632809718
Medchemexpress LLC A 410099.1, amine-Boc hydrochloride | 2374122-37-7 | 99.7% | C32H50ClN5O5 | 10MG
A 410099.1, amine-Boc hydrochloride is a Boc-protected amine hydrochloride derivative used as a functionalized IAP ligand and building block in PROTAC synthesis, including applications targeting Bruton's tyrosine kinase (BTK). Supplied for research use, it is characterized for solubility in DMSO and requires appropriate storage to maintain stability.
- High purity: 99.7% (reported)
- Boc-protected amine with an accessible amine functional handle for conjugation
- White to off-white solid suitable for synthetic applications
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance may be required
- Recommended storage: protect from light; use cold storage for solutions
- Available in small mg quantities for research-scale synthesis
Medchemexpress LLC Nbd-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 100 MG
NBD-557 is a small molecule organic compound identified as a potent HIV-1 inhibitor. It targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4, without affecting later stages of the HIV-1 life cycle such as reverse transcriptase, integrase, or protease.
- Potent cell and virus-cell fusion inhibitory activity
- Active against both X4 and R5 viruses in CXCR4 and CCR5 expressing cell lines
- Binds to unliganded HIV-1 gp120
- Active against laboratory-adapted strains and primary isolates of HIV-1
Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | 428.40 | 50 MG
NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. It binds to HIV-1 gp120 and demonstrates potent antiviral activity (EC50 < 200 nM). It is active against HIV-1 in single-cycle (TZM-bl cells) and multi-cycle (MT-2 cells) assays.
- Potent HIV-1 entry antagonist with an IC50 of 89 nM
- Binds to HIV-1 gp120
- Demonstrates potent antiviral activity (EC50 < 200 nM)
- Prevents HIV-1 mediated cell-cell fusion
Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | 50 MG
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist. It binds to HIV-1 gp120 and demonstrates significant antiviral activity. This compound exhibits low cytotoxicity with a CC50 >100 μM, making it suitable for various research applications.
- Potent HIV-1 entry antagonist with IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses
- Binds to HIV-1 gp120
- Exhibits potent antiviral activity
- Low cytotoxicity (CC50 > 100 μM)
- Anti-HIV-1 activity (IC50=0.16 μM) in single-cycle (TZM-bl cells) assay
- No induced toxicity in U87-CD4-CXCR4 cell line at assay doses
Medchemexpress LLC 7-nitro-2,1,3-benzoxadiazol-4-ylamine | 10199-91-4 | 96.7% | 10 MG
NBD-amine (7-nitro-2,1,3-benzoxadiazol-4-ylamine) is a fluorogenic amine used as a fluorescent probe and a synthetic building block for labeling and sensing applications. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments. CAS 10199-91-4; purity ~96.7%.
- Fluorogenic amine that enhances fluorescence in hydrophobic environments.
- Useful for labeling, sensing, and probe development.
- Soluble in DMSO at 31.25 mg/mL; ultrasonic agitation may be needed.
- Powder stable at -20°C for up to 3 years.
- Molecular weight 180.12 g/mol; formula C6H4N4O3.
Medchemexpress LLC Apelin-16, human, bovine acetate | 99.8% | 2010.37 | 1 MG
Apelin-16, human, bovine acetate is a biologically active peptide.
- Endogenous ligand for the G-protein-coupled APJ receptor.
- Produced as a pre-proprotein of 77 amino acids.
- One of the active fragments of Apelin.
Medchemexpress LLC NBD-557 | 333352-59-3 | 99.4% | C17H24BrN3O2 | 50 MG
NBD-557 is a potential HIV-1 inhibitor, exhibiting potent cell fusion and virus-cell fusion inhibitory activity. This small molecule targets viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4, without affecting later stages of the HIV-1 life cycle like reverse transcriptase, integrase, or protease. It is active against both X4 and R5 viruses, and effective against HIV-1 laboratory-adapted strains, including an AZT-resistant strain, and HIV-1 primary isolates.
- Targets HIV-1 entry by inhibiting gp120 binding to CD4
- Does not inhibit reverse transcriptase, integrase, or protease
- Active against X4 and R5 viruses
- Effective against HIV-1 laboratory-adapted and primary isolates
- Binds to unliganded HIV-1 gp120
- For research use only
Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid (ammonium) | 84806-27-9 | 99.0% | 25 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label primarily used for detecting dissolved thiol-disulfide compounds such as Cys and GSH. It is suitable for various laboratory applications requiring fluorescence-based detection.
- Fluorescent label for thiol-disulfide detection
- Used with Cys and GSH
- Research use only
- Excitation wavelength range: 451-495 nm Blue
- Emission wavelength range: 451-495 nm Blue
Medchemexpress LLC 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | 98.8% | 5 MG