Benzoxadiazoles

Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2508.5 g/mol | C106H178N6O55Na4 | 1mg

Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]

Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2,528.55 g/mol | C106H182N6O56·4Na | 100ug

Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]

Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 98.0% | 494.7 g/mol | C25H43NaO6S | 1MG

INT-767 is a semisynthetic bile acid-derived small molecule used in preclinical research as a potent dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5. It modulates bile acid signaling and has been studied in liver and metabolic disease models in vitro and in vivo.

Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MM 1ML

INT-767 is a research-grade dual farnesoid X receptor (FXR) and TGR5 agonist with reported mean EC50 values of 30 nM (FXR) and 630 nM (TGR5). It is supplied as a white to off-white solid and is available as a 10 mM solution in DMSO. Molecular formula C25H43NaO6S; molecular weight 494.66 g/mol. Intended for laboratory research use only.

• Potent dual FXR and TGR5 agonist with EC50s of 30 nM and 630 nM, respectively.
• High purity suitable for research applications.
• Available as solid or 10 mM DMSO solution for convenience.
• Highly soluble in DMSO and water according to manufacturer data.
• Stable under recommended storage: solid at 4°C; in solution at -80°C for long-term storage.
• Used in studies of bile acid signaling, metabolic disease, and liver injury models.

Medchemexpress LLC Int-767 | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MG

INT-767 is a semisynthetic dual farnesoid X receptor (FXR) and TGR5 (GPBAR1) agonist used in preclinical research to modulate bile acid signaling, liver, and metabolic pathways. The compound shows mean EC50s of 30 nM for FXR and 630 nM for TGR5, and is supplied as the sodium salt with high reported purity.

Medchemexpress LLC 6α-ethyl-3α,7α,23-trihydroxy-24-nor-5β-cholan-23-sulfate | 1000403-03-1 | >98.0% | 494.66 g·mol⁻1 | C25H43NaO6S | 50MG

INT-767 is a synthetic dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5 (GPBAR1), used as a research reagent in preclinical studies of liver and metabolic disease. Reported activity includes mean EC50s of 30 nM (FXR) and 630 nM (TGR5); CAS 1000403-03-1; molecular formula C25H43NaO6S; molecular weight 494.66 g·mol⁻1. Typical supplier-reported purity is >98%. Material is for research use only and not for human therapeutic use.

• Dual FXR and TGR5 agonist for bile-acid signaling studies.
• Well-characterized potency: EC50 30 nM (FXR) and 630 nM (TGR5).
• High reported purity suitable for in vitro and in vivo experiments.
• Supplied as the sodium-sulfate derivative with defined molecular weight.
• Widely used in preclinical models of liver injury, steatosis, and metabolic regulation.
• For research use only; not for clinical or human use.