Benzoxazines
TARGETMOL CHEMICALS INC TUNICAMYCIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bacteria yeasts fungi and viruses and has anti-cancer activity. purity: 98%
AdipoGen WSP1
Chemical. CAS 1352750-34-5. Formula C33H21NO6S2. MW 591.65. Synthetic Hydrogen sulfide H2S is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
Amsbio LLC Human SK-Mel-5 / Luciferase & GFP Stable Cells
Human SK-Mel-5 / Luciferase & GFP Stable Cells
AdipoGen 7-Azido-4-methylcoumarin
Chemical. CAS 95633-27-5. Formula C10H7N3O2. MW 201.18. Synthetic 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin AMC with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 SULT1A1. 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5-phosphate PLP-dependent enzymes e.g. cystathionine beta-synthase CBS, cystathionine gamma-lyase CGL and tryptophan synthase TS and to identify novel cystathionine beta-synthase CBS inhibitors and activators.
TARGETMOL CHEMICALS INC MRTX0902 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM. purity: 98%
TARGETMOL CHEMICALS INC APRICITABINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 uM) the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase (alpha) (beta) and (gamma) with Ki values of 300 uM 12 uM and 112.25 uM respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients with good tolerability and low selective resistance. purity: 100%
TARGETMOL CHEMICALS INC VALEPOTRIATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates a new class of cytotoxic and antitumor agents they are very potent cytotoxic agents for the HTC hepatoma cells. Valepotriates may have a potential anxiolytic effect on the psychic symptoms of anxiety. purity: 99%