Benzoxazines
Medchemexpress LLC Cinnabarinic acid | 606-59-7 | 99.9% | 300.22 | 100 MG
Cinnabarinic acid is a specific orthosteric agonist of mGlu4, interacting with residues of the glutamate binding pocket of mGlu4, and has no activity at other mGlu receptors. It is an endogenous metabolite of the kynurenine pathway of tryptophan and induces cell apoptosis.
- Specific orthosteric agonist of mGlu4.
- Interacts with residues of the glutamate binding pocket of mGlu4.
- No activity at other mGlu receptors.
- Endogenous metabolite of the kynurenine pathway of tryptophan.
- Induces cell apoptosis.
- Human endogenous metabolite.
- Reduces cAMP formation in a concentration-dependent manner with excellent potency and efficacy.
Medchemexpress LLC Resorufin β-D-galactopyranoside | 95079-19-9 | MFCD00064055 | 98.3% | 375.33 | C18H17NO8 | 5 MG
Resorufin-β-D-galactopyranoside is a fluorogenic substrate for β-galactosidase that releases resorufin, a red fluorescent reporter, upon enzymatic hydrolysis. It is provided as a high-purity solid suitable for biochemical and cell-based assays, soluble in DMSO, and compatible with standard fluorescence detection methods.
- Fluorogenic substrate that produces resorufin upon hydrolysis
- High purity for reliable assay performance
- Soluble in DMSO; sonication and warming improve solubility
- Storage-stable when kept dry; solvent-storage recommendations available
- Suitable for enzyme kinetics, reporter assays, and cell-based assays
Medchemexpress LLC 7- Diethylamino -4- 25mg
7-(Diethylamino)-4-(hydroxymethyl)coumarin (compound 10) is an organic compound that can be used as a photosensitizer in organic synthesis[1]
Abcam Cinnabarinic acid, Endogenous mGlu4 selective agonist, 10MG
MW 300.22 Da, Purity >98%. Endogenous selective mGlu4 agonist; generated by autoxidation of the tryptophan metabolite 3-hydroxyanthranilic acid. Activates mGlu4 receptors in transiently transfected HEK293 cells, and is devoid of activity on other mGlu receptor subtypes (mGlu1, 2, 5, 6, 7, and 8). Protects against NMDA-induced excitotoxic cell death.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ResorufIn benzyl ether 10mg
A fluorometric probe that acts as a substrate for CYP3A4; typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds and to predict potential drug-drug interactions
TARGETMOL CHEMICALS INC CUCURBITACIN E 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cucurbitacin E has prevention of neurodegeneration it has potent anti-proliferative antineoplastic anti-inflammatory and analgesic actions. purity: 98%
TARGETMOL CHEMICALS INC TUCIDINOSTAT 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor with IC50s of 95 160 67 and 78 nM less active on HDAC8/11 (IC50 733/432 nM) and shows no effect on HDAC4/5/6/7/9. purity: 97%
![Amsbio LLC Neuraminidase isozyme S [Reagent for studies of gangliosides]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502566245.png-250.jpg)
Amsbio LLC Neuraminidase isozyme S [Reagent for studies of gangliosides]
Neuraminidase isozyme S [Reagent for studies of gangliosides]
