Benzoxazines
Abcam Cinnabarinic acid, Endogenous mGlu4 selective agonist, 50MG
MW 300.22 Da, Purity >98%. Endogenous selective mGlu4 agonist; generated by autoxidation of the tryptophan metabolite 3-hydroxyanthranilic acid. Activates mGlu4 receptors in transiently transfected HEK293 cells, and is devoid of activity on other mGlu receptor subtypes (mGlu1, 2, 5, 6, 7, and 8). Protects against NMDA-induced excitotoxic cell death.
The product is subject to the following: Abcam Restricted Use Statement
eMolecules 25688-63-5 | 2-(DIETHYLAMINO)-2-METHYLPROPAN-1-OL | MFCD22421580 | 1g
Ambeed | 22-Diethoxyethanol | 1g | 525018903 | A120630 | 621-63-6 | MFCD00051486 | 134.175 | C6H14O3
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eMolecules 30721-88-1 | 6-Dimethylamino-pyridine-2-carboxylic acid | J & W PharmLab LLC | MFCD13188975 | 166.180 | C8H10N2O2 | 96.000 | CN(C)c1cccc(n1)C(O)=O | 5g | 289355231
6-Dimethylamino-pyridine-2-carboxylic acid | J & W PharmLab LLC | 30721-88-1 | MFCD13188975 | 166.180 | C8H10N2O2 | 96.000 | CN(C)c1cccc(n1)C(O)=O | 5g | 289355231
eMolecules 28611-39-4 | 4-(Dimethylamino)benzeneboronic acid | Apollo Scientific | MFCD01074642 | 165.000 | C8H12BNO2 | 97.000 | CN(C)c1ccc(cc1)B(O)O | 1g | 562441802
4-(Dimethylamino)benzeneboronic acid | Apollo Scientific | 28611-39-4 | MFCD01074642 | 165.000 | C8H12BNO2 | 97.000 | CN(C)c1ccc(cc1)B(O)O | 1g | 562441802
Medchemexpress LLC Gallocyanine (chloride) | 1562-85-2 | 92.0% | 25 MG
Gallocyanine chloride is a synthetic blue dyestuff being investigated as a potential agent for Alzheimer's disease and related neurodegenerative tauopathies. It functions by inhibiting DKK1/LRP6 interaction with an IC50 of 6.38 μM, which in turn activates the Wnt signaling pathway and leads to β-catenin accumulation. This compound also demonstrates anti-metastasis, anti-inflammatory, and anti-fibrosis activities. Additionally, Gallocyanine chloride can be employed as a fluorescent probe for detecting superoxide anion radicals.
- Potential research agent for Alzheimer's disease and neurodegenerative tauopathies
- Inhibits DKK1/LRP6 interaction
- Activates Wnt signaling pathway
- Causes β-catenin accumulation
- Exhibits anti-metastasis activity
- Exhibits anti-inflammatory activity
- Exhibits anti-fibrosis activity
- Can be used as a fluorescent probe for superoxide anion radical detection
Medchemexpress LLC 7-Ethoxyresorufin (Resorufin ethyl ether) | 5725-91-7 | 99.6% | 25 MG
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, particularly CYP1A1. It also exhibits inhibitory effects on NO synthase. This product is intended for research use only and is not sold to patients.
- Fluorometric substrate for cytochrome P450, especially CYP1A1.
- Competitive inhibitor of cytochrome P450, particularly CYP1A1.
- Inhibits NO synthase.
Cayman Chemical ResorufIn Acetate 50mg
A fluorometric probe that acts as a substrate for ALDH1A1 esterase activity and chymotrypsin
Cayman Chemical ResorufIn benzyl ether 1mg
A fluorometric probe that acts as a substrate for CYP3A4; typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds and to predict potential drug-drug interactions
Sigma Aldrich Fine Chemicals Biosciences Resazurin sodium salt cert25G
SODIUM Resazurin sodium salt cert25G
TARGETMOL CHEMICALS INC CGP52411 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CGP52411 is an orally active and ATP-competitive inhibitor of EGFR (IC50 0.3 uM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of (beta)-amyloid A(beta)42 fibril aggregates. CGP52411 can be used in studies about Alzheimer's diseases. purity: 99%
Eagle Biosciences Inc Complement Factor H ELISA Assay Kit, 1 x 96 wells
Complement Factor H ELISA Assay Kit, 1 x 96 wells
Cell Signaling Technology Na,K-ATPase alpha-1 (D4Y7E) Rabbit mAb (BSA and Azide Free) 100 ug
Na,K-ATPase alpha-1 (D4Y7E) Rabbit mAb (BSA and Azide Free) 100 ug