Biotin and derivatives
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | ≥97.0% | 400.38 g/mol | C16H24N4O8 | 25 MG
NOTA-NHS ester is a bifunctional chelator derivative used for fluorescent labeling and radiolabeling (radionuclide-drug conjugates). It contains an activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines and a NOTA chelator for radiometal coordination. Supplied for research use only.
- Activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines.
- NOTA chelator for stable binding of radiometals.
- Purity ≥97.0%.
- CAS number 1338231-09-6.
- Molecular formula C16H24N4O8; molecular weight 400.38 g/mol.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 | C10H16N2O3S | 25 MG
L-biotin is the unnatural enantiomer of biotin and is used as a biochemical research reagent. It is provided as a white to off-white solid with reported high purity and has been observed to bind streptavidin in laboratory assays.
- High purity suitable for research applications.
- White to off-white solid, easy to handle and store.
- Soluble in DMSO at high concentration for in vitro use.
- Available in small solid quantities appropriate for bench-scale experiments.
- Stable when stored frozen as a powder to extend shelf life.
Medchemexpress LLC m-PEG14-NHS ester | 00-00-0 | 95.0% | C34H63NO18 | 10MG
m-PEG14-NHS ester is a methoxy-terminated polyethylene glycol (PEG) reagent bearing an N-hydroxysuccinimide (NHS) active ester. Supplied as a solid for laboratory use, it is intended for use as a PROTAC linker or for PEGylation to attach PEG chains to amine-containing molecules via stable amide bonds.
- Methoxy-terminated PEG with an NHS active ester.
- Reacts with primary amines to form stable amide bonds.
- Molecular weight ~773.86 Da.
- Chemical formula C34H63NO18.
- Purity ≥95.0%.
- White to off-white solid appearance.
- Store sealed, away from moisture and light; in solvent: -80°C for 6 months, -20°C for 1 month.
- Available in small research pack sizes.
Medchemexpress LLC Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate | 00-00-0 | 98.0% | C38H66F3N13O11S | 10MG
Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate is an azide-containing biotinylated reagent for click chemistry labeling of proteins. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) to conjugate with alkyne-bearing probes, enabling detection of protein modification sites. Intended for research use.
- Contains an azide group for CuAAC and SPAAC reactions.
- Biotin tag enables affinity detection and signal amplification.
- PEG3 linker provides hydrophilicity and spacer flexibility.
- High purity (98.0%) suitable for labeling applications.
- White to off-white solid with recommended handling precautions.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at -20°C; in solvent store at -80°C for long-term stability.
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin 1g
Sulfo-NHS-SS-11-Biotin is an amine-reactive water-soluble biotinylation reagent containing an N-hydroxysulfosuccinimide (Sulfo-NHS) active ester group and a cleavable disulfide bond The Sulfo-NHS moiety reacts specifically with primary amines in proteins peptides or other biomolecules forming stable amide linkages This reagent introduces a disulfide-containing spacer arm enabling subsequent selective cleavage under reducing conditions for release of biotinylated molecules It is commonly employed in affinity chromatography immunoprecipitation experiments cell surface protein labeling and target identification allowing isolation purification or detection of biomolecules through streptavidin or avidin affinity interactions
Medchemexpress LLC M-PEG16-NHS ester | 2563873-83-4 | MFCD13184971 | ≥97.0% | 861.97 | C38H71NO20 | 250mg
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups[1]
Medchemexpress LLC m-PEG1-NHS ester 250mg | 1027371-75-0 | 201.18 g/mol | C8H11NO5 | 250 MG
m-PEG1-NHS ester is a PEG/alkyl/ether-based N-hydroxysuccinimide (NHS) ester linker used for assembling proteolysis targeting chimeras (PROTACs) and for amine-directed bioconjugation. Supplied as a solid, it provides a short PEG spacer with an activated ester for efficient coupling in synthetic workflows.
- PEG/alkyl/ether-based linker for PROTAC synthesis.
- N-hydroxysuccinimide ester reactive toward primary amines.
- Molecular weight 201.18 g/mol.
- Chemical formula C8H11NO5.
- Purity 95.0%.
- Appearance white to light yellow solid.
- Storage: powder -20°C (3 years); in solvent -80°C (6 months), -20°C (1 month).
- Available package size 250 MG.
Medchemexpress LLC GFRAL Human Biotin 50ug | 50ug
The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake energy expenditure and body weight in response to metabolic and toxin-induced stress GFRAL binds to its ligand GDF15 interacts with RET and activates the MAPK and AKT signaling pathways GFRAL Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived GFRAL protein expressed by HEK293 with C-Avi C-His labeled tag