Biotin and derivatives
TARGETMOL CHEMICALS INC DOTA-NHS-ester 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. DOTA-NHS-ester is a linker for affibody molecules with applications in small animal PET, SPECT, and CT. It can be used to label radiotherapeutic agents or imaging probes for tumor detection. Purity ≥98%
TARGETMOL CHEMICALS INC Biotin LC hydrazide 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Biotin LC hydrazide (BACH) is a modification reagent of long-chain protein. Biotin LC hydrazide transforms periodate-oxidized glycoproteins and can be used to target glycoproteins and glycans. Purity 99.4%
Medchemexpress LLC Rhodamine B NHS ester | 144700-55-0 | 96.9% | 576.08 | C32H34ClN3O5 | 10 MG
Rhodamine B NHS ester is an N-hydroxysuccinimide (NHS) activated fluorescent dye for covalent labeling of primary amines in proteins, peptides, and other biomolecules. It forms stable amide bonds to introduce a rhodamine fluorophore for fluorescence microscopy, flow cytometry, and biochemical assays.
- NHS-activated for efficient and selective amine coupling.
- Bright rhodamine fluorescence suitable for microscopy and flow cytometry.
- Molecular weight 576.08 g/mol and formula C32H34ClN3O5.
- High purity (~96.9%) for reliable labeling performance.
- Available in small research pack sizes for convenient use.
Medchemexpress LLC BHQ-1 NHS | 916753-61-2 | C30H31N7O7 | 5 MG
BHQ-1 NHS is a fluorescent dye used for research purposes. It is directly labeled by fluorescently labeled nucleotide and is not intended for patient use.
- Fluorescent dye
- Purity 96.65%
- Solid appearance
- Brown to black color
- Molecular weight 601.61
- Used in cell staining analysis
- Used in cell function analysis
- Applicable in nucleic acid dyes
Medchemexpress LLC Sulfo-cyanine7 NHS ester (TEA) | 95.8% | 907.15 g/mol | C47H62N4O10S2 | 10 MG
Sulfo-Cyanine7 NHS ester (TEA) is a sulfonated near-infrared fluorescent dye supplied as an NHS-activated ester (triethylammonium salt) for covalent labeling of primary amines on proteins and peptides. It enables strong NIR fluorescence for in vitro labeling, imaging, and assay development, and is supplied as a stable solid with recommended cold, dry storage.
- Amine-reactive NHS ester for stable covalent conjugation.
- Near-infrared fluorescence suitable for imaging and detection.
- Water-soluble sulfonated dye for improved solubility.
- Supplied as a solid; store sealed at 4°C and protect from light.
- High purity appropriate for labeling applications.
Medchemexpress LLC Cyclooctyne-O-NHS ester | 1425803-45-7 | 95.0% | 279.29 g/mol | C14H17NO5 | 25 MG
Cyclooctyne-O-NHS ester is an NHS-activated cyclooctyne reagent used for bioconjugation and antibody-drug conjugate synthesis. It couples to primary amines to form stable amide bonds and participates in strain-promoted azide-alkyne cycloaddition (click chemistry) workflows.
- N-hydroxysuccinimide (NHS) activated ester for efficient amide coupling.
- Strained cyclooctyne enables copper-free click reactions with azides.
- Molecular formula C14H17NO5 and molecular weight 279.29 g/mol.
- High purity for research use (95.0%).
- White to off-white solid; store at -20°C under nitrogen.
Medchemexpress LLC Bis-PEG10-NHS ester | 2221949-02-4 | 95.0% | 752.76 | C32H52N2O18 | 25 MG
Bis-PEG10-NHS ester is a PEG/alkyl/ether-based bifunctional NHS ester linker used for amine-reactive bioconjugation in the synthesis of PROTACs and antibody-drug conjugates. Supplied for research use only, it has a molecular weight of 752.76 g/mol and a listed purity of 95.0%.
- NHS ester reactive group for amine coupling.
- PEG10 spacer provides water solubility and flexibility.
- Suitable for PROTAC and ADC synthesis and other bioconjugation applications.
- Available in small milligram pack sizes for research use.
- Storage recommendations: pure form -20°C; in solvent -80°C (6 months), -20°C (1 month).
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | 99.89% | C33H56N4O14S | 100 MG
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins by linking a ligand for an E3 ubiquitin ligase and a ligand for the target protein.
- For research use only
- Available in various quantities
- Multiple documentation types available
- White to off-white solid appearance
Medchemexpress LLC N-succinimidyl-3-(2-pyridyldithio)butyrate | 107348-47-0 | MFCD28398150 | 98.3% | 326.4 g/mol | C13H14N2O4S2 | 1 G
PPC-NHS ester (N-succinimidyl-3-(2-pyridyldithio)butyrate, CAS 107348-47-0) is an NHS-activated cleavable linker reagent used for conjugating small molecules to proteins and antibodies. It reacts with primary amines to form stable amide bonds and contains a pyridyldisulfide moiety that enables controlled cleavage under reducing conditions, making it suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Reacts with primary amines to form stable amide bonds.
- Contains a pyridyldisulfide cleavable linkage for controlled release under reducing conditions.
- High purity suitable for conjugation workflows (≈98.3%).
- Compatible with common aqueous and organic conjugation conditions.
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | >97.0% | 501.49 g/mol | C20H31N5O10 | 250 MG
DOTA-NHS-ester is an NHS-activated DOTA chelator used to conjugate the DOTA moiety to biomolecules (for example, peptides, proteins, and affibodies) to enable radiolabeling for PET, SPECT, and radiotherapeutic research. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.
- NHS-activated DOTA chelator for amine conjugation.
- High purity (>97.0%).
- Molecular weight 501.49 g/mol; formula C20H31N5O10.
- Soluble in DMSO (50 mg/mL); ultrasonic assistance recommended.
- Storage: sealed, away from moisture; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for radiolabeling research (PET/SPECT); not for human use.
Medchemexpress LLC Diazo biotin-PEG3-azide | 1339202-33-3 | 95.5% | C33H45N9O7S | 25 MG
Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that have DBCO or BCN groups. PROTACs themselves consist of two different ligands linked together, one targeting an E3 ubiquitin ligase and the other a specific protein, leveraging the intracellular ubiquitin-proteasome system to degrade target proteins selectively.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
Medchemexpress LLC Biotin-PEG-Biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 25 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Chem-Impex International, Inc. (+) Biotinyl-6-aminohexanoic acid | 72040-64-3 | MFCD00144853 | 250MG
(+) Biotinyl-6-aminohexanoic acid, 72040-64-3, MFCD00144853, 250MG
Medchemexpress LLC Biotin-PEG3-acid 100mg | 252881-76-8 | 100 MG
Biotin-PEG3-acid is a biotin-labeled polyethylene glycol (PEG3) linker containing a terminal carboxylic acid. It is supplied as a purified research-grade small molecule for use in PROTAC synthesis and biotinylation applications.
- Biotin-labeled PEG3 linker with terminal carboxylic acid.
- Designed for PROTAC synthesis and biotinylation workflows.
- High purity, 98.0%.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at 4°C; in solution store at -80°C for long-term stability.
- Available in 100 MG and larger pack sizes for research use.