Biotin and derivatives
Medchemexpress LLC Bis-PEG21-NHS ester | 2221948-98-5 | 99.9% | 500 MG
Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker primarily used in the synthesis of PROTACs. It also serves as a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
- PEG/Alkyl/ether-based linker
- PROTAC linker for targeted protein degradation
- Cleavable ADC linker
- Utilizes the ubiquitin-proteasome system
- Suitable for PROTACs synthesis
- Suitable for ADC synthesis
Apexbio Technology LLC Cy3 NHS ester (non-sulfonated) 5mg
Cy3 NHS ester (non-sulfonated) is an amine-reactive fluorescent cyanine dye commonly utilized in labeling biomolecules via covalent conjugation to primary amines As a cyanine derivative its fluorescence emission occurs at approximately 570 nm upon excitation near 550 nm allowing detection in the orange spectral region using standard TRITC filter sets commonly integrated in fluorescence microscopy imaging systems and spectroscopic instruments The dye s labeling procedure requires organic solvents such as DMF or DMSO due to its limited aqueous solubility In biomedical research Cy3 NHS ester is routinely employed for labeling peptides proteins nucleic acids and oligonucleotides facilitating visualization and tracking in biomolecular assays cell imaging gel electrophoresis analyses and flow cytometry experiments
Sigma Aldrich Fine Chemicals Biosciences Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 100MG
![Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl) | 2363756-34-5 | 98.8% | 664.81 g/mol | C28H52N6O10S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000283161.png-250.jpg)
Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl) | 2363756-34-5 | 98.8% | 664.81 g/mol | C28H52N6O10S | 100 MG
Biotin-PEG8-azide is a biotin-labeled polyethylene glycol (PEG8) linker with a terminal azide group used for biotinylation of macromolecules via azide-alkyne cycloaddition (click chemistry). It enables efficient conjugation for affinity capture, detection, or immobilization in biochemical assays.
- Provides a PEG8 spacer to improve solubility and reduce steric hindrance.
- Contains a terminal azide for copper-catalyzed or strain-promoted click reactions.
- Facilitates biotin labeling for high-affinity capture with streptavidin or avidin reagents.
- High purity (98.8%) suitable for research applications.
- Off-white to light yellow oil with storage recommendations for long-term stability.
eMolecules 756525-90-3 | m-PEG8-NHS ester | ChemScene | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 859848158
m-PEG8-NHS ester | ChemScene | 756525-90-3 | MFCD13184969 | 509.549 | C22H39NO12 | 98.000 | COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 859848158
Sigma Aldrich Fine Chemicals Biosciences Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 10MG
Biotin disulfide N-hydroxysuccinimide ester >98%, powder | Purity: >98% | Mol Wt: 575.72 | 142439-92-7 | MFCD00466919 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Biotin 3 sulfo N hydroxysu50MG
Biotinavidin second antibody signal systems involve the conjugation of biotin to a secondary antibody. Once the secondary antibody binds to a target primary antibody in an immunochemical assay the signal is developed by allowing avidin which has been conjugated to an enzyme or signal molecule to bind to the antibody associated biotin molecule.
Medchemexpress LLC DBCO-PEG12-NHS ester | 2093934-94-0 | 96.1% | C50H71N3O18 | 25 MG
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups. PROTACs utilize the ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features a DBCO group for SPAAC
- Facilitates strain-promoted alkyne-azide cycloaddition with azide groups
- PROTACs utilize the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC PCSK9 Human Biotin 5ug | 5ug
The PCSK9 protein is an important regulator of plasma cholesterol homeostasis affecting LDL receptor family members such as LDLR and VLDLR It promotes their intracellular degradation and enhances hepatic LDLR degradation through non-proteolytic mechanisms PCSK9 Protein Human (Biotinylated HEK293 D374Y His-Avi) is the recombinant human-derived PCSK9 protein expressed by HEK293 with C-Avi C-His labeled tag and D374Y mutation
Medchemexpress LLC Nhs-peg1-ss-peg1-nhs | 1688598-83-5 | MFCD32644554 | 98.0% | 436.41 | 100 MG
NHS-PEG1-SS-PEG1-NHS is a reversible linker designed for conjugating biomacromolecules with active small molecules. It is suitable for applications involving proteins, liposomes, or nanoparticles, and is intended for research use only.
- Reversible linker for biomacromolecule conjugation
- Can be used with active small molecules
- Applicable in proteins, liposomes, or nanoparticles
- For research use only