Biotin and derivatives
Apexbio Technology LLC BIOTIN-PEG1-NH2-100MG
Biotin-PEG1-NH2 (CAS No 811442-85-0) is frequently used in biomedical research due to its utility in bioconjugation applications This compound combines biotin a naturally occurring vitamin that binds strongly to streptavidin with a polyethylene glycol (PEG) spacer which enhances solubility and reduces steric hindrance in conjugation reactions It primarily targets pathways involving avidin-biotin interactions known for their high affinity and specificity This mechanism facilitates various in vitro activities often characterized by nanomolar to low micromolar efficacy Biotin-PEG1-NH2 is widely employed in studying cellular mechanisms conducting animal studies and screening potential therapeutic agents Its versatility allows for application in diverse cell models and experimental systems with concentrations typically tailored to the research design requirements
Medchemexpress LLC Mal-PEG24-NHS ester | 2226733-37-3 | MFCD11041160 | 95.0% | C62H111N3O31 | 10MG
Mal-PEG24-NHS ester is a polyethylene glycol (PEG)-based bifunctional linker bearing a maleimide and an N-hydroxysuccinimide (NHS) ester. It enables thiol-to-maleimide and amine-to-NHS conjugation for assembly of PROTACs and other bioconjugates; supplied as a colorless to light-yellow oil with high purity and good aqueous solubility.
- Enables thiol and amine conjugation via maleimide and NHS ester chemistry.
- Long PEG24 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable reaction performance.
- High aqueous solubility simplifies handling and formulation.
- Suitable for PROTAC synthesis and general bioconjugation workflows.
Chem-Impex International, Inc. Biotin-N-hydroxysuccinimide | 35013-72-0 | MFCD00078531 | 5G
Biotin-N-hydroxysuccinimide, 35013-72-0, MFCD00078531, 5G
TARGETMOL CHEMICALS INC NSP-SA-NHS 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. NSP-SA-NHS is a chemiluminescent acridinium ester that can be used for immunoassays. Purity 98.42%
Medchemexpress LLC Bz-(Me)Tz-NHS | 1454558-58-7 | MFCD00076258 | C₁₉H₂₀N₅O₅S | 25 MG
Bz-(Me)Tz-NHS is a click chemistry reagent that contains a methyltetrazine group. It functions as a 3rd generation Click-Linker for Cu-free click conjugation, primarily used in antibody-drug conjugate (ADC) related research.
- Contains a methyltetrazine group
- Functions as a 3rd generation Click-Linker
- Designed for Cu-free click conjugation
- Used in antibody-drug conjugate (ADC) related research
Medchemexpress LLC PC azido-PEG3-NHS carbonate ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 | C26H36N6O13 | 100 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker reagent that selectively labels primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It contains an azide for bioorthogonal click chemistry and an N-hydroxysuccinimide (NHS) carbonate group for efficient coupling; the photocleavable moiety enables light-triggered release of attached cargos. Supplied at high purity for research use.
- Photocleavable linker enabling light-triggered release
- Reacts with primary amines via NHS carbonate chemistry
- Includes an azide for bioorthogonal click reactions
- High purity suitable for research applications
- Offered in multiple pack sizes, e.g., 100 mg
Medchemexpress LLC DBCO-NHS ester | 1353016-71-3 | 99.5% | 402.40 g/mol | C23H18N2O5 | 100 MG
DBCO-NHS ester is an N-hydroxysuccinimide (NHS) activated ester bearing a dibenzocyclooctyne (DBCO) moiety, used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate construction.
- Non-cleavable ADC linker suitable for bioconjugation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners.
- High purity (reported ~99.5%).
- Physical form: solid; color white to yellow.
- Storage: powder -20°C (3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Molecular formula C23H18N2O5; molecular weight 402.40 g/mol.