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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.
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1,111 – 1,125 of 1,267 results
1,111

Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 5mg, CAS: 142439-92-7.
SDP

NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications

ENCOMPASS_PREFERRED
1,112

Medchemexpress LLC AF647-NHS ester | 407627-60-5 | 99.7% | 956.09 | C40H49N3O16S4 | 10 MG
SDP

AF647-NHS ester is an N-hydroxysuccinimide ester of a far-red fluorescent dye used to covalently label amine-containing biomolecules for fluorescence imaging and detection. It is supplied as a solid optimized for conjugation to proteins, antibodies, and peptides.

  • Far-red excitation at 635 nm (instantaneous 620 nm) suitable for 633-647 nm lasers.
  • High purity by HPLC: 99.74%.
  • Molecular weight 956.09; formula C40H49N3O16S4.
  • Appearance: dark purple to black solid.
  • Storage: long-term at 4 °C sealed; in solvent, -80 °C up to 6 months.
  • Supplied as 10 MG vials.

ENCOMPASS_PREFERRED
1,113

Medchemexpress LLC Amino-PEG11-amine | 479200-82-3 | 95.0% | 100 MG
SDP

Amino-PEG11-amine is a PEG-based PROTAC linker designed to combine mono diethylstilbestrol (DES)-based ligands. This offers an alternative approach for creating more selective and active ER antagonists, useful in the endocrine treatment of breast cancer. The product appears as an oil with a white to off-white color. Its molecular weight is 544.68 and its formula is C24H52N2O11. This product is for research use only and not for sale to patients.

  • PEG-based PROTAC linker
  • Combines mono diethylstilbestrol (DES)-based ligands
  • Supports development of selective ER antagonists
  • Potential for breast cancer endocrine therapy
  • Appears as an oil
  • Color: white to off-white
  • Molecular weight: 544.68
  • Chemical formula: C24H52N2O11
  • For research use only

ENCOMPASS_PREFERRED
1,114

eMolecules​ 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 50mg | 598441767

Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 50mg | 598441767

ENCOMPASS_PREFERRED
1,115

eMolecules​ 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 100g | 490500209

Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 100g | 490500209

ENCOMPASS_PREFERRED
1,116

Medchemexpress LLC Sulfo-NHS-Acetate sodium | 221222-61-3 | 95.0% | C6H6NNaO7S | 25 MG
SDP

Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules designed with two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • Alkyl chain-based PROTAC linker
  • Can be used in the synthesis of PROTACs
  • Targets the intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins

ENCOMPASS_PREFERRED
1,117

Medchemexpress LLC Biotin-PEG-amine (MW 2000) | 90.0% | 50 MG
SDP

Biotin-PEG-amine (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other binds to the target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Exploits the ubiquitin-proteasome system
  • Enables selective degradation of target proteins

ENCOMPASS_PREFERRED
1,118

eMolecules​ 1807518-72-4 | Mal-PEG1-NHS ester | Broadpharm | MFCD26127783 | 310.262 | C13H14N2O7 | 0.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 1g | 802656011

Mal-PEG1-NHS ester | Broadpharm | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 0.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 1g | 802656011

ENCOMPASS_PREFERRED
1,119

Medchemexpress LLC Dspe-biotin | 133695-76-8 | 97.5% | 974.36 | C51H96N3O10PS | 25 MG
SDP

DSPE-Biotin is a biotin-functionalized phospholipid designed to introduce biotin into lipid-based systems such as liposomes and micelles for streptavidin/avidin-mediated capture, labeling, or immobilization in biochemical and biophysical research applications.

  • Biotin functional group enables strong streptavidin/avidin binding.
  • Compatible with incorporation into liposomes, micelles, and other lipid assemblies.
  • High purity (97.5%) supports reproducible experimental results.
  • Solid, off-white to light yellow appearance for easy handling.
  • Soluble in DMSO (≈1.3 mg/mL) with sonication and warming to 60°C.
  • Store protected from light at -20°C; in solvent, store at -80°C for up to 6 months.

ENCOMPASS_PREFERRED
1,120

Medchemexpress LLC DBCO-N-bis(PEG4-NHS ester) | 2639395-38-1 | 96.2% | 995.03 g/mol | C49H62N4O18 | 10 MG
SDP

DBCO-N-bis(PEG4-NHS ester) is a PEG-based bifunctional linker that contains a dibenzocyclooctyne (DBCO) group and two PEG4-NHS ester reactive ends. It is designed for click chemistry applications, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) for protein modification, labeling, and use as a linker in conjugate syntheses.

  • Contains two PEG4-NHS ester groups and one DBCO group.
  • Enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
  • Suitable for protein modification and labeling applications.
  • Molecular weight 995.03 g/mol; formula C49H62N4O18.
  • Purity approximately 96.2%.
  • Available in small quantities (for example, 10 mg) for laboratory use.
  • Storage: pure form -20 °C (long-term); in solvent -80 °C (recommended for extended storage).

ENCOMPASS_PREFERRED
1,121

Medchemexpress LLC exo-BCN-NHS carbonat 100mg
SDP

exo-BCN-NHS carbonate carbonate contains BCN group Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups

ENCOMPASS_PREFERRED
1,122

Medchemexpress LLC M-PEG13-NHS ester | 3063847-98-0 | 95.0% | C32H59NO17 | 100 MG
SDP

m-PEG13-NHS ester is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This compound is intended for research use only.

  • PEG-based PROTAC linker
  • Utilized in the synthesis of PROTACs
  • For research use only

ENCOMPASS_PREFERRED
1,123

Medchemexpress LLC Bis-PEG10 N-hydroxysuccinimide ester | 2221949-02-4 | 95.0% | 752.76 g/mol | C32H52N2O18 | 50 MG
SDP

Bis-PEG10 N-hydroxysuccinimide ester is a bifunctional PEG10-based NHS ester linker used for conjugation chemistry. It features two NHS-reactive termini separated by a ten-unit polyethylene glycol spacer, enabling efficient amine coupling, increased aqueous solubility, and flexible linker geometry for targeted conjugate assembly.

  • Two NHS ester reactive groups for amine coupling.
  • Ten-unit PEG spacer for improved solubility and flexibility.
  • Suitable for linker assembly in PROTAC and ADC synthesis.
  • Typical purity 95.0%.
  • Appearance: colorless to off-white oil.
  • Storage: pure form, -20°C; in solvent, -80°C for long-term storage.

ENCOMPASS_PREFERRED
1,124

Medchemexpress LLC CXADR Mouse Biotin 100ug
SDP

CXADR protein is a key component of the epithelial apical junction complex which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML This interaction activates - T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase CXADR Protein Mouse (Biotinylated HEK293 Avi-His) is the recombinant mouse-derived CXADR protein expressed by HEK293 with C-Avi C-6 His labeled tag

ENCOMPASS_PREFERRED
1,125

Medchemexpress LLC DBCO-NHS ester 3 250mg | 1393350-27-0 | 416.43 g·mol⁻1 | C24H20N2O5 | 250 MG
SDP

DBCO-NHS ester 3 is a dibenzocyclooctyne (DBCO)-N-hydroxysuccinimide (NHS) ester reagent used to functionalize primary amines for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation. It enables installation of a DBCO handle for subsequent conjugation to azide-labeled partners.

  • Installs DBCO onto primary amines for SPAAC (copper-free) click chemistry.
  • Suitable for antibody-drug conjugate linker installation, probe labeling, and general bioconjugation.
  • High purity, typically 95.6%, provided as a solid white to off-white powder.
  • Molecular weight 416.43 g·mol⁻1; formula C24H20N2O5.
  • Available in laboratory-scale 250 MG pack size.

ENCOMPASS_PREFERRED