Biotin and derivatives
Apexbio Technology LLC NHS-SS-PH-10MG
NHS-SS-Ph (CAS No 2750799-12-1) is a specialized reagent used in biomedical research primarily for its role in bioconjugation processes It originates from the synthesis of amine-reactive esters linked by a disulfide bond facilitating targeted delivery in various molecular pathways NHS-SS-Ph is often utilized in studies involving protein modification where it exhibits activity in the nanomolar to low micromolar range Its applications are widely observed across in vitro cell models including cancer and stem cell research and in vivo animal studies for drug screening purposes The reagent s utility in these contexts underscores its significance in advancing therapeutic developments and biomarker discovery Experimental concentrations typically depend on the specific research design allowing for tailored investigations based on the study s objectives and conditions
Apexbio Technology LLC Biotin Hydrazide 66640-86-6 500mg
Biotin hydrazide is a hydrazide-functionalized biotin derivative designed to selectively label and detect protein carbonylation an irreversible post-translational modification frequently arising from oxidative stress conditions Protein carbonylation typically results from reactions between protein side chains and reactive oxygen species (ROS) lipid peroxidation metabolites such as -unsaturated -hydroxyalkenals or glycation-mediated oxidative modifications Mechanistically Biotin Hydrazide interacts specifically with protein-bound carbonyl groups through hydrazone formation under mildly acidic conditions (around pH 5 5) without the requirement of additional reducing agents or catalysts Thus Biotin hydrazide facilitates biochemical studies aimed at identifying and characterizing carbonyl-modified proteins in biological samples through biotin-based detection assays and downstream proteomic analysis techniques
Medchemexpress LLC PC azido-PEG3-NHS carbonate ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 | C26H36N6O13 | 100 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker reagent that selectively labels primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It contains an azide for bioorthogonal click chemistry and an N-hydroxysuccinimide (NHS) carbonate group for efficient coupling; the photocleavable moiety enables light-triggered release of attached cargos. Supplied at high purity for research use.
- Photocleavable linker enabling light-triggered release
- Reacts with primary amines via NHS carbonate chemistry
- Includes an azide for bioorthogonal click reactions
- High purity suitable for research applications
- Offered in multiple pack sizes, e.g., 100 mg
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 476.48 g/mol | C19H32N4O10 | 50 MG
Azido-PEG6-NHS ester is a cleavable six-unit polyethylene glycol (PEG) linker containing an azide and an N-hydroxysuccinimide (NHS) ester. It is used as a click-chemistry reagent for conjugation reactions and as a linker in antibody-drug conjugate and PROTAC synthesis.
- Cleavable six-unit PEG linker for bioconjugation.
- Azide group enables CuAAC and SPAAC click reactions.
- NHS ester reacts with primary amines for efficient coupling.
- Molecular weight 476.48 g/mol, formula C19H32N4O10.
- Purity 98.0% and liquid form, colorless to light yellow.
- Store pure material at -20°C; in solvent store at -80°C or -20°C as specified.
- Available in small quantities such as 50 mg for lab-scale use.
Medchemexpress LLC EphA2 Human Biotin 100ug
The EphA2 protein is an important member of the ephrin receptor subfamily that mediates developmental events particularly in the nervous system It has a single kinase domain and an extracellular region that binds ephrin-A ligands EphA2 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived EphA2 protein expressed by HEK293 with C-6 His C-Avi labeled tag
Medchemexpress LLC m-PEG16-NHS ester | 2563873-83-4 | 100mg
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups[1]