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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.

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1

Medchemexpress LLC Biotin-labeled ODN 2395 sodium | 1254617-22-5 | 1 MG
SDP

Biotin-labeled ODN 2395 sodium is a C class oligodeoxynucleotide and a TLR9 agonist. It is used for research purposes to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

  • Is a C class oligodeoxynucleotide
  • Acts as a TLR9 agonist
  • Facilitates evaluation of CpG ODN cellular uptake and localization
  • Designed for use with biotin detection systems and light microscopy

ENCOMPASS_PREFERRED
2

Medchemexpress LLC SPDP-C6-NHS ester | 158913-22-5 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 250MG
SDP

SPDP-C6-NHS ester is an NHS-activated, cleavable linker that contains a disulfide bond and is used for bioconjugation and PROTAC synthesis. The reagent couples to primary amines via its NHS ester and enables reversible linkage through disulfide reduction. It is supplied as a powder with specified storage and stability conditions and is intended for research use only.

  • Cleavable disulfide linker for reversible conjugation
  • NHS ester reactive toward primary amines
  • Suitable for PROTAC synthesis and bioconjugation applications
  • High purity (98.1% as listed)
  • Available in multiple pack sizes, including 250 mg
  • Powder storage recommendations: -20°C for long term, 4°C for shorter term

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 100MG
SDP

SPDP-C6-NHS ester is a heterobifunctional alkyl/ether-based linker bearing an N-hydroxysuccinimide (NHS) ester and a pyridyldithiol moiety, designed for bioconjugation and assembly of bifunctional molecules such as PROTACs. The NHS ester enables amine coupling to form stable amide bonds, while the pyridyldithiol group allows disulfide formation with thiols, providing modular chemistry for linking ligands, payloads, or proteins.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 500MG
SDP

SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that features an NHS-activated ester for amine coupling and a pyridyldisulfide moiety for disulfide conjugation. Supplied as a white to off-white solid, it is used in conjugation chemistry and the synthesis of PROTACs and related bifunctional molecules.

  • Alkyl/ether-based PROTAC linker with an NHS activated ester.
  • Contains a pyridyldisulfide group for disulfide bond formation.
  • High purity: 98.1%.
  • Molecular formula C18H23N3O5S2; molecular weight 425.52.
  • Soluble in DMSO at 50 mg/mL; ultrasonic treatment recommended.
  • Store powder at -20°C for long term; store solutions at -80°C for short term.
  • Available in small-scale solid quantities for research use.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 1G
SDP

Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate is an alkyl/ether-based PROTAC linker containing an N-hydroxysuccinimide (NHS) ester for amine coupling and a pyridyldisulfide moiety for thiol-directed conjugation. It is used in PROTAC and bioconjugation synthesis and features a reducible disulfide that enables controlled cleavage in downstream applications.

  • Provides an NHS ester for efficient conjugation to primary amines.
  • Contains a pyridyldisulfide cleavable disulfide for thiol chemistry.
  • Suitable as a linker in PROTAC and bioconjugation synthesis.
  • Molecular formula C18H23N3O5S2; molecular weight 425.52 g/mol.
  • Soluble in DMSO at approximately 50 mg/mL; may require sonication.
  • Store powder at -20°C for long-term stability; solvent solutions require low-temperature storage.
  • High purity (98.1%) suitable for research applications.

ENCOMPASS_PREFERRED