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Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody targeting to TNFSF15/TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD).
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LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo.
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Davercin (erythromycin cyclocarbonate) is a semi-synthetic macrolide derivative of erythromycin used as a research reagent. It is reported to inhibit bacterial protein synthesis by binding the 50S ribosomal subunit and shows activity against Gram-positive and some Gram-negative organisms, making it useful for microbiology and antibiotic studies.
Macrolide antibiotic derivative active against Gram-positive and some Gram-negative bacteria.
Inhibits protein synthesis through 50S ribosomal binding.
Suitable as a reference standard or reagent in microbiology and antibiotic research.
Provided in small quantities for preparing concentrated stock solutions (for example, 1 mg, 5 mg).
Characterized by CAS 55224-05-0 and molecular formula C38H65NO14.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Davercin (erythromycin cyclocarbonate) is a macrolide antibiotic derivative used as a research reagent. It inhibits bacterial protein synthesis and is reported to be active against Gram-positive and some Gram-negative microorganisms. The product is supplied in solid and solution formats with manufacturer guidance for solvent preparation and handling.
Derivative of erythromycin with antibacterial activity against Gram-positive and some Gram-negative organisms.
Molecular formula C38H65NO14 and molecular weight about 759.92 g/mol.
CAS number 55224-05-0 for unambiguous chemical identification.
Available in solid sizes from 1 mg to 500 mg and as 10 mM solutions in DMSO.
Soluble in DMSO for preparing stock solutions; limited solubility in water.
Intended for laboratory research use; follow the safety data sheet and handling instructions.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Davercin (erythromycin cyclocarbonate) is a semi-synthetic derivative of erythromycin used as an antibacterial research reagent. It inhibits bacterial protein synthesis and is active against Gram-positive and some Gram-negative organisms. Supplied as a solid for laboratory studies and analytical reference.
Derivative of erythromycin with antibacterial activity.
Active against Gram-positive and some Gram-negative organisms.
High purity (98.0%).
Molecular weight 759.92 g/mol and formula C38H65NO14.
White to off-white solid suitable for laboratory use.
Available in small research quantities such as 25 MG.
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Topiramate (CAS 97240-79-4) is an anticonvulsant compound widely investigated for its interactions with multiple neuronal ion channels and neurotransmitter receptors including AMPA kainate and NMDA glutamate receptors as well as GABA A receptors and voltage-gated Na channels In vitro studies demonstrate that at submicromolar concentrations (IC 0 5 M) topiramate selectively inhibits GluR5-containing kainate receptor-mediated excitatory synaptic currents in rat basolateral amygdala neurons and partially attenuates AMPA receptor-mediated responses Electrophysiological assays in cortical slices reveal that topiramate modulates persistent Na currents and shifts steady-state inactivation In animal models topiramate confers dose-dependent neuroprotection in ischemic stroke and elevates seizure thresholds supporting its utility for mechanistic studies of epilepsy and neuroprotection
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