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Filtered Search Results
Medchemexpress LLC PF-06456384 trihydrochloride | 1834610-75-1 | ≥98.0% | 829.18 g·mol⁻¹ | C35H32F3N7O3S2 · 3HCl | 25 MG
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The trihydrochloride salt is a small-molecule research compound described as a highly potent and selective inhibitor of the NaV1.7 voltage-gated sodium channel; it has reported sub-nanomolar activity and is used in preclinical pain model research.
- Highly potent and selective NaV1.7 inhibition (reported IC50 ≈ 0.01 nM).
- Used in preclinical pain models, including the formalin test.
- Supplied as a trihydrochloride salt in white to beige powder form.
- High purity (≥98% by HPLC reported by distributors).
- Solubility: readily soluble in DMSO (~125 mg/mL); limited aqueous solubility (~2 mg/mL reported).
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Medchemexpress LLC Cct365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 10MG
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CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor used for preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation, is orally active in models, and has demonstrated favorable tolerability and pharmacokinetic properties.
- Orally active LOX inhibitor (IC50 = 0.89 μM).
- High purity (98.1%) suitable for biological studies.
- Available in small research pack sizes for in vitro and in vivo use.
- Soluble in DMSO (250 mg/mL); in vivo formulation protocols provided.
- Storage guidance included for solid and solution stability.
- Intended for research use only; not for human administration.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000692262 E-NITROFURAZONE 1G
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MEDCHEMEXPRESS LLC NIFUROXAZIDE 200MG
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501874561 NIFUROXAZIDE 200MG
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Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 g·mol⁻¹ | C18H18ClNO4S3 | 50MG
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CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor intended for research use. It exhibits LOX inhibitory activity in the submicromolar to low-micromolar range, suppresses EGF-driven EGFR (pY1068) and AKT phosphorylation in cellular studies, and has reported favorable pharmacokinetic properties.
- Hydrochloride salt form for improved solubility.
- Reported LOX inhibitory activity with IC50 ≈ 0.89 μM.
- Suppresses EGF-driven EGFR (pY1068) and AKT phosphorylation in cell-based assays.
- High reported purity (~98.1%).
- Available as solid vials and as solution formulations in DMSO.
- For research use only.
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Medchemexpress LLC 1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydrocyclopenta[c]quinolin-8-yl]ethanone | 881639-98-1 | 99.8% | 412.28 g·mol⁻¹ | C21H18BrNO3 | 50 MG
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G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 (G protein-coupled estrogen receptor) with a reported Ki of 11 nM. It is supplied as a research reagent with formula C21H18BrNO3, molecular weight 412.28 g·mol⁻¹, and high reported purity suitable for in vitro signaling studies.
- Selective GPR30 agonist (Ki = 11 nM).
- High purity (99.76%).
- Molecular formula C21H18BrNO3 and molecular weight 412.28 g·mol⁻¹.
- Soluble in DMSO for assay preparation.
- Intended for research use only; not for human use.
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Medchemexpress LLC 2-isopropylphenyl N-(2-naphthalen-2-yl)ethyl carbamate | 1354359-53-7 | MFCD20926355 | 99.5% | 333.42 g/mol | C22H23NO2 | 10 MG
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JW480 is a potent, selective carbamate inhibitor of the serine hydrolase KIAA1363 (AADACL1). It is used as a research reagent to probe KIAA1363 function in lipid metabolism and cancer-relevant cellular pathways, and is supplied with characterization data appropriate for biochemical and cellular studies.
- Selective inhibitor of the serine hydrolase KIAA1363.
- Suitable for biochemical and cell-based assays.
- Carbamate-based small-molecule structure for target engagement studies.
- High purity and defined molecular properties for reproducible results.
- Provided with catalog and registry identifiers for traceability.
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Medchemexpress LLC B022 | 1202764-53-1 | 99.4% | 100 MG
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B022 is a selective NF-κB-inducing kinase (NIK) inhibitor research compound commonly used in biochemical and cellular studies targeting NF-κB signaling pathways. It is provided as a high-purity small-molecule suitable for in vitro experiments.
- Selective inhibition of NF-κB-inducing kinase with low nanomolar potency (Ki ≈ 4.2 nM, IC50 ≈ 15.1 nM).
- High purity: 99.37% as listed by supplier.
- Molecular formula C19H16ClN5OS; molecular weight 397.88 g·mol⁻¹.
- Available in small-molecule research sizes, including 100 MG.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Suitable for studies of inflammation, oxidative stress, and liver injury models.
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Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | 393.24 g/mol | C13H6F6NNaO3S | 5 MG
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Batabulin sodium is a sodium salt antitumor research compound that covalently and selectively binds specific β-tubulin isotypes, disrupting microtubule polymerization, inducing G2/M cell-cycle arrest, and triggering apoptotic cell death. Supplied as an off-white to light-yellow solid for in vitro and in vivo research applications.
- Covalently binds to a subset of β-tubulin isotypes.
- Disrupts microtubule polymerization and induces G2/M arrest.
- Induces apoptosis in cell-based assays.
- High reported purity (~99.8%).
- Soluble in DMSO; use freshly opened solvent and ultrasonic assistance if needed.
- Store powder at 4°C; in solution store at -80°C for long-term stability.
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Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | >98.0% | 151.55 g/mol | C3H6ClN3O2 | 100mg
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1-Aminohydantoin hydrochloride (Standard) is the analytical standard of 1-Aminohydantoin hydrochloride (HY-Y0469) This product is intended for research and analytical applications 1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
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Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | ≥98.0% | 151.55 | C3H6ClN3O2 | 25g
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1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
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Medchemexpress LLC Methyl protogracillin | 54522-53-1 | MFCD32197353 | 99.0% | 1079.23 | C52H86O23 | 10 MG
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Methyl protogracillin is a steroidal saponin natural product isolated from the roots of Dioscorea opposite Thunb. It has reported anticancer activity and is supplied for laboratory research use as a solid with high purity.
- Steroidal saponin natural product isolated from plant roots.
- Reported anticancer activity in the literature.
- High purity suitable for research (99.03%).
- Supplied as a solid in a 10 mg pack size.
- Molecular weight 1,079.23; formula C52H86O23.
- Store at -20°C and protect from light; follow laboratory safety procedures.
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Medchemexpress LLC Nitrofurazone-13C,15N2 | 1217220-85-3 | 99.6% | 5 MG
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Nitrofurazone-13C,15N2, also known as Nitrofural-13C,15N2, is a 13C and 15N labeled derivative of Nitrofurazone. This antibiotic is used topically to treat wounds, burns, ulcers, and skin infections, and in surfactant preparation. It may also affect ecosystem function in marine environments. The stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Supports studies on pharmacokinetic and metabolic profiles of drugs
- Aids in combating various microorganisms
- Applied in the preparation of surfactants
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000340049 COMPLEMENT C5-IN-1 1MG
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eMolecules 871367-14-5 | 7-Bromobenzo[d]oxazol-2(3H)-one | MFCD11111731 | 1g
Ambeed | 7-Bromobenzo[d]oxazol-2(3H)-one | 1g | 600831202 | A150964 | 871367-14-5 | MFCD11111731 | 214.018 | C7H4BrNO2
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