Furans
Medchemexpress LLC Trotabresib | 1706738-98-8 | 99.7% | 383.46 | 50 MG
Trotabresib (CC-90010) is a reversible and orally active BET inhibitor. It is used in the study of advanced solid tumors and inhibits the proliferation of diffuse midline glioma (DMG) cells.
- Reversible and orally active BET inhibitor
- Applied in the study for advanced solid tumors
- Inhibits proliferation of diffuse midline glioma (DMG) cells
- Exhibits stronger antitumor activity against H3K27M mutant DMG cells than DMG wildtype
Medchemexpress LLC DMA-135 hydrochloride | 2237925-62-9 | 98.0% | C16H18ClN7O | 50 MG
DMA-135 hydrochloride is an inhibitor targeting enterovirus 71 (EV71) IRES-dependent translation and replication. It binds to the EV71 SLII domain with moderately high affinity (KD= 520 nM) and shows no significant toxicity in cell-based studies. It induces conformational changes in the RNA structure and stabilizes the ternary complex DMA135-RNA-AUF1, inhibiting the translation and replication of EV71 with an IC50 of 7.54 μM.
- Targets enterovirus 71 (EV71) IRES-dependent translation and replication.
- Binds to the EV71 SLII domain with moderately high affinity.
- Induces conformational changes in RNA structure.
- Stabilizes the ternary complex DMA135-RNA-AUF1.
- Inhibits translation and replication of EV71 with an IC50 of 7.54 μM.
- Demonstrates no significant toxicity in cell-based studies.
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 5 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) used for intravenous applications like postevacuation cholecystography. It is a major bioactive segment of CCK, retaining most of its biological activities. It can promote gallbladder contraction and aids in diagnosing gallbladder and pancreas disorders.
- Increases bile secretion
- Causes gallbladder to contract and relax the sphincter of Oddi, facilitating bile drainage
- Shows inhibitory effect on myocardial fibrosis
- Plays a positive role in fighting inflammation, apoptosis, and collagen deposition
![Medchemexpress LLC 2-Thiazolemethanol, α-[2-[1-(2-amino-5-chloro-4-pyrimidinyl)-2,3-dihydro-1H-indol-6-yl]ethynyl]-α-methyl | 1202764-53-1 | 99.4% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234346.png-250.jpg)
Medchemexpress LLC 2-Thiazolemethanol, α-[2-[1-(2-amino-5-chloro-4-pyrimidinyl)-2,3-dihydro-1H-indol-6-yl]ethynyl]-α-methyl | 1202764-53-1 | 99.4% | 50 MG
B022 is a potent, selective small-molecule inhibitor of NF-κB-inducing kinase (NIK) used for research applications; it contains an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (click chemistry) and is supplied as a solid with reported high purity.
- Potent, selective NIK inhibitor (Ki = 4.2 nM; IC50 ≈ 15.1 nM).
- Contains an alkyne group suitable for click chemistry (CuAAC).
- High reported purity (99.37%).
- Molecular weight 397.88; formula C19H16ClN5OS.
- Soluble in DMSO (250 mg/mL) with recommended formulation options for in vivo use.
- Stable when stored as powder at -20°C or 4°C per manufacturer guidance.
Medchemexpress LLC Nitrofurazone-13C,15N2 | 1217220-85-3 | 99.6% | 5 MG
Nitrofurazone-13C,15N2, also known as Nitrofural-13C,15N2, is a 13C and 15N labeled derivative of Nitrofurazone. This antibiotic is used topically to treat wounds, burns, ulcers, and skin infections, and in surfactant preparation. It may also affect ecosystem function in marine environments. The stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Supports studies on pharmacokinetic and metabolic profiles of drugs
- Aids in combating various microorganisms
- Applied in the preparation of surfactants
Medchemexpress LLC (E)-3',6-disinapoylsucrose | 139891-98-8 | MFCD23379921 | 99.6% | 754.69 g/mol | C34H42O19 | 10 MG
(E)-3',6-disinapoylsucrose is a natural oligosaccharide ester isolated from Polygala tenuifolia and supplied as a high-purity analytical research standard. It exhibits antioxidant and antidepressant activities and is intended for laboratory research use only.
- High purity, 99.6%.
- Molecular weight 754.69 g/mol.
- CAS number 139891-98-8.
- Suitable for analytical, pharmacological, and biochemical research.
- Provided in small, accurately weighed pack sizes for analytical workflows.
- Intended for research use only; not for human consumption.
