Furans
Medchemexpress LLC (3Z)-3-(2-pyridinylmethylene)-1,3-dihydro-2H-indol-2-one | 187325-53-7 | MFCD00435358 | 98.0% | 222.25 | C14H10N2O | 10MG
GSK-3β inhibitor 1 is a potent small-molecule inhibitor of glycogen synthase kinase-3β (compound 3a) with an enzymatic IC50 of 4.19 nM and demonstrated antidiabetic efficacy in streptozotocin-treated obese rat models. The compound is provided as a high-purity research chemical (98.04%) in solid form and as DMSO solutions, and is suitable for in vitro and in vivo research applications.
- Potent enzymatic inhibition (IC50 = 4.19 nM).
- Demonstrated antidiabetic efficacy in animal models.
- High purity suitable for research applications.
- Available as solid and DMSO solution formats.
- Supplied in multiple sizes for scalable experiments.
- Molecular weight 222.25 g·mol⁻¹; formula C14H10N2O.
Apexbio Technology LLC Azimilide 149908-53-2 5mg
Azimilide (CAS 149908-53-2) is a small molecule under investigation for potential anti-arrhythmic activity classified pharmacologically as a class III anti-arrhythmic agent Its mechanism involves inhibition of cardiac delayed rectifier potassium channels specifically targeting both rapid (IKr) and slow (IKs) components By modulating these currents azimilide prolongs cardiac repolarization influencing cardiac rhythm Although not approved for therapeutic use azimilide is currently undergoing clinical evaluation in the United States and serves as a tool compound in arrhythmia-related biomedical research
![Medchemexpress LLC 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide | 304896-28-4 | 99.6% | 434.27 | C23H13Cl2N3O2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211935.png-250.jpg)
Medchemexpress LLC 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide | 304896-28-4 | 99.6% | 434.27 | C23H13Cl2N3O2 | 100 MG
AGK2 is a selective small-molecule inhibitor of SIRT2 used to probe sirtuin biology and apoptosis-related pathways in biochemical and cellular studies. It is cell permeable and reported to inhibit SIRT2 with an IC50 of 3.5 μM, while showing weaker activity against SIRT1 and SIRT3.
Medchemexpress LLC HY-101090 5mg Medchemexpress, KYA1797K CAS:1956356-56-1 Purity:>98%
Medchemexpress, HY-101090 5mg KYA1797K CAS:1956356-56-1 KYA1797K is a potent and selective Wnt/β-catenin inhibitor with an IC 50 of 0.75 µM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1314118-94-9 | MK2-IN-1 hydrochloride | MFCD29472226 | 25mg
ChemScene | (S)-tert-Butyl (3-hydroxy-11-diphenylpropan-2-yl)carbamate | 100mg | 694122996 | CS-W013937 | 155836-47-8 | MFCD01863566 | 327.424 | C20H25NO3
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Medchemexpress LLC Dantrolene | 7261-97-4 | MFCD00867709 | 98.4% | 314.26 | C14H10N4O5 | 5MG
Dantrolene is a research-grade skeletal muscle relaxant and ryanodine receptor (RyR) calcium channel modulator supplied as a high-purity solid or prepared solution for in vitro and analytical applications. The material is provided in small pack sizes suitable for biochemical assays, cellular studies, and method development; follow the supplier datasheet for handling, storage, and safety information.
- High reported purity suitable for research assays.
- Supplied in small quantities for low-usage experiments.
- Available as solid or ready-to-use DMSO solution.
- Suitable for biochemical and cellular RyR/calcium studies.
- Includes datasheet and documentation for traceability.
- Store according to supplier recommendations to maintain stability.
eMolecules 328968-36-1 | Medchem Express | C646 | 10mg | 446263588 | HY-13823 | MFCD06125650 | 445.431 | C24H19N3O6
Medchem Express | Sofiniclin | 1mg | 415687348 | HY-14824 | 799279-80-4 | MFCD19443714 | 244.120 | C10H11Cl2N3
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Apexbio Technology LLC DANTROLENE-25MG
Dantrolene (CAS No 7261-97-4) is a hydantoin derivative primarily used in the research category of muscle relaxants originating from its unique ability to interfere with excitation-contraction coupling in skeletal muscle Its mechanism of action involves blocking the ryanodine receptor (RyR1) calcium channels in the sarcoplasmic reticulum reducing calcium release and subsequent muscle contraction In vitro it exhibits activity in the nanomolar to low micromolar range Dantrolene is frequently applied in studies utilizing cell models to investigate calcium dynamics and neuroprotection as well as in animal studies exploring its potential in treating conditions such as malignant hyperthermia and muscular dystrophies It is also used in drug screening for therapeutic agents targeting calcium-related disorders Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC DANTROLENE-100MG
Dantrolene (CAS No 7261-97-4) is a hydantoin derivative primarily used in the research category of muscle relaxants originating from its unique ability to interfere with excitation-contraction coupling in skeletal muscle Its mechanism of action involves blocking the ryanodine receptor (RyR1) calcium channels in the sarcoplasmic reticulum reducing calcium release and subsequent muscle contraction In vitro it exhibits activity in the nanomolar to low micromolar range Dantrolene is frequently applied in studies utilizing cell models to investigate calcium dynamics and neuroprotection as well as in animal studies exploring its potential in treating conditions such as malignant hyperthermia and muscular dystrophies It is also used in drug screening for therapeutic agents targeting calcium-related disorders Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC DANTROLENE-10MG
Dantrolene (CAS No 7261-97-4) is a hydantoin derivative primarily used in the research category of muscle relaxants originating from its unique ability to interfere with excitation-contraction coupling in skeletal muscle Its mechanism of action involves blocking the ryanodine receptor (RyR1) calcium channels in the sarcoplasmic reticulum reducing calcium release and subsequent muscle contraction In vitro it exhibits activity in the nanomolar to low micromolar range Dantrolene is frequently applied in studies utilizing cell models to investigate calcium dynamics and neuroprotection as well as in animal studies exploring its potential in treating conditions such as malignant hyperthermia and muscular dystrophies It is also used in drug screening for therapeutic agents targeting calcium-related disorders Experimental concentrations typically depend on the specific research design
eMolecules 724711-21-1 | Medchem Express | MK2-IN-3 | 5mg | 599150665 | HY-131249 | MFCD16293712 | 340.386 | C21H16N4O
Medchem Express | MK2-IN-3 | 5mg | 599150665 | HY-131249 | 724711-21-1 | MFCD16293712 | 340.386 | C21H16N4O