Indoles and derivatives

Aromatic bicyclic organic compounds that consists of a benzene ring fused to a pyrrole ring with formula: C₈H₇N.

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2,236 – 2,250 of 5,979 results

2,236

eMolecules 860624-90-4 | 5-Bromo-1H-indole-7-carboxylic acid | Ambeed | MFCD11845481 | 240.056 | C9H6BrNO2 | 97.000 | OC(=O)c1cc(Br)cc2cc[nH]c12 | 1g | 525163768

5-Bromo-1H-indole-7-carboxylic acid | Ambeed | 860624-90-4 | MFCD11845481 | 240.056 | C9H6BrNO2 | 97.000 | OC(=O)c1cc(Br)cc2cc[nH]c12 | 1g | 525163768

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2,237

Aobchem 5-Chloro-1H-indole | ≥95% | CAS 17422-32-1 | C8H6ClN | 25g

5-Chloro-1H-indole | ≥95% | CAS 17422-32-1 | C8H6ClN | 25g

Pricing & Availability

2,238

Aobchem 4-Bromo-7-isopropyl-1H-indole | 97% | CAS 1219741-52-2 | C11H12BrN | 500mg

4-Bromo-7-isopropyl-1H-indole | 97% | CAS 1219741-52-2 | C11H12BrN | 500mg

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2,239

Aobchem Methyl 1H-indole-5-carboxylate | ≥97% | CAS 1011-65-0 | C10H9NO2 | 10g

Methyl 1H-indole-5-carboxylate | ≥97% | CAS 1011-65-0 | C10H9NO2 | 10g

Pricing & Availability

2,240

eMolecules 3764-94-1 | 5-Chlorotryptamine hydrochloride | Chem-Impex | MFCD00130168 | 194.660 | C10H11ClN2 | 95.000 | NCCc1c[nH]c2ccc(Cl)cc12 | 1g | 112755555

5-Chlorotryptamine hydrochloride | Chem-Impex | 3764-94-1 | MFCD00130168 | 194.660 | C10H11ClN2 | 95.000 | NCCc1c[nH]c2ccc(Cl)cc12 | 1g | 112755555

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2,241

Medchemexpress LLC Nevadensin | 10176-66-6 | 344.32 | 5 MG

Nevadensin (Lysionotin) is a natural flavonoid that acts as a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM, showing more selectivity for hCE1 than hCE2 (IC50 of 132.8 μM). It can induce apoptosis and DNA damage in cancer cells. This compound exhibits a range of pharmacological effects, including anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant, and anti-microbial activities.

Natural flavonoid
Selective human carboxylesterase 1 (hCE1) inhibitor
Induces apoptosis and DNA damage in cancer cells
Possesses anti-inflammatory activity
Exhibits anti-tumour effects
Has anti-hypertensive properties
Demonstrates anti-tubercular activity
Acts as an antitussive
Functions as an antioxidant
Shows anti-microbial activities

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2,242

Medchemexpress LLC Erenapurstat | 136164-66-4 | 99.67% | 378.46 | 50 MG

Erenapurstat (E3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. It impairs tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer, showing anticancer activities.

Targets Ape-1 and Ref-1
Inhibits growth of HUVECs, PCECs, and EPCs
Reduces VEGF expression in pancreatic cancer cells
Inhibits differentiation of BM-MSCs into CD31+ endothelial lineage cells
Decreases cell viability in H1975 cells
Inhibits growth and migration of pancreatic cancer cells
Enhances intracellular ROS level and inhibits CD44 expression in PANC1 cells
Neuroprotective against cisplatin-induced alterations
Attenuates liver injury in rats

Pricing & Availability

2,243

eMolecules 850623-66-4 | Potassium trifluoro(4-isobutylphenyl)borate | Ambeed | MFCD04115761 | 240.120 | C10H13BF3K | 98.000 | [K+].CC(C)Cc1ccc(cc1)[B-](F)(F)F | 1g | 586036590

Potassium trifluoro(4-isobutylphenyl)borate | Ambeed | 850623-66-4 | MFCD04115761 | 240.120 | C10H13BF3K | 98.000 | [K+].CC(C)Cc1ccc(cc1)[B-](F)(F)F | 1g | 586036590

Pricing & Availability

2,244

Sigma Aldrich Fine Chemicals Biosciences 5-Benzyloxytryptamine hydrochloride 98% | 52055-23-9 | MFCD00012685 | 1G

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2,245

Medchemexpress LLC Sisunatovir hydrochloride | 1903763-83-6 | 98.6% | 482.90 g/mol | C23H23ClF4N4O | 5MG

Sisunatovir hydrochloride is the hydrochloride salt of sisunatovir (RV521), an orally active respiratory syncytial virus (RSV) fusion protein inhibitor supplied as a research-grade solid for in vitro and in vivo antiviral studies. It has defined molecular properties and high analytical purity appropriate for pharmacology and virology research.

Potent RSV fusion inhibitor for antiviral research.
Provided as a hydrochloride salt in solid powder form.
High purity suitable for in vitro and in vivo studies.
Well characterized molecular weight and chemical formula.
Available in small research-scale quantities for assay use.

Pricing & Availability

2,246

eMolecules 857969-66-5 | 5-Bromothiazolo[5,4-b]pyridine | ChemScene | MFCD17014628 | 215.070 | C6H3BrN2S | 97.000 | Brc1ccc2ncsc2n1 | 100mg | 632303341

5-Bromothiazolo[5,4-b]pyridine | ChemScene | 857969-66-5 | MFCD17014628 | 215.070 | C6H3BrN2S | 97.000 | Brc1ccc2ncsc2n1 | 100mg | 632303341

Pricing & Availability

2,247

eMolecules 1227374-66-4 | Ambeed | (11bR)-N-(26-Di(naphthalen-1-yl)-4-oxido-89101112131415-octahydrodinaphtho[21-d12-f][132]dioxaphosphepin-4-yl)-111-trifluoromethanesulfonamide | 50mg | 633658969 | A1006129 | 739.75 | C41H33F3NO5PS

Ambeed | 1-(Chloro(pyrrolidin-1-yl)methylene)pyrrolidin-1-ium hexafluorophosphate(V) | 5g | 600846473 | A723618 | 135540-11-3 | MFCD00191333 | 332.660 | C9H16ClF6N2P

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2,248

Medchemexpress LLC Farudodstat (ASLAN003) | 1035688-66-4 | 99.7% | 100 MG

Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for the human DHODH enzyme. Its mechanism of action involves inhibiting protein synthesis by activating AP-1 transcription factors. This compound induces apoptosis and significantly prolongs survival in acute myeloid leukemia (AML) xenograft mice.

Exhibits antiproliferative activity against various human cell lines.
Inhibits leukemic cell proliferation in vitro.
Increases cleaved caspase 8.
Decreases viability and induces differentiation in primary acute myeloid leukemia blasts and myelodysplastic syndrome samples.
Inhibits protein synthesis by reducing O-propargyl-puromycin (OPP) incorporation and downregulating EIF4B and RPL6 proteins.
Substantially reduces the number and size of disseminated tumors in vivo.
Available as a white to off-white solid.

Pricing & Availability

2,249

Medchemexpress LLC Maralixibat chloride | 228113-66-4 | 99.6% | 710.41 | 5 MG

Maralixibat chloride (SHP625) is an orally active ileal bile acid transporter (IBAT) inhibitor. It is used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. It reduces elevations in sBA levels, improves liver function, and reduces liver tissue damage in cholestasis models.

Orally active ileal bile acid transporter (IBAT) inhibitor
Suitable for research into rare cholestatic liver diseases such as Alagille syndrome, progressive familial intrahepatic cholestasis, and biliary atresia
Reduces elevations in sBA levels
Improves liver function
Reduces liver tissue damage in cholestasis models

Pricing & Availability

2,250

eMolecules 191403-66-4 | (S)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE | AstaTech | MFCD00672872 | 191.230 | C11H13NO2 | 97.000 | O[C@@H]1CN(Cc2ccccc2)C(=O)C1 | 0.25g | 200610938

(S)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE | AstaTech | 191403-66-4 | MFCD00672872 | 191.230 | C11H13NO2 | 97.000 | O[C@@H]1CN(Cc2ccccc2)C(=O)C1 | 0.25g | 200610938

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Indoles and derivatives

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Medchemexpress LLC Nevadensin | 10176-66-6 | 344.32 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Erenapurstat | 136164-66-4 | 99.67% | 378.46 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sisunatovir hydrochloride | 1903763-83-6 | 98.6% | 482.90 g/mol | C23H23ClF4N4O | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Farudodstat (ASLAN003) | 1035688-66-4 | 99.7% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Maralixibat chloride | 228113-66-4 | 99.6% | 710.41 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nevadensin | 10176-66-6 | 344.32 | 5 MG

Medchemexpress LLC Erenapurstat | 136164-66-4 | 99.67% | 378.46 | 50 MG

Medchemexpress LLC Sisunatovir hydrochloride | 1903763-83-6 | 98.6% | 482.90 g/mol | C23H23ClF4N4O | 5MG

Medchemexpress LLC Farudodstat (ASLAN003) | 1035688-66-4 | 99.7% | 100 MG

Medchemexpress LLC Maralixibat chloride | 228113-66-4 | 99.6% | 710.41 | 5 MG