Lactams
Medchemexpress LLC Thalidomide-5-O-C12-NH2 hydrochloride | 99.9% | 494.02 g/mol | C25H36ClN3O5 | 10 MG
Thalidomide-5-O-C12-NH2 hydrochloride is a thalidomide-derived cereblon ligand supplied as the hydrochloride salt for research applications. It is intended for use as an E3 ligase recruiter in PROTAC design and biochemical assays that engage CRBN. For research use only.
- High purity 99.9%.
- Molecular formula C25H36ClN3O5.
- Molecular weight 494.02 g/mol.
- Supplied in small milligram quantities, including 10 mg.
- Suitable for ligand conjugation and targeted protein degradation studies.
- Store protected from light; short-term at -20°C, long-term at -80°C in solvent.
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | 98.0% | 586.03 | C25H36ClN5O9 | 5 MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a PEG4-C2 spacer. Supplied as the hydrochloride salt in solid form and reported at high purity, the compound is intended as a building block for PROTAC design and other CRBN-recruiting chemical biology applications.
- E3 ligase ligand-linker conjugate for PROTAC construction.
- Includes a thalidomide-based cereblon ligand to recruit CRBN proteins.
- PEG4-C2 linker with terminal amine for facile conjugation.
- Hydrochloride salt form to aid handling and solubility.
- High purity suitable for synthetic and research workflows.
Medchemexpress LLC 14-3-3 epsilon protein (human), GST-tagged | >95.0% | 5 UG
Recombinant human 14-3-3 epsilon protein fused to an N-terminal GST tag, expressed in Escherichia coli and supplied at high purity for research use. It is suitable for immunoassays, binding studies, and functional assays investigating 14-3-3-mediated signaling and inflammatory responses.
- Source species: human.
- Expression system: Escherichia coli.
- Tag: N-terminal GST.
- Purity: >95.0% by reducing SDS-PAGE.
- Molecular weight: approximately 55.0-58.0 kDa.
- Available size: 5 μg, suitable for assay use.
- Storage: store at -20 °C; after reconstitution stable at 4 °C for 1 week; aliquot and freeze at -80 °C for long term.
- Reported activity: ED50 = 0.3162 μg/mL in antibody-binding assay.
Medchemexpress LLC Epsilon-momfluorothrin | 1065124-65-3 | 99.8% | 385.35 | 1 ML
Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide that activates the constitutive androstane receptor (CAR) and induces hepatocellular tumors in rats. It is for research use only and not sold to patients.
- Type I synthetic pyrethroid insecticide
- Activates constitutive androstane receptor (CAR)
- Induces hepatocellular tumors in rats
Medchemexpress LLC CD23/Fc epsilon RII 50ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
Medchemexpress LLC Fc epsilon RIA/FCER1 10ug
Recombinant human Fc epsilon RIA (FCER1A) is the extracellular alpha chain of the high-affinity IgE receptor supplied as a His-SUMO-tagged recombinant protein. The lyophilized protein is intended for use in binding studies, ELISA, and other immunological or biochemical assays requiring the human FCER1A ectodomain.
- His-SUMO tagged protein for affinity purification and detection.
- Expressed in E. coli and supplied lyophilized for enhanced stability.
- Purity >95% as determined by reducing SDS-PAGE.
- Formulated with trehalose and EDTA for increased storage stability.
- Suitable for ELISA and binding assays; functional activity characterized.
- Recommended reconstitution at or above 100 μg/mL for optimal performance.
Medchemexpress LLC CD3 epsilon Rat HE 5ug | 5ug
CD3 epsilon Protein a vital component of the TCR-CD3 complex on T-lymphocytes is pivotal for adaptive immune responses CD3E is crucial for proper T-cell development and contributes to TCR-CD3 complex internalization and down-regulation[1] CD3 epsilon Protein Rat (HEK293 Fc) is the recombinant rat-derived CD3 epsilon protein expressed by HEK293 with C-hFc labeled tag
Alkali Scientific Aztreonam, 1 G
Aztreonam (1 g) is a monobactam antibiotic used in laboratory-grade antibacterial research. It is highly effective against Gram-negative bacteria and operates by inhibiting cell wall synthesis. This antibiotic is widely utilized in research to study the efficacy of antibacterial agents, particularly in drug resistance and antibacterial therapy studies. Aztreonam's mechanism of action makes it a crucial reagent in research on antibiotic resistance, pharmacokinetics, and pharmacodynamics. It is also commonly used in microbiological testing to analyze bacterial responses and resistance patterns in clinical and laboratory settings.
eMolecules 676560-15-9 | Ethyl 4-((tert-butyldimethylsilyl)oxy)cyclohexanecarboxylate | MFCD24038913 | 1g
Ambeed | Ethyl 4-((tert-butyldimethylsilyl)oxy)cyclohexanecarboxylate | 1g | 490561494 | A433149 | 676560-15-9 | MFCD24038913 | 286.487 | C15H30O3Si
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 699020-11-6 | BENZYL 5-(TERT-BUTYLDIMETHYLSILYLOXY)PENTYLCARBAMATE | MFCD23378614 | 1g
AstaTech | BENZYL 5-(TERT-BUTYLDIMETHYLSILYLOXY)PENTYLCARBAMATE | 1g | 402180213 | 21198 | 95.000 | 699020-11-6 | MFCD23378614 | 351.562 | C19H33NO3Si
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 28562-58-5 | 4-Benzoyloxy-2-azetidinone | Combi-Blocks | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 5g | 267200513
4-Benzoyloxy-2-azetidinone | Combi-Blocks | 28562-58-5 | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 5g | 267200513