Lactams
Medchemexpress LLC Thalidomide-4-F,5-Br | 2740657-28-5 | 99.4% | 355.12 g·mol⁻¹ | C13H8BrFN2O4 | 50 MG
Thalidomide-4-F,5-Br is a thalidomide analogue used as a cereblon (CRBN) E3 ligase ligand in biochemical research. It is provided as a purified powder for use in degradation studies, PROTAC design, and related cell biology and biochemical assays.
- Acts as a cereblon E3 ligase ligand for targeted protein ubiquitination and degradation.
- Suitable for PROTAC synthesis and biochemical assay development.
- Supplied as a powder form for convenient handling and storage.
- High purity (~99%) suitable for research applications.
- Molecular weight approximately 355.12 g·mol⁻¹.
- Available in multiple small package sizes for laboratory use.
Medchemexpress LLC Thalidomide-1-Me,4-OH | 2244568-06-5 | >98.0% | 288.26 | C14H12N2O5 | 25 MG
Thalidomide-1-Me,4-OH is a thalidomide analogue with a 1-methyl and 4-hydroxyl substitution that functions as an E3 ubiquitin ligase ligand. It is used in biochemical research to recruit E3 ligases (Cereblon-related activity) for targeted protein degradation studies.
- Acts as an E3 ligase ligand suitable for cereblon-mediated recruitment.
- Contains 1-methyl and 4-hydroxyl substitutions on the thalidomide scaffold.
- Molecular formula C14H12N2O5, molecular weight 288.26.
- Purity greater than 98%.
- Recommended storage: powder at -20°C (long-term) or 4°C (short-term); in solvent at -80°C for extended storage.
- Supplied in small research quantities, e.g., 25 MG, for biochemical assays.
Medchemexpress LLC Thalidomide-4-Br | 2093536-12-8 | MFCD31730866 | 99.7% | 337.13 g·mol⁻¹ | C13H9BrN2O4 | 10 MG
Thalidomide-4-Br is a brominated derivative of thalidomide that acts as a small-molecule bromodomain probe. It is provided as a high-purity solid for in vitro and preclinical research in inflammation, oncology, and neurology.
- Bromodomain-containing small molecule probe.
- Suitable for inflammation, tumor, and neurology research.
- High purity: 99.7%.
- Molecular formula C13H9BrN2O4; molecular weight 337.13 g·mol⁻¹.
- Available in multiple pack sizes including 10 mg.
- Powder storage: -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Tetrazine tagged thalidomide | 2087490-42-2 | 98.6% | 571.58 g/mol | C29H29N7O6 | 1 ML
Tz-Thalidomide is a tetrazine-tagged thalidomide derivative supplied for research use as an E3 ligase ligand and chemical biology probe. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities for synthesis and assay use, and is intended for applications in targeted protein degradation and PROTAC development.
- Tetrazine functional group enables rapid inverse electron demand Diels-Alder (iEDDA) click reactions.
- Supplied as a 10 mM solution in DMSO for immediate experimental use.
- High purity (98.6%) appropriate for biological testing and chemical biology workflows.
- Molecular weight 571.58 and formula C29H29N7O6 for accurate dosing and formulation.
- Available in solid amounts for synthetic chemistry and scale-up experiments.
Sigma Aldrich Fine Chemicals Biosciences (+)-Thalidomide >=98% (HPLC), powder | 2614-06-4 | MFCD00210220 | 10MG
(+)-Thalidomide >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 258.23 | 2614-06-4 | MFCD00210220 | 10MG
