Lactams
Medchemexpress LLC Thalidomide-5-CH2-NH2 hydrochloride | 1010100-22-7 | MFCD32666042 | 98.6% | 323.73 g/mol | C14H14ClN3O4 | 25 MG
Thalidomide-5-CH2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt. It provides a reactive primary amine at the 5-position for linker attachment and is used as an E3 ligase recruiting moiety in PROTAC design and related chemical biology research. Suitable for medicinal chemistry and linker-conjugation workflows.
Medchemexpress LLC Thalidomide-iodo | 2509137-01-1 | MFCD31735039 | >98.0% | 384.13 g/mol | C13H9IN2O4 | 1 G
Thalidomide-iodo is an iodinated thalidomide derivative that acts as an E3 ligase activator and ligand for cereblon, used in targeted protein degradation and PROTAC research. The iodine substituent enables further derivatization through cross-coupling or substitution, supporting synthesis of linker conjugates and chemical probes. Supplied as a high-purity research chemical.
Apexbio Technology LLC Thalidomide 50-35-1 10mM (in 1mL DMSO)
Thalidomide (CAS 50-35-1) is a small-molecule inhibitor targeting the CRBN-DDB1-Cul4A E3 ubiquitin ligase complex It is designed to modulate ubiquitination pathways thereby regulating protein degradation cellular proliferation and immune signaling Thalidomide exerts its biological activity primarily through inhibition of the CRBN-DDB1-Cul4A complex In cell-based studies thalidomide demonstrates inhibitory activity with reported IC50 values ranging from approximately 1 M to 100 M depending on the assay and cell line Based on these pharmacological properties thalidomide holds research potential in the fields of immune regulation angiogenesis inhibition and cancer biology particularly in studies of hematological malignancies such as multiple myeloma
Cayman Chemical AzIdo-ThalIdomIde 25mg
A PROTAC building block; contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry; has been used in the synthesis of a SirReal-based PROTAC for the degradation of Sirt2 in cells
Medchemexpress LLC CD3 epsilon Human 500ug
Recombinant human CD3 epsilon protein produced in HEK293 mammalian cells and supplied as a lyophilized preparation with a C-terminal 6xHis tag, intended for research use in studies of T-cell receptor signaling, binding assays, and related immunological applications. Lot-specific COA provides detailed formulation and buffer information.
- Produced in HEK293 mammalian expression system.
- C-terminal 6xHis tag for detection and purification.
- Lyophilized powder formulation for convenient storage and handling.
- Approximate molecular weight 18-21 kDa by SDS-PAGE.
- Stable at -20 °C for long-term storage; reconstituted stability at 4 °C for one week.
- Lot-specific COA and datasheet available for quality and formulation details.
Alkali Scientific Aztreonam, 25 Mg
Aztreonam is a monobactam antibiotic used in antibacterial research. This 25mg laboratory-grade sample is used for studying bacterial resistance mechanisms and testing the efficacy of monobactam antibiotics in inhibiting bacterial growth. Aztreonam is particularly effective against Gram-negative bacteria, making it an important compound for research on infectious diseases caused by these organisms. It is also utilized in laboratory studies to explore the antibacterial properties of monobactams in combination therapies. This 25mg quantity is sufficient for several antimicrobial studies and assay testing in microbiological research.
eMolecules 699020-11-6 | BENZYL 5-(TERT-BUTYLDIMETHYLSILYLOXY)PENTYLCARBAMATE | MFCD23378614 | 1g
AstaTech | BENZYL 5-(TERT-BUTYLDIMETHYLSILYLOXY)PENTYLCARBAMATE | 1g | 402180213 | 21198 | 95.000 | 699020-11-6 | MFCD23378614 | 351.562 | C19H33NO3Si
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eMolecules Building Block Tool<|a>
eMolecules 28562-58-5 | 4-Benzoyloxy-2-azetidinone | Combi-Blocks | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 1g | 267200512
4-Benzoyloxy-2-azetidinone | Combi-Blocks | 28562-58-5 | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 1g | 267200512
eMolecules 17557-84-5 | 3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
eMolecules 17557-84-5 | 3-Azetidinone HCl | Ambeed | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 570568402
3-Azetidinone HCl | Ambeed | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 570568402