Lactams
Medchemexpress LLC Thalidomide-4-F,5-Br | 2740657-28-5 | 99.4% | 355.12 g·mol⁻¹ | C13H8BrFN2O4 | 50 MG
Thalidomide-4-F,5-Br is a thalidomide analogue used as a cereblon (CRBN) E3 ligase ligand in biochemical research. It is provided as a purified powder for use in degradation studies, PROTAC design, and related cell biology and biochemical assays.
- Acts as a cereblon E3 ligase ligand for targeted protein ubiquitination and degradation.
- Suitable for PROTAC synthesis and biochemical assay development.
- Supplied as a powder form for convenient handling and storage.
- High purity (~99%) suitable for research applications.
- Molecular weight approximately 355.12 g·mol⁻¹.
- Available in multiple small package sizes for laboratory use.
Medchemexpress LLC Thalidomide-1-Me,4-OH | 2244568-06-5 | >98.0% | 288.26 | C14H12N2O5 | 25 MG
Thalidomide-1-Me,4-OH is a thalidomide analogue with a 1-methyl and 4-hydroxyl substitution that functions as an E3 ubiquitin ligase ligand. It is used in biochemical research to recruit E3 ligases (Cereblon-related activity) for targeted protein degradation studies.
- Acts as an E3 ligase ligand suitable for cereblon-mediated recruitment.
- Contains 1-methyl and 4-hydroxyl substitutions on the thalidomide scaffold.
- Molecular formula C14H12N2O5, molecular weight 288.26.
- Purity greater than 98%.
- Recommended storage: powder at -20°C (long-term) or 4°C (short-term); in solvent at -80°C for extended storage.
- Supplied in small research quantities, e.g., 25 MG, for biochemical assays.
Medchemexpress LLC Thalidomide-5-O-C5-NH2 hydrochloride | 2761385-94-6 | 395.84 | C18H22ClN3O5 | 10 MG
Thalidomide-5-O-C5-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand provided as the hydrochloride salt for use in chemical biology research. It is designed for incorporation into ligand-linker conjugates and PROTAC constructs to recruit CRBN and enable targeted protein degradation. The material is supplied as a research-grade powder with recommended cold, light-protected storage conditions.
Medchemexpress LLC Thalidomide-5-O-C12-NH2 hydrochloride | 99.9% | 494.02 g/mol | C25H36ClN3O5 | 10 MG
Thalidomide-5-O-C12-NH2 hydrochloride is a thalidomide-derived cereblon ligand supplied as the hydrochloride salt for research applications. It is intended for use as an E3 ligase recruiter in PROTAC design and biochemical assays that engage CRBN. For research use only.
- High purity 99.9%.
- Molecular formula C25H36ClN3O5.
- Molecular weight 494.02 g/mol.
- Supplied in small milligram quantities, including 10 mg.
- Suitable for ligand conjugation and targeted protein degradation studies.
- Store protected from light; short-term at -20°C, long-term at -80°C in solvent.
Medchemexpress LLC Thalidomide-NH-C10-NH2 hydrochloride | 2460022-53-9 | 464.99 | C23H33ClN4O4 | 10 MG
Thalidomide-NH-C10-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt in solid form for research use. It is intended for incorporation into PROTACs and other E3 ligase recruiting conjugates for chemical biology and medicinal chemistry studies.
- Thalidomide-derived cereblon ligand for E3 ligase recruitment.
- Suitable for PROTAC construction and linker conjugation.
- Provided as a solid hydrochloride salt for stability and handling.
- Available in small milligram packages appropriate for synthesis and assays.
- Store sealed, away from moisture and light; follow supplier storage guidance.
Medchemexpress LLC Thalidomide-o-amido-c3-peg3-c1-nh2 trifluoroacetate | 1799711-29-7 | MFCD32878273 | 99.1% | C27H35F3N4O11 | 10MG
Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that couples a thalidomide-derived cereblon ligand to a three-unit polyethylene glycol linker, designed for PROTAC synthesis and related chemical biology research. The compound is supplied as an off-white to light yellow oil, with molecular formula C27H35F3N4O11, molecular weight 648.58 g·mol⁻¹, and high purity suitable for research.
- Contains a thalidomide-derived cereblon ligand for E3 ligase recruitment.
- Includes a three-unit polyethylene glycol linker to enhance flexibility and solubility.
- Designed for PROTAC design and targeted protein degradation studies.
- High purity (99.1%) for consistent experimental results.
- Characterized molecular properties facilitate reproducible use in research.
- Available in small packaging sizes suitable for laboratory studies.
Medchemexpress LLC Thalidomide-4-O-C10-NH2 hydrochloride | 00-00-0 | 95.6% | C23H32ClN3O5 | 10MG
Thalidomide-4-O-C10-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand formulated as a hydrochloride salt for use in PROTAC design and related biochemical research. Supplied as a solid with reported high purity, it is intended for small-scale laboratory studies and compound linking applications.
- Hydrochloride salt form for improved stability
- High purity suitable for research applications
- Molecular formula C23H32ClN3O5 and molecular weight 465.97
- Available in small packaging sizes for synthesis and screening
- Solid form for convenient handling and storage
Medchemexpress LLC Thalidomide-5-O-C6-NH2 hydrochloride | 2761398-05-2 | 409.86 | C19H24ClN3O5 | 10 MG
Thalidomide-5-O-C6-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC development and chemical biology research. The compound contains a six-carbon linker terminating in a primary amine and is supplied as the hydrochloride salt to aid handling and stability for research applications.
- Used as a cereblon ligand to recruit CRBN in PROTAC and degrader design.
- Contains a C6 linker with a terminal amine for conjugation to linkers or target ligands.
- Provided as a hydrochloride salt for improved handling and solubility.
- Solid form suitable for storage under recommended conditions.
- Intended for research use; consult vendor documentation or COA for purity and analytical data.
Medchemexpress LLC CD3 epsilon Canine 10ug | 10ug
The CD3 protein on lymphocytes is a component of the TCR-CD3 complex and is critical for adaptive immune responses When APC is activated TCR signals transmitted by CD3D CD3E CD3G and CD3Z initiate pathways through ITAM CD3 epsilon Protein Canine (HEK293 Fc) is the recombinant canine-derived CD3 epsilon protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC CD3 epsilon Canine 100ug | 100ug
The CD3 protein on lymphocytes is a component of the TCR-CD3 complex and is critical for adaptive immune responses When APC is activated TCR signals transmitted by CD3D CD3E CD3G and CD3Z initiate pathways through ITAM CD3 epsilon Protein Canine (HEK293 Fc) is the recombinant canine-derived CD3 epsilon protein expressed by HEK293 with C-hFc labeled tag
Selleck Chemical LLC Tazobactam S3077-500mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect