Lactams
Medchemexpress LLC Thalidomide-NH-C10-COOH | 2428400-33-1 | 97.5% | 250 MG
Thalidomide-NH-C10-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide based CRBN ligand and a linker used in PROTAC technology. With a molecular weight of 457.52 and formula C24H31N3O6, this compound appears as a light yellow to yellow solid. It is intended for research use only.
- Targets cereblon.
- Recommended storage for powder is -20°C for 3 years or 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Part of PROTAC technology.
Medchemexpress LLC Thalidomide-4-O-C12-NH2 hydrochloride | 95.6% | 494.02 | C25H36ClN3O5 | 10 MG
Thalidomide-4-O-C12-NH2 hydrochloride is a thalidomide-derived cereblon ligand provided as the hydrochloride salt for use in chemical biology and medicinal chemistry applications. It functions as a CRBN E3 ligase recruiter for targeted protein degradation and is intended for use in PROTAC and ligand-linker conjugation studies. Store protected from light at recommended temperatures.
Medchemexpress LLC Deoxy-thalidomide-5-iodine | 2291364-01-5 | MFCD32853043 | 98.0% | 370.14 g/mol | C13H11IN2O3 | 250 MG
Deoxy-thalidomide-5-iodine is a thalidomide analog used as a cereblon-binding ligand in targeted protein degradation and PROTAC research. It is provided as a characterized small-molecule building block suitable for conjugation in bifunctional degrader synthesis and related chemical biology applications.
- Used as cereblon-binding ligand for PROTAC development.
- High reported purity: 98.0% (NMR).
- Molecular weight 370.14 g/mol and formula C13H11IN2O3.
- Solid; store at 4°C and protect from light.
- Available in multiple package sizes, including 250 mg.
Medchemexpress LLC Thalidomide-C2-amido-C2-COOH | 2353496-84-9 | 98.5% | C19H20N4O7 | 10MG
Thalidomide-C2-amido-C2-COOH is a thalidomide-derived cereblon (CRBN) ligand-linker conjugate for research use. Supplied as a powder, it is intended as a building block for design and synthesis of PROTAC degraders and other molecules that recruit the CRBN E3 ubiquitin ligase.
- Incorporates a cereblon-binding thalidomide moiety for E3 ligase recruitment.
- Contains a short C2-amido-C2-COOH linker for conjugation to target ligands.
- High purity (98.5%) suitable for synthetic and analytical work.
- Molecular formula and weight provided to support design calculations.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Powder form allows long-term frozen storage for stability.
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | >98.0% | 586.03 | 25 MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It integrates a thalidomide-based cereblon ligand with a linker, making it suitable for applications in PROTAC technology. This compound is intended for research purposes only and is not for sale to patients.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- Utilizes a linker for PROTAC technology applications
- Suitable for research use
TARGETMOL CHEMICALS INC S-THALIDOMIDE 5MG
Also available in 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. (S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory anti-inflammatory anticancer anti-angiogenic and pro-apoptotic activities and is used in the study of leprosy erythema nodosum and myeloma. purity: 99%
TARGETMOL CHEMICALS INC ACY-957 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s 7 nM 18 nM and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9. purity: 98%
Apexbio Technology LLC Laurocapram 59227-89-3 1g
Laurocapram is an amphiphilic compound primarily applied as a percutaneous absorption enhancer Laurocapram exerts its biological activity by temporarily altering the lipid architecture within the stratum corneum thereby lowering barrier resistance and increasing skin and mucosal permeability to both hydrophilic and lipophilic substances Based on these pharmacological properties Laurocapram holds research potential in the investigation of transdermal drug delivery mechanisms evaluation of pharmacokinetic profiles and the development of topical therapeutic agents and delivery formulations
Medchemexpress LLC Laurocapram | 59227-89-3 | 281.48 | 1 ML
Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, improving their local or systemic efficacy. It enhances the skin permeability of various hydrophilic and lipophilic compounds. This product is provided as a 10 mM solution in 1 mL, suitable for research applications.
- Increases permeability of compounds through skin and mucous membranes.
- Improves local or systemic efficacy of compounds.
- Enhances skin permeability for both hydrophilic and lipophilic compounds.
- Synergizes with β-lactam antibiotics to improve antibacterial activity against S. aureus.
- Exhibits anti-infectious activity in MRSA-induced mouse pneumonia models.
- Ameliorates infection wounds in MRSA-administrated mouse skin infection models.
Sigma Aldrich Fine Chemicals Biosciences Strychnine | 57-24-9 | MFCD00005941 | 5G
Strychnine | Mol Wt: 334.41 | 57-24-9 | MFCD00005941 | 5G
Aobchem 1-(Diphenylmethyl)-2-fluorobenzene | 95% | CAS 436-11-3 | C19H15F | 1g
1-(Diphenylmethyl)-2-fluorobenzene | 95% | CAS 436-11-3 | C19H15F | 1g
Aobchem 1-(Diphenylmethyl)-2-fluorobenzene | 95% | CAS 436-11-3 | C19H15F | 5g
1-(Diphenylmethyl)-2-fluorobenzene | 95% | CAS 436-11-3 | C19H15F | 5g