Lactams
Apexbio Technology LLC Brucine 10mM (in 1mL DMSO)
N1490 is a small-molecule inhibitor designed for biomedical research It exerts its effects by selectively targeting and modulating specific intracellular signaling pathways implicated in disease progression N1490 has been explored in cellular assays for its ability to interfere with relevant molecular interactions resulting in altered downstream signaling events This compound serves as a valuable tool for investigating cellular mechanisms regulated by these pathways and may facilitate the discovery of novel therapeutic strategies in areas such as oncology immunology or metabolic research
Medchemexpress LLC Thalidomide 5-fluoride | 835616-61-0 | 100.0% | 276.22 g/mol | C13H9FN2O4 | 25 G
Thalidomide 5-fluoride is a thalidomide-derived cereblon ligand used in targeted protein degradation research and PROTAC synthesis. It is supplied as a high-purity solid and as a DMSO solution, with analytical data and safety documentation available.
- Thalidomide-based cereblon ligand for PROTAC development and E3 ligase recruitment studies.
- Molecular formula C13H9FN2O4; molecular weight 276.22 g/mol.
- High purity (99.96%).
- Available as solid in 1 g, 5 g, 10 g, 25 g quantities.
- Solution option available as 10 mM in DMSO.
- Supplied with supporting documentation including COA, SDS, HNMR, RP-HPLC, and MS.
Medchemexpress LLC 5-fluoro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione | 2230957-36-3 | 97.0% | 290.25 g/mol | C14H11FN2O4 | 5 G
A fluorinated thalidomide analogue that functions as an E3 ligase (Cereblon) activator and a synthetic building block for targeted protein degradation research. Suitable for recruiting CRBN in PROTAC design and for further chemical derivatization via nucleophilic aromatic substitution (SNAr).
- Fluorinated thalidomide analogue
- Acts as an E3 ligase (Cereblon) activator
- Useful as a PROTAC ligand building block
- Compatible with SNAr derivatization
- Typical purity approximately 97.0%
- Molecular formula C14H11FN2O4; molecular weight 290.25 g/mol
Medchemexpress LLC CD3 epsilon 1-27 pep 20ug | 20ug
CD3 epsilon is an important component of the TCR-CD3 complex on T lymphocytes and promotes TCR-mediated signaling When APC activates the TCR CD3 epsilon together with CD3D CD3G and CD3Z transmits signals across the cell membrane through ITAMs CD3 epsilon 1-27 peptide Protein Human (Biotinylated HEK293 hFc-Avi) is the recombinant human-derived CD3 epsilon 1-27 peptide protein expressed by HEK293 with C-Avi C-hFc labeled tag
Medchemexpress LLC CD3 epsilon Canine 50ug | 50ug
The CD3 protein on lymphocytes is a component of the TCR-CD3 complex and is critical for adaptive immune responses When APC is activated TCR signals transmitted by CD3D CD3E CD3G and CD3Z initiate pathways through ITAM CD3 epsilon Protein Canine (HEK293 Fc) is the recombinant canine-derived CD3 epsilon protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Fc epsilon RIA/FCER1 50ug
Recombinant human Fc epsilon RI alpha (extracellular domain) supplied as 50 μg lyophilized material with an N-terminal His-SUMO tag, intended for binding and functional studies involving human IgE.
- Prepared as lyophilized powder for long-term storage and transport.
- Includes N-terminal His-SUMO tag to facilitate affinity purification.
- Expression system: E. coli for efficient production.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Approximate molecular weight ~37 kDa for molecular characterization.
- Demonstrated IgE binding in ELISA with reported ED50 of 5.864 μg/mL.
Cambridge Isotope Laboratories N-METHYLCAPROLACTAM (N-METHYL-D3, 98%), 5 G
N-METHYLCAPROLACTAM (N-METHYL-D3, 98%), 5 G
Medchemexpress LLC CD3 epsilon Rhesus 50ug | 50ug
CD3 epsilon Protein a vital component of the TCR-CD3 complex on T-lymphocytes is pivotal for adaptive immune responses CD3E is crucial for proper T-cell development and contributes to TCR-CD3 complex internalization and down-regulation[1] CD3 epsilon Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived CD3 epsilon protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC CD23/Fc epsilon RII 5ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
