Lactams
Medchemexpress LLC N-Me-thalidomide 4-fluoride | 2244520-92-9 | MFCD34563580 | 99.4% | 290.25 g/mol | C14H11FN2O4 | 1 G
N-Me-Thalidomide 4-fluoride is a research-grade small molecule ligand for E3 ligase used in chemical biology and PROTAC development. It functions as a building block in the synthesis of targeted degraders and related small-molecule tools. Supplied for laboratory research use only.
- Ligand for E3 ligase.
- Useful building block for synthesis of targeted degraders and anti-inflammatory agents.
- High reported purity (99.41%).
- Molecular formula C14H11FN2O4; molecular weight 290.25 g/mol.
- Available in research pack sizes suitable for small-scale synthesis.
Medchemexpress LLC Thalidomide 4-fluoride | 835616-60-9 | 99.9% | 276.22 | 5 G
Thalidomide 4-fluoride is a Thalidomide-based Cereblon ligand that recruits CRBN protein and can be linked to the ligand for IRAK4 protein to create PROTAC IRAK4 degrader-1. This compound targets cereblon (CRBN), a ubiquitous protein involved in the cullin-4 E3 ubiquitin ligase complex CRL4, facilitating the ubiquitination and subsequent proteasomal degradation of target proteins.
- Recruits CRBN protein.
- Can be linked to IRAK4 protein ligand.
- Targets cereblon (CRBN).
- Facilitates ubiquitination and proteasomal degradation of target proteins.
- Molecular weight: 276.22.
- Physical state: solid.
- Color: off-white to gray.
- Soluble in DMSO.
- Store powder at -20°C for 3 years or 4°C for 2 years.
- Store in solvent at -80°C for 2 years or -20°C for 1 year.
- Avoid repeated freeze-thaw cycles after preparation into solution.
Medchemexpress LLC Thalidomide-5-O-C9-NH2 hydrochloride | 451.94 | 5 MG
Thalidomide-5-O-C9-NH2 hydrochloride is a chemical compound primarily used as a laboratory chemical for research purposes and substance manufacturing. It is presented as a solid and is stable under recommended storage conditions.
- Solid appearance
- Stable under recommended storage conditions
- For research use only
Medchemexpress LLC Thalidomide-NH-PEG4-COOH | 2412056-48-3 | 96.7% | 521.52 | 50 MG
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.
- E3 ligase ligand-linker conjugate
- Used for synthesizing dCBP-1
- Potent and selective heterobifunctional degrader of p300/CBP
- Purity of 96.7%
- Appearance: yellow to green (solid-liquid mixture)
- Store at -20°C, protect from light
Medchemexpress LLC Aztreonam | 78110-38-0 | 99.6% | 200 MG
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic that exhibits a very high affinity for penicillin-binding protein 3 (PBP-3). It functions by inhibiting mucopeptide synthesis within the bacterial cell wall, thereby preventing peptidoglycan crosslinking. While resistant to some beta-lactamases, it is inactivated by extended-spectrum beta-lactamases. Aztreonam demonstrates no useful activity against gram-positive or anaerobic microorganisms.
- Inhibits mucopeptide synthesis in bacterial cell walls
- Blocks peptidoglycan crosslinking
- High affinity for penicillin-binding protein 3 (PBP-3)
- Resistant to certain beta-lactamases
- Bactericidal properties
eMolecules 28562-58-5 | 4-Benzoyloxy-2-azetidinone | Combi-Blocks | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 5g | 267200513
4-Benzoyloxy-2-azetidinone | Combi-Blocks | 28562-58-5 | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 5g | 267200513
Research Products International Corp Aztreonam, 1 G
Aztreonam is a synthetic monocyclic beta-lactam antibiotic, with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum.
eMolecules 28562-53-0 | 4-Acetoxy-2-azetidinone | Ambeed | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 250mg | 552638482
4-Acetoxy-2-azetidinone | Ambeed | 28562-53-0 | MFCD00010593 | 129.115 | C5H7NO3 | 97.000 | CC(=O)OC1CC(=O)N1 | 250mg | 552638482
Cayman Chemical Aztreonam-d6 500ug
An internal standard for the quantification of aztreonam by GC- or LC-MS
Research Products International Corp Aztreonam, 100 MG
Aztreonam is a synthetic monocyclic beta-lactam antibiotic, with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum.
