Lactams
Medchemexpress LLC Thalidomide-Piperazine 5-fluoride | 2222114-22-7 | >96.5% | 360.34 | 5 G
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate. Its intended use is for research purposes, specifically in the field of PROTAC (Proteolysis Targeting Chimeras) technology. It incorporates a thalidomide-based cereblon ligand and a linker. This product is not for sale to patients.
- Appearance: Solid, light yellow to green yellow
- Solubility: Soluble in DMSO (5.83 mg/mL or 16.18 mM)
- Storage: 4°C, protect from light; in solvent: -80°C for 6 months, -20°C for 1 month (protect from light)
- Related research areas: Cancer, PROTAC, autophagy, apoptosis, E3 ligase ligand-linker conjugates
- Cereblon ligand: Incorporates a thalidomide-based cereblon ligand
- PROTAC technology: Utilizes a linker commonly used in PROTAC technology
Medchemexpress LLC Thalidomide-Piperazine 5-fluoride | 2222114-22-7 | 96.5% | 360.34 | 1 G
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide based cereblon ligand
- Utilizes linker in PROTAC technology
- For research use only
- Recommended storage at 4°C, protected from light
- Targets E3 Ligase Ligand-Linker Conjugates, Apoptosis, and Autophagy pathways
- Appears as a light yellow to green yellow solid
Medchemexpress LLC Thalidomide-Piperazine 5-fluoride | 2222114-22-7 | 96.47% | 360.34 | 250 MG
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand and a linker utilized in PROTAC technology, designed for research purposes.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates cereblon ligand
- Linker utilized in PROTAC technology
- Intended for research use only
- Purity: 96.47%
- Molecular weight: 360.34
- Solid appearance
- Color: Light yellow to green yellow
- Soluble in DMSO
Medchemexpress LLC Thalidomide-5-CH2-NH2 hydrochloride | 1010100-22-7 | MFCD32666042 | 98.6% | 323.73 | C14H14ClN3O4 | 50 MG
Thalidomide-5-CH2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used as an E3 ligase recruiting moiety in PROTAC design and targeted protein degradation research. Supplied as a solid with high purity, it serves as a linker-compatible building block for medicinal chemistry and chemical biology applications.
- High purity suitable for research.
- Solid form, easy to handle and store.
- Compatible with linker conjugation for PROTAC synthesis.
- Facilitates CRBN-mediated target recruitment.
- Available in multiple small pack sizes for synthesis workflows.
Medchemexpress LLC Thalidomide-5-CH2-NH2 hydrochloride | 1010100-22-7 | MFCD32666042 | 98.6% | 323.73 g/mol | C14H14ClN3O4 | 25 MG
Thalidomide-5-CH2-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt. It provides a reactive primary amine at the 5-position for linker attachment and is used as an E3 ligase recruiting moiety in PROTAC design and related chemical biology research. Suitable for medicinal chemistry and linker-conjugation workflows.