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Thalidomide-pinacolborane is a thalidomide analogue that incorporates a boronic pinacol ester (Bpin). It is used as an E3 ligase ligand in PROTAC research and as a boronate building block for cross-coupling chemistry. Intended for research use only.
Contains a boronic pinacol ester (Bpin) suitable for Suzuki cross-coupling.
Acts as a ligand for E3 ligase in PROTAC applications.
Characterized identity with CAS 2229725-98-6 and molecular weight 384.19.
Purity typically reported as 97.0% by supplier.
Recommended storage under nitrogen at -20°C; in solvent, store at -80°C for up to 6 months.
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Thalidomide-pinacolborane is a thalidomide-derived small molecule bearing a pinacol boronic ester (Bpin). It serves as an E3 ligase (cereblon) ligand useful in targeted protein degradation (PROTAC) research and as a synthetic intermediate for cross-coupling chemistries.
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Thalidomide-pinacolborane is a thalidomide analogue that incorporates a boronic pinacol ester (Bpin). It is used as a synthetic intermediate for cross-coupling chemistry and as an E3 ligase (cereblon) ligand in chemical biology and targeted protein degradation research.
Contains a boronic pinacol ester suitable for Suzuki-Miyaura cross-coupling.
Functions as an E3 ligase (cereblon) ligand for PROTAC and degradation studies.
High purity appropriate for research applications.
Available in research-scale quantities for assay development.
Molecular formula C19H21BN2O6; molecular weight 384.19 g/mol.
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Thalidomide-pinacolborane is a thalidomide analogue containing a pinacol boronate (Bpin) group, supplied as a research reagent for use in synthetic chemistry and chemical biology. It is suitable as a building block for cross-coupling reactions and as a probe to investigate E3 ligase-mediated ubiquitination in degradation studies.
Contains a pinacol boronate functional group for cross-coupling chemistry.
Useful as a synthetic intermediate in Suzuki-Miyaura reactions.
Acts as a thalidomide analogue for studying E3 ligase activity.
Supplied as a high-purity research chemical suitable for analytical and preparative use.
Provided in small-quantity packaging for laboratory experiments.
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Thalidomide-pinacolborane is a thalidomide-derived boronic pinacol ester used as a cereblon (CRBN) ligand for E3 ligase recruitment in PROTAC design and for synthetic transformations such as Suzuki cross-coupling. It is supplied as a solid research reagent intended for use in ligand design, chemical synthesis, and targeted protein degradation studies.
Contains boronic pinacol ester (Bpin) functionality for Suzuki coupling.
Functions as a cereblon E3 ligase ligand suitable for PROTAC applications.
Molecular formula C19H21BN2O6; molecular weight 384.19 g·mol⁻1.
CAS number 2229725-98-6.
Purity 97.0% as listed by the supplier.
Provided as a 25 MG research pack.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More