Lactones
Medchemexpress LLC IFN-gamma Mouse HE 2ug
Recombinant mouse interferon-gamma (IFN-γ) produced in HEK293 mammalian cells. This tag-free, glycosylated cytokine is provided as a high-purity preparation characterized by SDS-PAGE and predicted molecular mass, and is intended for in vitro immunology and cell-signaling studies such as antiviral and macrophage-activation assays.
- Mammalian-expressed for native glycosylation.
- Tag free to avoid interference in receptor binding assays.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Predicted molecular mass 15.5 kDa; observed ~12-21 kDa due to glycosylation.
- Available in small research-appropriate aliquots (for example, 2 μg).
- Includes mature amino acid sequence for reproducibility.
- Suitable for cell signaling, immunology, and antiviral assays.
eMolecules 1823967-74-3 | tert-Butyl 3-(hydroxymethyl)-1H-pyrazole-1-carboxylate | ChemScene | MFCD26519872 | 198.222 | C9H14N2O3 | 97.000 | CC(C)(C)OC(=O)n1ccc(CO)n1 | 100mg | 712787654
tert-Butyl 3-(hydroxymethyl)-1H-pyrazole-1-carboxylate | ChemScene | 1823967-74-3 | MFCD26519872 | 198.222 | C9H14N2O3 | 97.000 | CC(C)(C)OC(=O)n1ccc(CO)n1 | 100mg | 712787654
Selleck Chemical LLC GA-017-E1145-10MM/1ML
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Medchemexpress LLC IFN-gamma R1/CD119 50ug
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
Medchemexpress LLC Interleukin-36 gamma | 50 UG
Recombinant human interleukin-36 gamma (IL-36γ, IL-1F9) is an animal-free, E. coli-expressed cytokine supplied as a lyophilized His-tagged protein. It activates NF-κB and MAPK signaling and induces chemokine expression; biological activity in A431 cells shows an ED50 <5 ng/mL. The product is formulated in PBS with trehalose, has low endotoxin, and is intended for cell-culture research use.
- Lyophilized His-tagged recombinant human IL-36γ.
- Expressed in Escherichia coli to provide animal-free material.
- Approximate molecular weight ~19 kDa by SDS-PAGE.
- Low endotoxin level (<0.1 EU per μg).
- Demonstrated biological activity: ED50 <5 ng/mL (IL-8 induction in A431 cells).
- Formulated in PBS, pH 8.0, with trehalose for stability.
- Reconstitute to 100-200 μg/mL and aliquot to avoid freeze-thaw cycles.
- For research use only; not for therapeutic or human use.
[C@@H]1CO.CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1CO | 1g | 482942929](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502147955.JPG-250.jpg)
eMolecules 123076-44-8 | Cis-3-Hydroxy-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester | J & W PharmLab LLC434.530 | C20H38N2O8 | 97.000 | CC(C)(C)OC(=O)N1CC[C@H](O)[C@@H]1CO.CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1CO | 1g | 482942929
Cis-3-Hydroxy-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester | J & W PharmLab LLC | 123076-44-8434.530 | C20H38N2O8 | 97.000 | CC(C)(C)OC(=O)N1CC[C@H](O)[C@@H]1CO.CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1CO | 1g | 482942929
Medchemexpress LLC IFN-gamma Canine 100ug | 100ug
IFN-gamma (interferon-gamma) is a type II interferon produced by immune cells such as T cells and NK cells and plays a key role in activating antibacterial antiviral and antitumor responses Through the JAK-STAT pathway its interaction with the receptor IFNGR1 triggers gene regulation IFN-gamma Protein Canine is the recombinant canine-derived IFN-gamma protein expressed by E coli with tag free
Sigma Aldrich Fine Chemicals Biosciences delta-Decalactone >=98%, FCC, FG | 705-86-2 | MFCD00006649 |
delta-Decalactone >=98%, FCC, FG | Purity: >=98% | Mol Wt: 170.25 | 705-86-2 | MFCD00006649 |
Sigma Aldrich Fine Chemicals Biosciences Pilocarpine hydrochloride >=99% (titration), powder | 54-71-7 | MFCD00012722 | 50G
Pilocarpine hydrochloride >=99% (titration), powder | Purity: >=99% (titration) | Mol Wt: 244.72 | 54-71-7 | MFCD00012722 | 50G
![Medchemexpress LLC 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid | 960201-81-4 | 99.1% | 329.35 g/mol | C18H19NO5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241614.png-250.jpg)
Medchemexpress LLC 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid | 960201-81-4 | 99.1% | 329.35 g/mol | C18H19NO5 | 5 MG
SD-1008 is a small-molecule JAK inhibitor (CAS 960201-81-4) used in research to block tyrosyl phosphorylation of STAT3, JAK2, and Src and to enhance apoptosis in sensitive cell lines. It is supplied as a high-purity, solid reagent for biochemical and cellular studies.
- Potent inhibition of JAK/STAT3 signaling, reducing phosphorylation of STAT3, JAK2, and Src.
- High purity suitable for biochemical and cellular assays.
- Molecular weight 329.35 g/mol and formula C18H19NO5 for accurate dosing.
- Light yellow solid appearance, convenient for handling and dissolution.
- Multiple package sizes available to support assay development and screening.
- Storage recommendations: protect from light, store under inert gas, and maintain cold storage for solutions.
C[C@@H]1CO | 1g | 417005769](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171785.JPG-250.jpg)
eMolecules 1279039-34-7 | (2R,4S)-1-BOC-2-HYDROXYMETHYL-4-AMINO PYRROLIDINE HCL | AstaTech252.740 | C10H21ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)N1C[C@@H](N)C[C@@H]1CO | 1g | 417005769
(2R,4S)-1-BOC-2-HYDROXYMETHYL-4-AMINO PYRROLIDINE HCL | AstaTech | 1279039-34-7252.740 | C10H21ClN2O3 | 95.000 | Cl.CC(C)(C)OC(=O)N1C[C@@H](N)C[C@@H]1CO | 1g | 417005769
Medchemexpress LLC Gamma-secretase modulator 1 | 1172637-87-4 | 98.0% | 416.54 | C24H24N4OS | 100 MG
Gamma-secretase modulator 1 is a research-grade small molecule that modulates γ-secretase activity and is used to study amyloid-β production and Alzheimer's disease mechanisms. It is supplied as a high-purity solid suitable for in vitro and mechanistic research.
- High purity (98.0%) for reproducible experimental results.
- Characterized molecular properties: C24H24N4OS, MW 416.54.
- Suitable for in vitro and mechanistic studies of γ-secretase and amyloid-β production.
- Supplied as a solid with multiple pack size options.
- Stable when stored under recommended conditions for research reagents.