Lactones
Sigma Aldrich Fine Chemicals Biosciences (+)-gamma-Decalactone natural, >=97%, FG | 706-14-9 | MFCD23704512 | 1KG
(+)-gamma-Decalactone natural, >=97%, FG | Purity: >=97% | 706-14-9 | MFCD23704512 | 1KG
Selleck Chemical LLC GA-017-E1145-25MG
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2) which exerts inhibitory with IC50s against LATS1 and 2 of 4 10 0 79 and 3 92 0 42 nM respectively and competitively inhibits LATS1 and 2 against ATP with Ki (inhibition constant) values of 0 58 0 11 and 0 25 0 03 nM respectively
Sigma Aldrich Fine Chemicals Biosciences gamma Valerolactone 99 FCC10KG
I3-Valerolactone has been identified as one of the volatile flavor constituents in mango and honey.
AdipoGen Butyrolactone 3
Chemical. CAS 778649-18-6. Formula C9H12O4. MW 184.2. Synthetic Specific histone acetyltransferase Gcn5 inhibitor. Anticancer compound. Pre-mRNA splicing inhibitor. Blocks splicing before the first catalytic steps. Potential anti-inflammatory compound.
Medchemexpress LLC Propiolactone | 57-57-8 | 99.36% | 72.06 | 25 MG
Propiolactone (β-propiolactone; 2-Oxetanone) is a viral chemical inactivator that causes the infectious inactivation of viruses. It has been used to inactivate SARS-CoV and as a bacteriostatic agent to formulate the BPL-inactivated influenza virus vaccine (Flu-BPL).
- Causes infectious inactivation of viruses.
- Used as a bacteriostatic agent to formulate BPL-inactivated influenza virus vaccine.
- Can be used for vaccine purification.
- Inactivated virus loses infectivity in Vero cells.
Medchemexpress LLC Butyrolactone 3 | 778649-18-6 | 99.6% | 25 MG
Butyrolactone 3 (MB-3) is a specific small-molecule inhibitor of the histone acetyltransferase Gcn5, demonstrating an IC50 of 100 μM. It shows high affinity for the Gcn5 enzyme, similar to its natural substrate histone H3, while exhibiting weak inhibitory activity on CBP (IC50=0.5 mM). This compound is valuable for research in cancer, metabolic, autoimmune, and neurological diseases.
- Specific small-molecule inhibitor of histone acetyltransferase Gcn5
- High affinity for the Gcn5 enzyme
- Weak inhibitory activity on CBP
- Useful in studies related to cancer, metabolic, autoimmune, and neurological diseases
- Reduces Gcn5 acetylation
- Induces E2A-PBX1 degradation
- Decreases protein levels of E2A-PBX1, E2A, Wnt16, and GCN5 in RCH-ACV cells
Medchemexpress LLC AP-2 gamma/TFAP2C protein, human (His) | >95.0% | 100 UG
Recombinant human AP-2 gamma/TFAP2C protein fragment (residues L128-V223) expressed in E. coli with an N-terminal 10xHis tag. Supplied as a sterile, lyophilized powder from PBS (pH 7.4), the product is >95% pure and intended for biochemical and DNA-binding assays. Store frozen and follow recommended reconstitution and aliquoting practices for stability.
- Residues L128-V223 representing the human TFAP2C fragment.
- N-terminal 10xHis tag for affinity purification.
- Expression system: E. coli.
- Molecular weight approximately 10-14 kDa.
- Purity greater than 95.0% by reducing SDS-PAGE.
- Lyophilized from 0.22 μm filtered PBS, pH 7.4.
- Recommended reconstitution concentration not less than 100 μg/mL.
- Storage: -20°C up to 2 years; after reconstitution stable at 4°C for 1 week.
- Available in multiple sizes, including 100 μg.
Medchemexpress LLC p38 gamma (MAPK12) protein, human | >95.0% | 50 UG
Recombinant, tag-free human p38 gamma (MAPK12) protein supplied as a filtered buffered solution for biochemical and cell-based research. The protein is full-length and prepared to support kinase-related assays and binding studies while minimizing contaminants and endotoxin.
- Full-length human sequence (M1-L367).
- Expressed in Sf9 insect cells to support eukaryotic folding and modifications.
- Tag free to avoid interference in interaction studies.
- Purity >95.0% as determined by reducing SDS-PAGE.
- Supplied in 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0 (0.22 μm filtered solution).
- Endotoxin <1 EU/μg, determined by LAL.
- Shipped on dry ice and recommended storage at -80°C for long-term stability.
Medchemexpress LLC AP-2 gamma (TFAP2C) protein, human, recombinant, His-tagged | >95.0% | 500 UG
Recombinant human AP-2 gamma/TFAP2C protein (His-tagged), covering residues L128-V223, supplied as a lyophilized powder. Suitable for biochemical and binding assays, structural studies, and antibody validation, the product is expressed in E. coli and provided with quality documentation.
Medchemexpress LLC Gamma-secretase modulator 2 | 1093978-89-2 | 98.8% | C25H22F4N6O2 | 1 ML
Gamma-secretase modulator 2 is a potent and selective gamma-secretase modulator. It is used for the study of Alzheimer's disease and is intended for research use only.
- Potent and selective gamma-secretase modulator
- Appears as a solid
- Color is white to off-white
- Soluble in DMSO at 100 mg/mL
- Useful for research in neurological and neurodegenerative diseases
Medchemexpress LLC gamma-Glutamylarginine | 31106-03-3 | 303.31 | 100 MG
gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine) is an γ-glutamic acid oligopeptide that can be isolated from Panax ginseng. It is intended for research use only.
- An γ-glutamic acid oligopeptide
- Can be isolated from Panax ginseng
- For research use only
Medchemexpress LLC Recombinant rat interferon-gamma receptor 1 (IFN-gamma R1/CD119), Fc-tagged | >=95% | 10 UG
Recombinant rat interferon-gamma receptor 1 (IFN-gamma R1/CD119) produced in HEK293 cells with a C-terminal human Fc tag. Supplied as a 10 μg research reagent with purity ≥95%; intended for receptor binding, signaling, and analytical assays.
- Recombinant rat IFN-gamma receptor 1 extracellular domain (M1-S241).
- Produced in HEK293 cells for mammalian expression and proper folding.
- C-terminal hFc tag to aid purification and detection.
- Purity ≥95% as reported by the supplier.
- Supplied as 10 μg suitable for in vitro assays.
- For research use in receptor binding, signaling, and analytical applications.