Oxazinanes
TARGETMOL CHEMICALS INC Aneratrigine hydrochloride 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Aneratrigine hydrochloride is a sodium channel protein type 9 subunit blocker that may be used for the prevention or treatment of sodium channel blocker-related diseases. Purity 99.39%
Selleck Chemical LLC Dasatinib hydrochloride S5254-10mM/1mL
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib an inhibitor that targets Abl Src and c-Kit with IC50 of 1 nM 0 8 nM and 79 nM in cell-free assays respectively
Selleck Chemical LLC Acotiamide hydrochloride S4838-25mg
Acotiamide Hydrochloride (YM-443 Z-338) is the hydrochloride salt form of acotiamide a prokinetic agent with gastrointestinal (GI) motility-enhancing activity It is a new orally active selective acetylcholinesterase inhibitor
TARGETMOL CHEMICALS INC Sonlicromanol hydrochloride
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases. Purity 99.53%
Selleck Chemical LLC N6F11-E1812-250MG
N6F11 is an inducer of ferroptosis N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4) resulting in proteasomal degradation
Apexbio Technology LLC Lofexidine (hydrochloride) 21498-08-8 10mM (in 1mL H2O)
Lofexidine hydrochloride (CAS 21498-08-8) is a selective 2-adrenergic receptor agonist demonstrating high affinity for the 2A-receptor subtype By activating presynaptic 2-adrenergic autoreceptors in the central nervous system lofexidine modulates noradrenergic neurotransmission which is implicated in opioid withdrawal physiology Following oral administration lofexidine is extensively absorbed with peak plasma concentrations achieved within approximately 3 hours Clinically it has been investigated for the management of opioid withdrawal symptoms with reported adverse effects including insomnia dry mucous membranes sedation dizziness and asthenia Lofexidine serves as a research tool in studies of adrenergic receptor pharmacology and opioid detoxification
Selleck Chemical LLC Tinoridine hydrochloride
Tinoridine hydrochloride (Y-3642) is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity
Selleck Chemical LLC Prilocaine hydrochloride
Prilocaine hydrochloride is the hydrochloride salt form of prilocaine which is a local anesthetic
eMolecules Combi-Blocks (R)-tert-Butyl azepan-3-ylcarbamate 5g 457918329 QM-7710 97.000 1354351-56-6 MFCD19686115 214.309 C11H22N2O2
Combi-Blocks (R)-tert-Butyl azepan-3-ylcarbamate 5g 457918329 QM-7710 97.000 1354351-56-6 MFCD19686115 214.309 C11H22N2O2
Selleck Chemical LLC Thioridazine hydrochloride
Thioridazine (Aldazine Mellaril) is a potent antianxiety and antipsychotic agent
Medchemexpress LLC Iadademstat (dihydrochloride) | 1431303-72-8 | 100.0% | 100 MG
Iadademstat dihydrochloride is a selective irreversible lysine (K)-specific demethylase 1A (KDM1A/LSD1) inhibitor. It inactivates KDM1A by irreversibly binding to the flavin adenine nucleotide (FAD) cofactor. This compound shows high selectivity for KDM1A over MAO enzymes and KDM1B, and potent subnanomolar cellular activity against mixed lineage leukemia (MLL)-translocated acute myeloid leukemia (AML) cell lines. It reduces AML tumor growth in animal xenografts and prolongs survival in T-ALL models.
- Selective irreversible KDM1A/LSD1 inhibitor
- Inactivates KDM1A by binding to FAD cofactor
- High selectivity for KDM1A over MAO enzymes and KDM1B
- Potent subnanomolar cellular activity against MLL-translocated AML cell lines
- Reduces AML tumor growth in animal xenografts
- Prolongs survival in disseminated T-ALL models
Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 10mM (in 1mL DMSO)
GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
Medchemexpress LLC Elacestrant dihydrochloride | 1349723-93-8 | 99.5% | 531.56 | 5 MG
Elacestrant dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) that inhibits the growth of ER+ breast cancer cell lines both in vitro and in vivo. It has IC50s of 48 nM for ERα and 870 nM for ERβ. This product is for research use only and not sold to patients.
- Orally available and selective estrogen receptor degrader
- Inhibits the growth of ER+ breast cancer cell lines
- For research use only
- Appearance: white to off-white solid
- Shipped at room temperature
- Stored at 4°C, sealed, away from moisture
- In solvent, stored at -80°C for 6 months or -20°C for 1 month
eMolecules Ambeed / 2-Methyl-3-(trifluoromethyl)aniline / 1g / 562292624 / A201436 / / 54396-44-0 / MFCD00153216 / 175.154 / C8H8F3N
Ambeed / 2-Methyl-3-(trifluoromethyl)aniline / 1g / 562292624 / A201436 / / 54396-44-0 / MFCD00153216 / 175.154 / C8H8F3N