Oxazinanes
TARGETMOL CHEMICALS INC SELVIGALTIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer. purity: 99%
Selleck Chemical LLC Harmine hydrochloride S3817-1g
Harmine (Telepathine) a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A with about 60-fold higher IC50 value for DYRK2 Harmine also inhibits monoamine oxidases (MAOs) PPAR and cdc-like kinases (CLKs) Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM
![eMolecules 1818843-14-9 | TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697439.jpg-250.jpg)
eMolecules 1818843-14-9 | TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062
TERT-BUTYL N-[(2R)-AZETIDIN-2-YLMETHYL]CARBAMATE HCL | AstaTech | 1818843-14-9 | MFCD28893974 | 222.710 | C9H19ClN2O2 | 95.000 | Cl.CC(C)(C)OC(=O)NC[C@H]1CCN1 | 1g | 449781062
![eMolecules 152140-65-3 | Ambeed | NN-(11R12R)-(910-Dihydro-910-ethanoanthracene-1112-diyl)bis[2-(diphenylphosphino)benzamide] | 100mg | 595929513 | A790190 | 812.89 | C54H42N2O2P2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502452885.PNG-250.jpg)
eMolecules 152140-65-3 | Ambeed | NN-(11R12R)-(910-Dihydro-910-ethanoanthracene-1112-diyl)bis[2-(diphenylphosphino)benzamide] | 100mg | 595929513 | A790190 | 812.89 | C54H42N2O2P2
Ambeed | O-(4-Methoxybenzyl)hydroxylamine | 1g | 592393493 | A184536 | 21038-22-2 | MFCD01722038 | 153.181 | C8H11NO2
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Apexbio Technology LLC Isoxsuprine (hydrochloride) 579-56-6 10mM (in 1mL DMSO)
Isoxsuprine hydrochloride (CAS 579-56-6) is a small molecule that modulates 2-adrenergic receptors a class of G protein-coupled receptors responsive to epinephrine and implicated in sympathetic nervous system signaling including smooth muscle relaxation and vasodilation Isoxsuprine functions as both an agonist and antagonist at these receptors In vitro Isoxsuprine has demonstrated preservation of neuronal viability when administered following hypoxic insult In vivo studies using stroke models show that post-ischemic administration of Isoxsuprine significantly reduces infarct volume These properties support its use in investigating neuroprotection cerebrovascular modulation and smooth muscle physiology
AdipoGen CX-4945 HCl
Chemical. CAS 1009820-21-6 free acid. Formula C19H12ClN3O2 . HCl. MW 349.8 . 36.5. Synthetic. Orally active, potent and selective ATP-competitive inhibitor of the protein kinase CK2 IC50=1nM. Anticancer compound. Inhibits proliferation in a panel of cancer cell lines that overexpress CK2. Inhibited migration, blocks survival and induces apoptosis in cancer stem cells, glioblastomas and leukemia cells. Shown to decrease the glucose metabolism in cancer cells. Potent inhibitor of Cdc2-like kinases Clks in vitro, consequently interfering with alternative splicing. Potent ATP-competitive inhibitor of DYRK1A IC50=6.8 nM, involved in neurodegenration-associated diseases. CK2alpha deletion selectively increased M3 muscarinic receptors M3Rs-mediated insulin secretion from pancreatic islets. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis.
Selleck Chemical LLC Irinotecan hydrochloride S5026-1g
Irinotecan (CPT-11 ( )-Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15 8 M and 5 17 M respectively
Selleck Chemical LLC Atipamezole hydrochloride S4649-50mg
Atipamezole (Antisedan MPV1248) is a synthetic 2 adrenergic receptor antagonist It has also been researched in humans as a potential anti-Parkinsonian drug Atipamezole hydrochloride is hydrochloride form of atipamezole
Medchemexpress LLC Rhodamine B isothiocyanate | 36877-69-7 | MFCD00041787 | 98.0% | 536.09 g/mol | C29H30ClN3O3S | 5 MG
Rhodamine B isothiocyanate is a xanthene-derived fluorescent labeling reagent containing an isothiocyanate functional group for covalent conjugation to primary amines. Provided as a solid, it produces strong red fluorescence for biochemical labeling, microscopy, and fluorescence assays, and is suitable for preparing labeled proteins, peptides, and other biomolecules.
- Provides bright red fluorescence for sensitive detection and imaging.
- Reacts with primary amines via isothiocyanate chemistry for stable covalent labeling.
- High purity (~98.0%) for reproducible conjugation results.
- Solid form allows easy handling and long-term storage when protected from light.
- Compatible with common fluorescence detection systems and imaging filters.
Selleck Chemical LLC Trihexyphenidyl hydrochloride S4542-100mg
Trihexyphenidyl hydrochloride (Benzhexol Artane) is an antiparkinsonian agent of the antimuscarinic class
Selleck Chemical LLC N6F11-E1812-250MG
N6F11 is an inducer of ferroptosis N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4) resulting in proteasomal degradation
Selleck Chemical LLC Mebeverine Hydrochloride S5027-25mg
Mebeverine (Duspatalin Duspatal Colofac) a 3-phenylethylamine derivative of methoxybenzamine acts as a musculotropic antispasmodic agent
Selleck Chemical LLC Dasatinib hydrochloride S5254-10mM/1mL
Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib an inhibitor that targets Abl Src and c-Kit with IC50 of 1 nM 0 8 nM and 79 nM in cell-free assays respectively