Oxazinanes
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM
Sigma Aldrich Fine Chemicals Biosciences Coniine hydrochloride phyp20MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG
Cayman Chemical 3 4DIhydroxymndelIc AcId 250mg
An active metabolite of norepinephrine; scavenges superoxide radicals (IC50 = 130 nM) and reduces lipid peroxidation in cell-free assays; a chemoattractant for enterohemorrhagic E. coli; induces the expression of enterohemorrhagic E. coli virulence genes at 50 µM; increases the attachment of enterohemorrhagic E. coli to HeLa cells in vitro
![eMolecules 2-Morpholin-4-Yl-2-[4-(Trifluoromethyl)Phenyl]Ethylamine | 885950-67-4 | 1G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-386898219.PNG-250.jpg)
eMolecules 2-Morpholin-4-Yl-2-[4-(Trifluoromethyl)Phenyl]Ethylamine | 885950-67-4 | 1G
Chem-Impex | 2-Morpholin-4-Yl-2-[4-(Trifluoromethyl)Phenyl]Ethylamine | 1G | 885950-67-4 | MFCD10696344 | MW:268.316
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Apexbio Technology LLC SKF 525A (hydrochloride) 62-68-0 1g
SKF 525A (hydrochloride CAS 62-68-0) is a small-molecule inhibitor of cytochrome P450 (CYP) enzymes It modulates CYP-mediated metabolic pathways by inhibiting several isoforms including CYP2B6 CYP2C9 CYP2C19 CYP2D6 and CYP3A with limited impact on CYP1A2 CYP2A6 and CYP2E1 When assessed in human liver microsomes SKF 525A demonstrates CYP-dependent N-deethylation and exhibits inhibitory potency in the micromolar range In animal models it non-specifically disrupts sympathetic ganglia and adrenal medulla signaling possibly by stabilizing postsynaptic membranes SKF 525A is commonly used to study drug metabolism and CYP-mediated biotransformation in preclinical settings
eMolecules ChemScene / N1-Methylbenzene-13-diamine / 250mg / 632276133 / CS-0019198 / 0.000 / 50617-73-7 / MFCD11132708 / 122.171 / C7H10N2
ChemScene / N1-Methylbenzene-13-diamine / 250mg / 632276133 / CS-0019198 / 0.000 / 50617-73-7 / MFCD11132708 / 122.171 / C7H10N2
Sigma Aldrich Fine Chemicals Biosciences Bestatin hydrochloride 9810MG
Chemical structure amino acid derivatives
eMolecules 2-(Cyclohexylsulfanyl)benzene-1,4-diol | 441764-31-4 | MFCD03273483 | 250mg
Oakwood Chemical | 2-(Cyclohexylsulfanyl)benzene-1,4-diol | 250mg | 537712690 | 181113 | | 441764-31-4 | MFCD03273483 | 224.320 | C12H16O2S
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TARGETMOL CHEMICALS INC DASOTRALINE HYDROCHLORID 50MG
Also available in 5 mg 10 mg 25 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine norepinephrine and serotonin transporters with IC50 values of 4 6 and 11 nM respectively. purity: 99%
Apexbio Technology LLC THZ1 Hydrochloride 1604810-83-4 (free base) 10mM (in 1mL DMSO)
THZ1 Hydrochloride is a covalent inhibitor targeting the cyclin-dependent kinase CDK7 with an IC50 of approximately 3 2 nM Mechanistically THZ1 modifies CDK7 by covalently binding to a cysteine residue located outside the kinase domain thereby inhibiting kinase-mediated phosphorylation events associated with the RNA Polymerase II C-terminal domain (CTD) It perturbs transcriptional regulation pathways mediated by CDK7-related signaling in cells including inhibition of phosphorylation essential for initiation and elongation processes THZ1 has demonstrated inhibitory activity in various cancer cell lines particularly in T-cell acute lymphoblastic leukemia (T-ALL) cell lines such as Jurkat and Loucy where sensitivity correlates with interference of RUNX1 transcriptional programs THZ1 is primarily used as a pharmacological tool to investigate CDK7-driven transcriptional regulation and tumor biology
Cayman Chemical Pargyline hydrochloride
An irreversible inhibitor of MAO (Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively); induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats; prevents reactive oxygen species-mediated monocyte hypertrophy at a concentration of 10 µM