Oxazinanes
TARGETMOL CHEMICALS INC NF-56-EJ40 HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg and bulk. Please contact Fisher for quotes. NF-56-EJ40 hydrochloride is a potent high-affinity and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM. purity: 97%
Medchemexpress LLC 7-Ethylcamptothecin | 78287-27-1 | 250 MG
7-Ethylcamptothecin is a derivative of Camptothecin and a DNA topoisomerase I inhibitor. It exhibits significant antitumor activity against tumor cells and serves as a key precursor for the synthesis of 20 (S)-O-substituted benzoyl-7-ethylcamptothecin compounds. It is widely used in various tumor-related scientific studies.
- Functions as a DNA topoisomerase I inhibitor.
- Exhibits significant antitumor activity against tumor cells.
- Serves as a precursor for synthesizing 20 (S)-O-substituted benzoyl-7-ethylcamptothecin compounds.
- Utilized in various tumor-related scientific studies.
- Starting material for developing E-ring modified water-soluble camptothecin derivatives.
- Appears as a light yellow to yellow solid.
- Has a purity of 99.58%.
Selleck Chemical LLC Triflupromazine hydrochloride
Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class
Selleck Chemical LLC Moxisylyte hydrochloride
Moxisylyte hydrochloride (thymoxamine) is an alpha-adrenergic blocking agent used for the treatment of Raynaud s disease
Selleck Chemical LLC KHS101 hydrochloride
KHS101 is a small-molecule inhibitor of TACC3 which is a key component of centrosome-microtubule dynamic networks
Selleck Chemical LLC Midodrine hydrochloride
Midodrine hydrochloride is the hydrochloride salt form of midodrine an adrenergic alpha-1 agonist used as a vasopressor
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-1,2,3-triazole | ChemScene | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 1g | 536782377
4-Bromo-2-methyl-2H-1,2,3-triazole | ChemScene | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 1g | 536782377
eMolecules 16681-67-7 | 4-bromo-2-methyl-2H-1,2,3-triazole | Pharmablock | MFCD23378485 | 161.990 | C3H4BrN3 | 97.000 | Cn1ncc(Br)n1 | 50mg | 761954540
4-bromo-2-methyl-2H-1,2,3-triazole | Pharmablock | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 97.000 | Cn1ncc(Br)n1 | 50mg | 761954540
Medchemexpress LLC 13,14-dihydro-15-keto prostaglandin D2 | 59894-07-4 | MFCD00885499 | 99.9% | 352.47 | C20H32O5 | 1 MG
13,14-dihydro-15-keto prostaglandin D2 is a chemically defined metabolite of prostaglandin D2 supplied as a high-purity research standard for analytical and pharmacological studies. It is provided as a solution in methyl acetate and intended for use as an analytical reference or reagent in biochemical assays.
- High purity analytical standard (99.9%).
- Chemical formula C20H32O5; molecular weight 352.47 g/mol.
- Supplied as a solution in methyl acetate for convenient handling.
- Provided in small milligram-scale quantities suitable for standards and assays.
- Store solution at -20°C; stable for up to 2 years when stored properly.
- Documentation available: certificate of analysis and safety data sheet.
Selleck Chemical LLC Bobcat339 hydrochloride
Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 M and 73 M for TET1 and TET2 respectively Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe
Medchemexpress LLC Sapropterin dihydrochloride (standard) | 69056-38-8 | 100.0% | C9H17Cl2N5O3 | 5 MG
Sapropterin dihydrochloride (Standard) is the analytical standard of Sapropterin (dihydrochloride), intended for research and analytical applications. It functions as an orally active phenylalanine hydroxylase (PAH) cofactor, reducing blood phenylalanine concentrations, and is used in the study of phenylketonuria (PKU). Additionally, it can aggravate experimental autoimmune encephalomyelitis (EAE).
- Analytical standard for research and analytical applications
- Orally active phenylalanine hydroxylase (PAH) cofactor
- Reduces blood phenylalanine concentrations
- Used in the study of phenylketonuria (PKU)
- Can aggravate experimental autoimmune encephalomyelitis (EAE)
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | 99.79% | 239.23 | 100 MG
7,8-Dihydro-L-biopterin is a NOS uncoupling inducer that can cross the blood-brain barrier. It is a reduced non-conjugated pteridine and the main metabolite of 4-amino-tetrahydro-L-biopterin, which undergoes photooxidation to form biopterin. This compound promotes the conversion of nitric oxide synthase to a superoxide-producing form, leading to increased oxidative stress in the renal outer medulla and inducing apoptosis.
- NOS uncoupling inducer
- Can cross the blood-brain barrier
- Promotes conversion of nitric oxide synthase to a superoxide-producing form
- Increases oxidative stress in the renal outer medulla
- Induces apoptosis
- Sensitive to inhibitory effect of SOD
- Used in research related to salt-sensitive hypertension and neurodegenerative diseases
Apexbio Technology LLC Midodrine (hydrochloride) 43218-56-0 250mg
Midodrine hydrochloride (CAS 43218-56-0) is a prodrug that is metabolized to desglymidodrine a selective agonist of 1-adrenergic receptors It exhibits binding affinities (Ki) of 2 M 6 9 M and 1 7 M for the 1A 1B and 1D receptor subtypes respectively Activation of these receptors mediates vasoconstriction in arteriolar and venous smooth muscle resulting in increased vascular tone and blood pressure Preclinical studies have also shown that central administration of midodrine affects thermoregulation and locomotor activity in animal models Research applications include investigation of adrenergic signaling cardiovascular regulation and combination therapy for refractory ascites
Apexbio Technology LLC W-13 hydrochloride 88519-57-7 1mg
W-13 hydrochloride (CAS 88519-57-7) is a small molecule inhibitor that acts as an antagonist of calmodulin thereby modulating calmodulin-dependent signaling pathways and influencing intracellular calcium homeostasis Studies have demonstrated that W-13 hydrochloride suppresses the proliferation of human breast cancer cells resistant to tamoxifen indicating its utility in investigating mechanisms underlying cancer drug resistance This compound is widely employed in biomedical research to dissect calmodulin-mediated signaling and to explore pathways involved in the adaptive responses of tumor cells
TARGETMOL CHEMICALS INC PF-543 HYDROCHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. purity: 99%