Oxazinanes
Aobchem 5 8-Dibromo-2 3-dihydro-1 4-benzodioxin | 97% | CAS 2385024-17-7 | C8H6Br2O2 | 1g
5 8-Dibromo-2 3-dihydro-1 4-benzodioxin | 97% | CAS 2385024-17-7 | C8H6Br2O2 | 1g
Cayman Chemical FR122047 (hydrochloride), Purity: ≥98%, CAS: 130717-51-0, 5 mg
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis
Cayman Chemical Methyl-L-NIO (hydrochloride), Purity: ≥98%, CAS: 150403-96-6, 10 mg
A competitive NOS inhibitor; more potent inhibitor of nNOS (Ki = 3.0 µM) than eNOS (Ki = 10.0 µM) or iNOS (Ki = 9.5 µM)
Cayman Chemical Trimidox (hydrochloride), Purity: ≥98%, CAS: 95933-75-8, 10 mg
A specific ribonucleotide reductase inhibitor; inhibits growth of human promyelocytic leukemia HL-60 cells (IC50 = 35 µM)
Cayman Chemical GW 3965 (hydrochloride), Purity: ≥98%, CAS: 405911-17-3, 10 mg
An orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively; alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism
Cayman Chemical DL-threo-PDMP (hydrochloride), Purity: ≥98%, CAS: 80938-69-8, 100 mg
An inhibitor of sphingolipid biosynthesis; inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates at 5 and 10 µM; reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest; increases Aβ42 and Aβ39 production independent of ceramide metabolism via modulation of γ-secretase activity
Cayman Chemical FR122047 (hydrochloride), Purity: ≥98%, CAS: 130717-51-0, 1 mg
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis
![Aobchem Ethanone 1-(3 -chloro[1 1 -biphenyl]-3-yl)- | ≥97% | CAS 893734-53-7 | C14H11ClO | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000979889.png-250.jpg)
Aobchem Ethanone 1-(3 -chloro[1 1 -biphenyl]-3-yl)- | ≥97% | CAS 893734-53-7 | C14H11ClO | 1g
Ethanone 1-(3 -chloro[1 1 -biphenyl]-3-yl)- | ≥97% | CAS 893734-53-7 | C14H11ClO | 1g
Aobchem 7-Methoxy-1H-indazole-4-boronic acid | ≥97% | CAS 2121513-25-3 | C8H9BN2O3 | 500mg
7-Methoxy-1H-indazole-4-boronic acid | ≥97% | CAS 2121513-25-3 | C8H9BN2O3 | 500mg
Aobchem 3-Methyl-4-(methylsulfanyl)benzoic acid | ≥95% | CAS 851669-34-6 | C9H10O2S | 5g
3-Methyl-4-(methylsulfanyl)benzoic acid | ≥95% | CAS 851669-34-6 | C9H10O2S | 5g
Aobchem (3-Cyano-4-ethoxyphenyl)boronic acid | ≥95% | CAS 279262-20-3 | C9H10BNO3 | 5g
(3-Cyano-4-ethoxyphenyl)boronic acid | ≥95% | CAS 279262-20-3 | C9H10BNO3 | 5g
Aobchem 4-Bromo-2 3-dihydro-1H-indene | ≥97% | CAS 6134-53-8 | C9H9Br | 250mg
4-Bromo-2 3-dihydro-1H-indene | ≥97% | CAS 6134-53-8 | C9H9Br | 250mg