Oxazinanes
TARGETMOL CHEMICALS INC ZK-90055 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ZK-90055 hydrochloride is a (beta)2 adrenergic receptor agonist used to study asthma. purity: 99%
Cayman Chemical 3-OxocholIc AcId 250mg
A secondary bile acid; a metabolite of cholic acid in C. perfringens; serum levels increase following ileal transposition surgery in rats
TARGETMOL CHEMICALS INC SAMURACICLIB HYDROCHLORI 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent selective ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45- 15- 230- and 30-fold higher than CDK1 CDK2 (IC50 is 578 nM) CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 uM. Samuraciclib hydrochloride has anti-tumor effects. purity: 99%
TARGETMOL CHEMICALS INC LY266097 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LY266097 hydrochloride (LY 266097 hydrochloride) is an antagonist of 5-HT2 with pKis of 7.7 9.8 and 7.6 for human 5-HT2A 5-HT2B and 5-HT2C and can be used in studies about depression. purity: 99%
TARGETMOL CHEMICALS INC AZEPEXOLE HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Azepexole hydrochloride (4H-Oxazolo[45-d]azepin-2-amine 6-ethyl-5678-tetrahydro- hydrochloride (11)) is a potent (alpha)2-Adrenoceptor agonist with anaesthetic effects. purity: 99%
TARGETMOL CHEMICALS INC Protriptyline hydrochloride
Also available in 1 mL, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. In addition, this agent exhibits anticholinergic activity. Purity 99.98%
Selleck Chemical LLC Ligustrazine hydrochloride S3775-25mg
Ligustrazine hydrochloride (Tetramethylpyrazine Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation antioxidant antiplatelet and antiapoptosis activities
Medchemexpress LLC HADA hydrochloride | 2253733-10-5 | 98.0% | 1 ML
HADA hydrochloride is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation.
- Blue fluorescent D-amino acid
- Efficiently incorporated into peptidoglycans of diverse bacterial species
- Allows specific and covalent probing of bacterial growth
- Minimal perturbation during bacterial growth probing
- Suitable for laboratory research applications
Medchemexpress LLC 4-Phenyl-7,8-dihydroxycoumarin | 842-01-3 | 99.4% | 1 ML
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative primarily used for bronchiectasis research. It is intended for research use only and not for medical applications.
- High purity (99.35%)
- Supplied as a 10 mM solution in DMSO
- Appearance: off-white to yellow solid
- Molecular weight: 254.24
- Demonstrates cytotoxicity against human A375 cells with an IC50 of 39 μM
- Demonstrates cytotoxicity against human MRC5 cells with an IC50 of 47 μM
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Bomedemstat dihydrochloride | 99.6% | 592.54 | 100 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, altering gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis.
- Increases H3K4 and H3K9 methylation
- Alters gene expression
- Inhibits cancer cell proliferation
- Induces apoptosis
Medchemexpress LLC Bomedemstat dihydrochloride | 99.55% | 592.54 | 25 MG
Bomedemstat dihydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. It increases H3K4 and H3K9 methylation, which then alters gene expression. This compound exhibits anti-cancer activities by inhibiting cancer cell proliferation and inducing apoptosis, and is being investigated in multiple clinical trials.
- Selectively inhibits proliferation of Jak2V617F cells
- Induces apoptosis via BCL-XL and PUMA in a TP53-dependent manner
- Leads to cell cycle arrest in SET-2 cells
- Normalizes or improves blood cell counts in Mx-Jak2V617F mice
- Reduces spleen volumes and restores normal splenic architecture in animal models
Apexbio Technology LLC PJ34 hydrochloride 344458-15-7 10mM (in 1mL DMSO)
PJ34 hydrochloride (CAS 344458-15-7) is a small molecular inhibitor targeting poly(ADP-ribose) polymerase (PARP) an enzyme critical for DNA repair and cellular proliferation In vitro assays demonstrate dose-dependent inhibition of purified PARP activity with an EC50 of approximately 20 nM Unlike other inhibitors such as 3-aminobenzamide (3-AB) PJ34 lacks antioxidant properties and exhibits significantly higher inhibitory potency against PARP Experimental studies have shown PJ34 protects against peroxynitrite-induced cell necrosis (EC50 20 nM) and dose-dependently suppresses proliferation in HepG2 liver cancer cell lines enhancing chemotherapeutic efficacy and conferring neuroprotection in various disease models
Medchemexpress LLC C24:1 Dihydro 1-deoxyceramide (m18:0/24:1) | 1246298-60-1 | 99.0% | 634.11 | 1 MG
C24:1 Dihydro 1-deoxyceramide (m18:0/24:1) is a lipid molecule composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under conditions of obesity and type 2 diabetes (T2D). It cannot be further metabolized to more complex sphingolipid and is toxic when it accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro. This product is for research use only.
- Composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone.
- Accumulates under conditions of obesity and type 2 diabetes (T2D).
- Cannot be metabolized to more complex sphingolipids and is toxic upon accumulation.
- Increases in differentiated adipocytes in vitro.
- For research use only.
TARGETMOL CHEMICALS INC SEP-363856 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique non-D2/5-HT2A mechanism of action exerts its antipsychotic-like effects has the potential to treatment of schizophrenia. purity: 99%
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-1,2,3-triazole | ChemScene | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 25g | 632276599
4-Bromo-2-methyl-2H-1,2,3-triazole | ChemScene | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 95.000 | Cn1ncc(Br)n1 | 25g | 632276599