Oxazinanes
Cayman Chemical Fingolimod hydrochloride
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
TARGETMOL CHEMICALS INC GIVINOSTAT HYDROCHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor. purity: 98%
TARGETMOL CHEMICALS INC RIMONABANT HYDROCHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist binding selectively to central cannabinoid receptors (CB1) with high affinity. purity: 99%
TARGETMOL CHEMICALS INC PCLX-001 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT) specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM respectively. This compound demonstrates anti-tumor effects and effectively inhibits the early signaling of B-cell receptor (BCR). Consequently PCLX-001 is a valuable tool for researching B-cell malignancies [1] [2]. purity: 98%
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES TRIPROLIDINE HYDROCHLORIDE 1G
NC3373054 TRIPROLIDINE HYDROCHLORIDE 1G
Matrix Scientific 3,4-DIHYDRO-2H-1,4-BENZOXAZ-1G
3,4-Dihydro-2H-1,4-benzoxazine, 1g,C8H9NO, MFCD02181098, mw 135.17, [5735-53-5]
AdipoGen 5-DTAF hydrochloride
Chemical. CAS 21811-74-5. Formula C23H12Cl2N4O5 . HCl. MW 495.3 . 36.5. Synthetic. 5-DTAF is highly reactive with proteins. Unlike other reactive fluoresceins, 5-DTAF not only reacts with amino groups, but also reacts with thiol groups and even directly reacts with hydroxy groups such as polysaccharides and other alcohols in aqueous solution at pH above 9. Due to its high reactivity, 5-DTAF is also used to label carbohydrates. Spectral properties Abs/Em = 492/517 nm
AdipoGen N-2-Aminoethylbiotinamid HCl
Chemical. CAS 111822-45-8. Formula C12H23ClN4O2S. MW 322.85. Synthetic. Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
Sigma Aldrich Fine Chemicals Biosciences 4-(4-Bromophenyl)morpholine 97% | 30483-75-1 | MFCD04112483 | 25G
4-(4-Bromophenyl)morpholine 97% | Purity: 97% | Mol Wt: 242.11 | 30483-75-1 | MFCD04112483 | 25G
Sigma Aldrich Fine Chemicals Biosciences Aprepitant >=98% (HPLC) | 170729-80-3 | MFCD12912491 | 5MG
Aprepitant >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 534.43 | 170729-80-3 | MFCD12912491 | 5MG
AdipoGen Verapamil hydrochloride
Chemical. CAS 152-11-4. Formula C27H38N2O4 . HCl. MW 491.06. Synthetic Verapamil hydrochloride is an alpha-adrenergic receptor alpha-AR antagonist and calcium channel protein inhibitor that blocks the L-type Ca2 channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr P-glycoprotein. Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models.
AdipoGen Verapamil hydrochloride
Chemical. CAS 152-11-4. Formula C27H38N2O4 . HCl. MW 491.06. Synthetic Verapamil hydrochloride is an alpha-adrenergic receptor alpha-AR antagonist and calcium channel protein inhibitor that blocks the L-type Ca2 channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr P-glycoprotein. Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models.
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
A series of Pre-mixed SOLUTIONons of TRIZMA Base and TRIZMA HCl to provide commonly used pH values for Tris buffers. No mixing or pH adjustment necessary. Guaranteed accuracy /- 0.1 pH units.