Oxazinanes
Medchemexpress LLC PI-103 hydrochloride | 371935-79-4 | MFCD10687102 | ≥98.0% | 384.82 g/mol | C19H17ClN4O3 | 1 ML
PI-103 hydrochloride is a small-molecule research reagent that functions as a dual inhibitor of PI3K and mTOR. Supplied as a hydrochloride salt, it is used in cellular and biochemical studies to probe PI3K/mTOR signaling pathways and can be purchased as a solid or as a pre-made 10 mM solution in DMSO for immediate use.
- Dual PI3K and mTOR inhibition for pathway studies.
- Available as a 10 mM solution in DMSO for convenient use.
- Also available as a solid for custom formulation.
- High purity suitable for research (≥98%).
- Applicable to cellular and biochemical assay workflows.
eMolecules 1-(6-Aminonaphthalen-2-yl)ethanone | 7470-88-4 | MFCD20693622 | 250mg
Ambeed | 1-(6-Aminonaphthalen-2-yl)ethanone | 250mg | 600831588 | A158501 | | 7470-88-4 | MFCD20693622 | 185.226 | C12H11NO
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Apexbio Technology LLC Xamoterol hemifumarate 73210-73-8 25mg
Xamoterol hemifumarate (CAS 73210-73-8) is a selective 1-adrenergic receptor agonist targeting cardiac 1 receptors It is designed to activate 1-adrenergic signaling pathways thereby modulating myocardial function and cardiac electrophysiological processes Xamoterol hemifumarate exerts its biological activity primarily through 1-adrenergic receptor stimulation influencing downstream intracellular signaling cascades related to cardiac rhythm regulation In experimental settings it is utilized in vitro with cellular cardiac models and in vivo with animal models to assess 1-adrenergic receptor-mediated effects particularly in the interaction with cardiac ion channels such as the rapid delayed rectifier potassium current (IKr) Based on these pharmacological properties Xamoterol hemifumarate holds research potential in the study of arrhythmogenesis mechanisms and cardiac electrophysiology
Medchemexpress LLC p-SCN-Bn-DOTA 50mg | 127985-74-4 | 50 MG
p-SCN-Bn-DOTA is a bifunctional chelating reagent that couples a para-isothiocyanatobenzyl reactive group to a DOTA macrocycle, enabling covalent conjugation to biomolecules and stable chelation of radiometals for radioimmunoconjugation and radiopharmaceutical research.
- Enables covalent attachment to proteins and antibodies via an isothiocyanate group.
- Provides stable complexation of radiometals through the DOTA chelator.
- High purity suitable for research-grade radioconjugation.
- Solid, easy-to-weigh form for small-scale conjugation workflows.
- Manufacturer provides SDS and datasheet for safe handling and use.
Apexbio Technology LLC Rilmenidine (hemifumarate) 207572-68-7 10mg
Rilmenidine (hemifumarate CAS 207572-68-7) is an antihypertensive small molecule that primarily acts as an agonist at imidazoline I1 receptors within the rostral ventrolateral medulla thereby inhibiting the tonic activity of sympathoexcitatory neurons and reducing arterial pressure In vitro assays show that rilmenidine displays approximately 30-fold selectivity for imidazoline versus 2-adrenergic binding sites and a Ki of 7 1 nM for I1 receptors with significantly lower affinity for I2 sites (Ki 5 2 M) In vivo studies indicate efficacy in lowering blood pressure and ameliorating features of metabolic syndrome in rodent models as well as inducing autophagy and attenuating neurodegenerative pathology in a mouse model of Huntington s disease supporting its utility in cardiovascular and neurodegenerative research
Medchemexpress LLC 5-Bromopentanoyl chloride | 4509-90-4 | 98.63% | 199.47 | 10 G
5-Bromopentanoyl chloride is a PROTAC linker used in PROTAC ATR degrader-2 and for the synthesis of PROTACs. It is intended for research use only.
- PROTAC linker
- Suitable for synthesis of PROTACs
- For research use only
Apexbio Technology LLC Rilmenidine (hemifumarate) 207572-68-7 50mg
Rilmenidine (hemifumarate CAS 207572-68-7) is an antihypertensive small molecule that primarily acts as an agonist at imidazoline I1 receptors within the rostral ventrolateral medulla thereby inhibiting the tonic activity of sympathoexcitatory neurons and reducing arterial pressure In vitro assays show that rilmenidine displays approximately 30-fold selectivity for imidazoline versus 2-adrenergic binding sites and a Ki of 7 1 nM for I1 receptors with significantly lower affinity for I2 sites (Ki 5 2 M) In vivo studies indicate efficacy in lowering blood pressure and ameliorating features of metabolic syndrome in rodent models as well as inducing autophagy and attenuating neurodegenerative pathology in a mouse model of Huntington s disease supporting its utility in cardiovascular and neurodegenerative research
Selleck Chemical LLC Formoterol Hemifumarate S2020-50mg
Formoterol Hemifumarate (Eformoterol CGP 25827A NSC 299587 YM 08316 Formoterol fumarate) is a potent selective and long-acting 2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD)
eMolecules (R)-(+)-1-Phenylbutan-1-ol | 22144-60-1 | MFCD00004575 | 250mg
Oakwood Chemical | (R)-(+)-1-Phenylbutan-1-ol | 250mg | 537721599 | 355875 | | 22144-60-1 | MFCD00004575 | 150.221 | C10H14O
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Medchemexpress LLC PI-103 hydrochloride | 371935-79-4 | MFCD10687102 | 98.6% | 384.82 g/mol | C19H17ClN4O3 · HCl | 50 MG
PI-103 hydrochloride is a research-grade small molecule inhibitor of phosphatidylinositol 3-kinase (PI3K) and mechanistic target of rapamycin (mTOR). It is used in biochemical and cellular studies to probe PI3K/mTOR signaling and DNA-PK activity, and is supplied as a hydrochloride salt for consistent handling in laboratory assays.
- Dual PI3K and mTOR inhibitor useful for pathway interrogation.
- Potent biochemical activity with low-nanomolar IC50s against key kinases.
- Also inhibits DNA-PK, supporting DNA damage response studies.
- High purity suitable for research applications.
- Available in multiple sizes for screening or scale-up experiments.
eMolecules 6-Ethylpyrimidin-4(3H)-one | 124703-78-2 | MFCD05864423 | 250mg
Ambeed | 6-Ethylpyrimidin-4(3H)-one | 250mg | 525056886 | A145950 | | 124703-78-2 | MFCD05864423 | 124.143 | C6H8N2O
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Apexbio Technology LLC Xamoterol hemifumarate 73210-73-8 5mg
Xamoterol hemifumarate (CAS 73210-73-8) is a selective 1-adrenergic receptor agonist targeting cardiac 1 receptors It is designed to activate 1-adrenergic signaling pathways thereby modulating myocardial function and cardiac electrophysiological processes Xamoterol hemifumarate exerts its biological activity primarily through 1-adrenergic receptor stimulation influencing downstream intracellular signaling cascades related to cardiac rhythm regulation In experimental settings it is utilized in vitro with cellular cardiac models and in vivo with animal models to assess 1-adrenergic receptor-mediated effects particularly in the interaction with cardiac ion channels such as the rapid delayed rectifier potassium current (IKr) Based on these pharmacological properties Xamoterol hemifumarate holds research potential in the study of arrhythmogenesis mechanisms and cardiac electrophysiology