Oxazinanes
TARGETMOL CHEMICALS INC LEUKADHERIN-1 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen Decreasing leukocyte motility and transendothelial migration; reduces inflammation. purity: 98%
Medchemexpress LLC Flunarizine dihydrochloride | 30484-77-6 | 99.9% | 1 G
Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker and a D2 dopamine receptor antagonist. It exhibits anticonvulsive, antimigraine, and peripheral vasodilator effects.
- Potent dual Na+/Ca2+ channel (T-type) blocker
- D2 dopamine receptor antagonist
- Exhibits anticonvulsive activity
- Exhibits antimigraine activity
- Exhibits peripheral vasodilator effects
Apexbio Technology LLC TRIMETAZIDINE-HYDROCHLORIDE
Trimetazidine (hydrochloride) (CAS No 13171-25-0) is a pharmacological agent primarily studied in the cardiovascular research field Originating from anti-ischemic drug development it functions by optimizing cellular metabolism under hypoxic conditions predominantly through the inhibition of long-chain 3-ketoacyl-CoA thiolase in the cardiac mitochondrial beta-oxidation pathway This action shifts fatty acid oxidation to glucose oxidation enhancing myocardial glucose consumption and efficiency during ischemic episodes Common in vitro activity occurs in the nanomolar to low micromolar range Trimetazidine is frequently used in various experimental applications including cell models like cardiomyocytes animal studies investigating myocardial protection and drug screening for cardiovascular therapies Experimental concentrations typically depend on the specific research design enabling a tailored approach to exploring its cardioprotective effects in different contexts
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
Tris hydrochloride is used to prepare buffer mainly at a physiological range of 7.3 to 7.5. This buffer is well-suited with biological fluids. It is used in laboratories as primary pH standard in clinical laboratories.
Sigma Aldrich Fine Chemicals Biosciences TrizmaR hydrochloride solu
A series of Pre-mixed SOLUTIONons of TRIZMA Base and TRIZMA HCl to provide commonly used pH values for Tris buffers. No mixing or pH adjustment necessary. Guaranteed accuracy /- 0.1 pH units.
Cayman Chemical Nefazodone (hydrochloride), Purity: ≥98%, CAS: 82752-99-6, 250 mg
A serotonin, norepinephrine, and dopamine reuptake inhibitor (Kis = 137, 570, 2,380 nM, respectively); an antagonist of 5-HT2A, 5-HT1A, and histamine H1 receptors, as well as α1- and α2-ARs (Kis = 7.1, 52, 30, 5.5, and 84 nM, respectively); reduces immobility time in the tail suspension test in gerbils at 100 mg/kg; toxic to isolated human hepatocytes in a cultured sandwich hepatocyte preparation at 30 µM
Cayman Chemical Fingolimod (hydrochloride), Purity: ≥98%, CAS: 162359-56-0, 50 mg
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Cayman Chemical Fingolimod (hydrochloride), Purity: ≥98%, CAS: 162359-56-0, 250 mg
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Cayman Chemical SB-242084 (hydrochloride), Purity: ≥98%, CAS: 1049747-87-6, 10 mg
An antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors; brain penetrant with significant anxiolytic activity; used extensively in animal research
Cayman Chemical Fingolimod (hydrochloride), Purity: ≥98%, CAS: 162359-56-0, 100 mg
An immune modulator and a prodrug form of FTY720 phosphate; decreases the number of circulating lymphocytes in mice at 1 mg/kg; increases skin allograft survival in rats from 0.3-3 mg/kg; prevents disease development in a rat model of EAE; inhibits S1P lyase from 0.3-30 µM
Aobchem 1-Methyl-2-(4-nitrophenoxy)benzene | 97% | CAS 2444-29-3 | C13H11NO3 | 5g
1-Methyl-2-(4-nitrophenoxy)benzene | 97% | CAS 2444-29-3 | C13H11NO3 | 5g
![Aobchem 6-Bromospiro[2H-1 5-benzodioxepin-3(4H) 1 -cyclopropane] | ≥97% | CAS 1334499-94-3 | C11H11BrO2 | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5001085238.png-250.jpg)
Aobchem 6-Bromospiro[2H-1 5-benzodioxepin-3(4H) 1 -cyclopropane] | ≥97% | CAS 1334499-94-3 | C11H11BrO2 | 250mg
6-Bromospiro[2H-1 5-benzodioxepin-3(4H) 1 -cyclopropane] | ≥97% | CAS 1334499-94-3 | C11H11BrO2 | 250mg